Sunday, June 28
Discussion Leader: Joe Konopelski, UC - Santa Cruz
- William Roush (University of Michigan) - Problems in Glycoside Chemistry: Progress Towards the Synthesis of Aureolic Acid Antitumor Antibiotics
- Vincent Rocco (Eli Lilly) Palladium-Mediated Cross Coupling Reactions in Heterocyclic Construction
Monday, June 29
Discussion Leader: Lou Jungheim, Eli Lilly
- Peter Jacobi (Dartmouth University) - Synthesis and Study of Biologically Important Tetrapyrroles
- John Macor (Bristol Myers-Squibb) - A Tale of Two Receptors: Synthesis of Agonists for the Serotonergic and Cholinergic Families of Receptors
- Edward Taylor (Princeton University) Multiple Inhibition of Folate-Dependent Enzymes--Discovery of an Exceptionally Promising Antitumor Agent
Discussion Leader: James Audia, Eli Lilly
- Duane Burnett (Schering-Plough) - Design and Synthesis of Biochemical Tools for the Investigation of the Mechanism of Action of the ß-Lactam Cholesterol Absorption Inhibitor, Sch 58235
- Joachim Schantl, University of Innsbruck - Azomethine Imines in Four- and Five-Membered Rings: Stable Cyclic Valence Isomers of an alpha-(Phenyldiazenyl)ketocarbene
- Steven Burke (University of Wisconsin-Madison) - Conformational Engineering and Convergent Functionality: Applications to Synthetic Ionophores and Ion Channel Templates
Tuesday, June 30
Discussion Leader: Karen Romines, Pharmacia & Upjohn
- Shuji Kanemasa (Kyushu University) - Interaction of 1,3-Dipoles with a Lewis Acid - The Case of Diazo Compounds
- Ronald Ratcliffe (Merck) - Synthesis of a New Series of Carbapenem Antibiotics Active Against MRSA
- Jacquelyn Gervay (University of Arizona) - Synthesis and Structural Studies of Novel Carbohydrate-Based Heterocycles
Discussion Leader: Paul GFeldman, Glaxo-Wellcome
- Joel Hawkins (Pfizer) - New Asymmetric Aldol and Ortho Boration Chemistry for a Drug Candidate
- Stephen Bergmeier (Ohio State University) - Intramolecular Cyclization Reactions of Aziridine Allysilanes
- Michael Martinelli (Eli Lilly) - Synthetic Studies on the Anti-Tumor Agent Cryptophycin 52 (LY355703)
Wednesday, July 1
Discussion Leader: Joachim Schantl, University of Innsbruck
- Michelle Weidner-Wells (R. W. Johnson Pharmaceutical Research Institute) - An Unexpected Reversal of Regioselectivity in the Dipolar Cycloaddition Reactions of Nitrile Oxides with Tertiary Cinnamides and Crotonamides
- David Van Vranken (University of California-Irvine) - Protein Aging: Clues for Organic Synthesis
- Robert Batey (University of Toronto) - New Synthetic Approaches toward Pyrrolidine and Indolizidine Synthesis
- Marco Ciufolini (Université Claude Bernard, Lyon) - Synthetic Studies on Heterocyclic Natural Products
Discussion Leader: Kenneth Doxsee, University of Oregon
- George Sheppard (Abbott) - Synthetic Approaches to a Novel Series of MMP Inhibitors
- Partha Ray (University of Memphis) - Synthesis and Antitumor Properties of Pyrimidoazepine-Based Tetrahydrofolic Acid Derivatives
- Philip Kocienski (University of Glasgow) - Synthesis of the Marine Antitumour Agents of the Pederin-Mycalamide Class
Thursday, July 2
Discussion Leader: Susan Tamura, Corvas
- Russell Dushin (Wyeth-Ayerst) - A New Route to Enaminone Intermediates
- Eric Edstrom (University of Montana) - Chemistry of Indole-3-triflates
- Harry Finch (Glaxo-Wellcome) - A Natural Product Lead Into Strained [5,5]Bicyclic-trans-Lactones and -Lactams: Total Synthesis and Potential Applications
Discussion Leader: Dennis Hlasta, R.W. Johnson PRI
- James Cook (University of Wisconsin-Milwaukee) - Enantiospecific Synthesis of Sarpajine and Ajmaline Alkaloids via the Asymmetric Pictet-Spengler Reaction
- Joe Konopelski - Vice Chair's Remarks
|