| SATURDAY |
| 1:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair Robert Campbell (University of Utah) |
| 3:45 pm - 4:30 pm | Keynote Lecture |
| Discussion Leaders: Andy Weyrich (University of Utah) and Paul Hess (University of Pennsylvania)
|
| 3:45 pm - 4:15 pm | Lawrence Brass (University of Pennsylvania)
"Re-thinking the platelet response to injury"
|
| 4:15 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session I (Presenters with last name A-H) |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Hemostasis and Thrombosis I |
| Discussion Leaders: Susan Smyth (University of Kentucky) and Amal Arachiche (Case Western Reserve University) |
| 7:30 pm - 7:45 pm | Fatemeh Moheimani (RMIT University)
"Novel Molecular Association and Signaling Cross-Talk of ADP Purinergic Receptor, P2Y12 with Tetraspanin Superfamily Member, CD151 in Human and Mouse Platelets"
|
| 7:45 pm - 7:55 pm | Discussion |
| 7:55 pm - 8:10 pm | Angela Aggrey (University of Rochester)
"Platelet-Mediated Acute Phase Response and Subsequent Complement Activation is Protective Early in Experimental Cerebral Malaria"
|
| 8:10 pm - 8:20 pm | Discussion |
| 8:20 pm - 8:35 pm | Spencer Sullivan (Children's Hospital of Philadelphia)
"Correction of Glanzmann Thrombasthenia using Patient-Derived Induced Pluripotent Stem Cells"
|
| 8:35 pm - 8:45 pm | Discussion |
| 8:45 pm - 9:00 pm | Adam Corken (University of Arkansas for Medical Sciences)
"Platelet Glycoprotein Ib-IX in Thrombosis and Inflammation"
|
| 9:00 pm - 9:10 pm | Discussion |
| 9:10 pm - 9:25 pm | Brian Branchford (University of Colorado)
"Novel Gas6/TAM Signaling Pathway Inhibitors Decrease Platelet Activation and Thrombosis" |
| 9:25 pm - 9:30 pm | Discussion |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Hemostasis and Thrombosis II |
| Discussion Leaders: James Morrissey (University of Illinois) and Kristine Alexander (Oregon Health and Science University)
|
| 9:00 am - 9:15 am | Michelle Homsher (Children's Hospital of Philadelphia)
"Constrained Binding and Conformational Dynamics Dictate the Recognition and Cleavage of Prothrombin by Prothrombinase"
|
| 9:15 am - 9:25 am | Discussion |
| 9:25 am - 9:40 am | Thomas Colace (University of Pennsylvania)
"Thrombus Growth and Embolism on Tissue Factor-Bearing Collagen Surfaces Under Flow: Role of Thrombin With and Without Fibrin"
|
| 9:40 am - 9:50 am | Discussion |
| 9:50 am - 10:05 am | Narjes Tavoosi (University of Illinois)
"Human Factor VIIa and Activated Protein C are Phosphatidic Acid-Binding Proteins" |
| 10:05 am - 10:15 am | Discussion |
| 10:15 am - 10:30 am | Paul Kim (Thrombosis and Atherosclerosis Research Institute and McMaster University)
"Kringle Domains of Plasmin are Essential for Efficient Degradation of Fibrin but not Fibrinogen"
|
| 10:30 am - 10:40 am | Discussion |
| 10:40 am - 10:55 am | Audrey Cleuren (University of Michigan)
"Early Death of Factor V Leiden Hemizygous Mice: a Fatal Absence of Wild Type FV Anticoagulant Function" |
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session II (presenters with last names K-Z) |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Hemostasis and Thrombosis III |
| Discussion Leaders: Jorge Di Paola (University of Colorado - Denver) and Rami Khoriaty (University of Michigan)
|
| 1:30 pm - 1:45 pm | Maria Aleman (University of North Carolina at Chapel Hill)
"Fibrin(ogen)-Leukocyte Integrin AlphaMbeta2 Interactions Orchestrate Venous Thrombus Formation and Resolution"
|
| 1:45 pm - 1:50 pm | Discussion |
| 1:50 pm - 2:05 pm | Eimear Gleeson (Trinity College Dublin)
"Activated Factor X is a Novel Regulator of Toll-like Receptor Proinflammatory Signaling on Monocytes and Macrophages"
|
| 2:05 pm - 2:10 pm | Discussion |
| 2:10 pm - 2:25 pm | Gilbert Schaeffer (University of Iowa)
"Formation of Dense VWF 'nets' from Cultured HUVECs in a Parallel Plate Flow Chamber - a Possible Pathophysiological Link to TTP?"
|
| 2:25 pm - 2:30 pm | Discussion |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
| 3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |
