Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Initiating a Career in Blood Research
Discussion Leader: Gow Arepally (Duke University School of Medicine, United States)
3:45 pm - 4:15 pm
Marvin Nieman (Case Western Reserve University, United States)
"Initiating a Career in Blood Research"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Building on the Basics: New Discoveries in Thrombosis and Hemostasis
Discussion Leaders: Traci Mondoro (NHLBI/NIH, United States) and Daniëlle Coenen (University of Kentucky, United States, United States)
7:30 pm - 7:45 pm
Irina Portier (University of Utah, United States)
"The mTOR Pathway in Platelets Contributes to the Pathophysiology of Experimental Cerebral Malaria"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:10 pm
Dre'Von Dobson (University of North Carolina at Chapel Hill, United States)
"Functional Characterization of Loci Associated with Circulating Fibrinogen Levels"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
Siobhan Branfield (Oakland University, United States)
"Deciphering the TLT-1 Fibrinogen Ligand Interaction"
8:35 pm - 8:40 pm
Discussion
8:40 pm - 9:00 pm
Vladimir Kolyadko (The Children's Hospital of Philadelphia, United States)
"Allosteric Regulation of Coagulation Factor IXa Revealed by X-Ray Crystallography"
9:00 pm - 9:05 pm
Discussion
9:05 pm - 9:25 pm
Helen Fogarty (Royal College of Surgeons in Ireland, Ireland)
"Blood Transfusion Maintains Endothelial Cell Quiescence - Implications in Stroke Prevention in Paediatric Sickle Cell Anaemia"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Platelets and Other Cells in Coagulation
Discussion Leaders: Sidney Whiteheart (University of Kentucky, United States) and Ratnashree Biswas (Versiti Blood Research Institute, United States)
9:00 am - 9:15 am
Frederik Denorme (University of Utah, United States)
"Procoagulant Platelet – Neutrophil Interactions Exacerbate Ischemic Stroke"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Sarah Beck (University of Würzburg, Germany)
"Spatio-Temporal Control of Fibrin Formation by Platelet Glycoprotein V"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Gagan Flora (University of Iowa, United States)
"The Role of Pyruvate Dehydrogenase Kinases in Regulating Platelet Function and Thrombosis"
9:55 am - 10:00 am
Discussion
10:00 am - 11:00 am
Panel Discussion
Pathways to Success: Navigating a Career in Science
Traci Mondoro (NHLBI/NIH, United States)
Joshua Muia (Oklahoma State University Center for Health Sciences, United States)
Emily Waters (Novo Nordisk Inc, United States)
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Crosstalk with Coagulation
Discussion Leaders: Marvin Nieman (Case Western Reserve University, United States) and Maria Barrachina (Harvard Medical School, Boston Children's Hospital, United States)
1:30 pm - 1:45 pm
Claudius Witzler (University Medical Center of the Johannes Gutenberg University Mainz, Germany)
"Regulation of Metabolic Inflammation by Coagulation Signaling"
1:45 pm - 1:50 pm
Discussion
1:50 pm - 2:05 pm
Chi Peng (University of Kentucky, United States)
"Characterization of Platelets from A Newly Developed Obese Mouse Model: MS-NASH"
2:05 pm - 2:10 pm
Discussion
2:10 pm - 2:25 pm
Aisling Rehill (Royal College of Surgeons in Ireland (RCSI), Ireland)
"Metabolic Reprogramming is Essential for Myeloid Cell Hypercoagulability"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes
