| SATURDAY |
| 1:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Chair Angela Aggrey (Johns Hopkins University) and Introduction to GRS |
| 3:45 pm - 4:30 pm | Keynote Session |
| Discussion Leaders: Jorge DiPaola (University of Colorado) and Thomas Colace (University of Pennsylvania) |
| 3:45 pm - 4:15 pm | Jane Freedman (University of Massachusetts)
"Developing a Vibrant Research Career in Hemostasis and Thrombosis Research"
|
| 4:15 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session I (Presenters with last name A-J) |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Hemostasis and Thrombosis |
| Discussion Leaders: Paula Tracy (University of Vermont) and Bethany Walton (University of North Carolina) |
| 7:30 pm - 7:45 pm | Yacine Boulaftali (University of North Carolina)
"The Calcium-Binding Protein S100A1 Negatively Regulates Collagen-Dependent Platelet Activation and Thrombosis in Mice"
|
| 7:45 pm - 7:55 pm | Discussion |
| 7:55 pm - 8:10 pm | Laura Haynes (University of Vermont)
"Platelet-Derived Microparticles Attenuate Their Procoagulant Nature via
the Prothrombinase Complex and the Function of Activated Protein C"
|
| 8:10 pm - 8:20 pm | Discussion |
| 8:20 pm - 8:35 pm | Richard Li (University of Pennsylvania)
"Recapitulation of Trauma Coagulopathy in a Whole Blood Microfluidic Flow Assay"
|
| 8:35 pm - 8:45 pm | Discussion |
| 8:45 pm - 9:00 pm | Timothy Sendall (University of Cambridge, UK)
"Modeling the Intrinsic Tenase Complex from the Homologous Structure of Pseutarin c."
|
| 9:00 pm - 9:10 pm | Discussion |
| 9:10 pm - 9:25 pm | Nikolett Wohner (INSERM, France)
"Shear Stress-Independent Binding of von Willebrand Factor Mutants to LRP1
May Explain Their Increased Clearance Rate"
|
| 9:25 pm - 9:30 pm | Discussion |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 10:00 am | Inflammation, Immunity and Signaling |
| Discussion Leaders: Craig Morrell (University of Rochester) and Renata Grozovsky (Brigham & Women's) |
| 9:00 am - 9:15 am | Caterina Casari (University of North Carolina)
"Von Willebrand Disease Type 2B: A Platelet Point of View"
|
| 9:15 am - 9:25 am | Discussion |
| 9:25 am - 9:40 am | Yuhang Zhou (Thomas Jefferson University)
"miR-148a and miR-25 Target TULA-2 and Regulate Human Platelet FcgRIIA Signaling"
|
| 9:40 am - 9:50 am | Discussion |
| 9:50 am - 10:00 am | Coffee Break |
| 10:00 am - 11:00 am | Professional Development Session |
| Hard Times for These Times: How to Plan for a Career in Science |
| Featuring a panel of postdoctoral trainees, early investigators & established principal investigators |
| 11:00 am - 12:30 pm | Poster Session II (Presenters with last name K-Z) |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Inflammation, Immunity and Signaling (continued) |
| Discussion Leaders: Alisa Wolberg (University of North Carolina) and Leila Noetzli (University of Colorado) |
| 1:30 pm - 1:45 pm | Monica Arman (University of Birmingham, UK)
"Platelet Activation by Gram-Positive Bacteria: Key Roles for Immune Receptor Fc Gamma RIIA, Integrin Alpha IIb Beta 3, and Chemokine Platelet Factor 4"
|
| 1:45 pm - 1:50 pm | Discussion |
| 1:50 pm - 2:05 pm | Rachit Badolia (Temple University)
"PAK and Akt Interactions Regulate PAR-Mediated Akt Translocation to Membrane in Platelets: A Novel PIP3- Independent Mechanism"
|
| 2:05 pm - 2:10 pm | Discussion |
| 2:10 pm - 2:25 pm | Rebecca Markovitz (Emory University)
"B-Bomb: Eradicating the Humoral Immune Response to FVIII by Antigen Specific Deletion of Naïve and Memory B Cells"
|
| 2:25 pm - 2:30 pm | Discussion |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
| 3:00 pm | Seminar Concludes |
