Sunday, June 27

Evening Session (Paul Feldman, Glaxo Wellcome, Discussion Leader)

7:20-7:30 P.M. Greeting by Gordon Conference Chair & Staff

7:30-8:15 Edward Grabowski, Merck Research Laboratories
Recent Studies in the Design and Development of Practical Syntheses

8:15-8:30 Discussion

8:30-9:25 Scott E. Denmark, University of Illinois
Enantioselective Total Synthesis of Alkaloids by the Tandem [4+2]/[3+2] Cycloaddition of Nitroalkenes

9:25-9:40 Discussion

Monday, June 28

Morning Session (Rob Hoffman, New Mexico State University, Discussion Leader)

8:30-9:00 A.M. Photograph

9:00-9:50 Andrew C. Hamilton, Yale University
Protein Surface Recognition by Synthetic Receptors: An Approach to Artificial Antibodies

9:50-10:05 Discussion

10:05-10:50 Robert W. Armstrong, AMGEN Corporation
Synthesis of Natural Product Inhibitors of Phosphatases - Understanding Large-Large Interactions

10:50-11:05 Discussion

11:05-11:20 Break

11:20-12:10 Alois Fürstner, Max-Plank-Institut Für Kohlenforschung
Catalytic Heterocycle Syntheses: New Methods and Applications

12:10-12:25 Discussion

4:00-6:00 P.M. Poster Session #1

Evening Session (Toni Cancellor, Pharm-Eco Laboratories, Discussion Leader)

7:30-8:00 P.M. Gee-Hong Kuo, The R.W. Johnson Pharmaceutical Research Institute
Synthesis and Structure-Activity Relationships of Phenylpiperazine Derivatives. A New Series of Potent and Selective Alpha 1a-Adrenergic Receptor Antagonists

8:00-8:10 Discussion

8:10-8:30 Scott J. Miller, Boston College
Discovery of Minimal Peptides for Asymmetric Catalysis and Synthesis

8:30-8:40 Discussion

8:40-9:40 Dale L. Boger, The Scripps Research Institute
Total Synthesis and Biological Properties of Complex Heterocyclic Natural Products

9:40 Discussion

Tuesday, June 29

Morning Session (Tim Gallagher, University of Bristol, Discussion Leader)

8:30-9:15 A.M. Craig J. Forsyth, University of Minnesota
Synthesis of Complex Heterocyclic Marine Natural Products

9:15-9:25 Discussion

9:25-9:55 Jeffrey A. Dodge, Lilly Research Labs
Asymmetric Synthesis of Imidazole-Derived Growth Hormone Secretagogues

9:55-10:05 Discussion

10:05-10:30 Break, Meeting of GRC Heterocycles Chairs - Past, Present, & Future

10:30-11:15 C. Oliver Kappe, Karl-Franzens-University Graz, Austria
Synthesis and Stereochemistry of Biofunctional Dihydropyrimidones

11:15-11:25 Discussion

11:25-12:15 Mukund P. Sibi, North Dakota State University
Enantioselective Conjugate Additions in Natural Product Synthesis

12:15-12:30 Discussion

Evening Session (Scott Miller, Boston College, Discussion Leader)

7:30-8:00 P.M. John M. Nuss, Chiron Corporation
New Methods for the Solid-Supported Synthesis of Biologically Active Heterocycles

8:00-8:10 Discussion

8:10-8:30 Nancy Totah, University of Iowa
Studies toward the synthesis of a Phomactin A Model

8:30-8:40 Discussion

8:40-9:40 David B. Collum, Cornell University
Structure-Reactivity Relationships in Lithium Dialkylamides: Lessons Learned from Solution Kinetics (With No Math!)

9:40 Discussion

Wednesday, June 30

Morning Session (Jeff Aube, University of Kansas, Discussion Leader)

8:30-9:15 A.M. Steve Angle, University of California, Riverside
Development and Application of New Methodology for the Synthesis of Heterocycles

9:15-9:25 Discussion

9:25-9:55 Stephen A. Godleski, Kodak Research Laboratories
Radical-Ion Chemistry in Photography

9:55-10:05 Discussion

10:05-10:30 Break, Nominations for 2001 Chair

10:30-11:15 Henk Hiemstra, University of Amsterdam New Developments in Heterocyclic Synthesis via Heteroatom-stabilized Carbocations

11:15-11:25 Discussion

11:25-12:15 Samuel H. Gellman, University of Wisconsin
Folding of Peptides and Peptide-like Molecules

12:15-12:30 Discussion

4:00-6:00 P.M. Poster Session #2

Evening Session (George Sheppard, Abbott Laboratories, Discussion Leader)

7:30-8:00 P.M. Steven W. Elmore, Abbott Laboratories
Design and Synthesis of Non-Steroidal, Selective Glucocorticoid Receptor Modulators

8:00-8:10 Discussion

8:10-8:30 Gregory R. Cook, North Dakota State University
Utility of the Palladium-Mediated Epimerization and Allylic Substitution of 5-Vinyl-1, 3-oxazolidine-2-ones and Oxazolines for Asymmetric Synthesis

8:30-8:40 Discussion

8:40-9:40 Cynthia J. Burrows, University of Utah
The One-Electron Chemistry of Guanine in DNA and RNA

9:40 Discussion

Thursday, July 1

Morning Session (Andras Kotschy, Eotvos Lorand University, Budapest, Discussion Leader)

9:00-9:45 A.M. Carolyn Bertozzi, University of California, Berkeley
New Directions in Glycoprotein Synthesis

9:45-9:55 Discussion

9:55-10:35 James C. Wisowaty, Glaxo Wellcome
Progress in the Development of an Ultra-Short-Acting Neuromuscular Blocking Agent

10:35-10:50 Discussion

10:50-11:10 Election of 1999 Chair

11:10-11:40 Break

11:40-12:25 Takayuki Shioiri, Nagoya City University
New Construction of Heterocycles Utilizing Silyl-Based Reagents

12:25-12:35 Discussion

4:00-6:00 P.M. Chairman’s Reception & Wine Tasting

6:15-7:15 Banquet

Evening Session (Tom Goodwin, Hendrix College, Discussion Leader)

7:30-8:30 P.M. Amos B. Smith III, University of Pennsylvania
Recent Advances in the Total Synthesis of Architecturally Complex Natural Products

8:30-8:45 Discussion

8:45-??? Paul Feldman: Vice Chairman’s Remarks

Friday, July 2