| Saturday |
| 2:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Keynote Session: The Future of Chemical Biology |
| Discussion Leader: Justin Rettenmaier (University of California, San Francisco, USA) |
| 3:45 pm - 4:25 pm | Jay Bradner (Harvard Medical School, USA)
"Chemical Biology in the Post-Genomic Era" |
| 4:25 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Advances in Synthetic Chemistry and Peptidomimetics |
| Discussion Leader: Zachary Hill (University of California, San Francisco, USA) |
| 7:30 pm - 7:50 pm | Vanessa Kung (University of Wisconsin - Madison, USA)
"Design and Characterization of Peptides that Adopt Amyloid-Like Folds in Aqueous Solution" |
| 7:50 pm - 7:55 pm | Discussion |
| 7:55 pm - 8:15 pm | Kimberly Geoghegan (ETH Zurich, Switzerland)
"Bespoke SnAP Reagents for the Synthesis of Spirocyclic and Bicyclic N-Heterocycles" |
| 8:15 pm - 8:20 pm | Discussion |
| 8:20 pm - 8:40 pm | Melanie Trobe (Graz University of Technology, Austria)
"A Modular Synthesis of Teraryl-Based Alpha-Helix Mimetics for Inhibition of Protein-Protein-Interactions" |
| 8:40 pm - 8:45 pm | Discussion |
| 8:45 pm - 9:05 pm | Andrew MacConnell (The Scripps Research Institute, USA)
"DNA-Encoded Solid Phase Synthesis: Encoding Language Design and Complex Oligomer Synthesis" |
| 9:05 pm - 9:10 pm | Discussion |
| 9:10 pm - 9:25 pm | Keith Bentley (Georgetown University, USA)
"Simultaneous Determination of the Enantiomeric Excess and Concentration of Chiral Compounds from a Crude Reaction Mixture with a Chiroptical Sensor" |
| 9:25 pm - 9:30 pm | Discussion |
| Sunday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Development of Chemical Tools to Interrogate Biology |
| Discussion Leader: Lindsay Repka (University of Illinois at Urbana-Champaign, USA) |
| 9:00 am - 9:20 am | Joshua Judkins (Pfizer Neuroscience, USA)
"Development and Application of a Chemical Probe for the N-Methyl-D-Aspartate Receptor" |
| 9:20 am - 9:25 am | Discussion |
| 9:25 am - 9:45 am | Cynthia Chio (University of California, Irvine, USA)
"Rational Design of Allosteric-Inhibition Sites in Classical Protein Tyrosine Phosphatases" |
| 9:45 am - 9:50 am | Discussion |
| 9:50 am - 10:10 am | Bryon Drown (University of Illinois at Urbana-Champaign, USA)
"Chemical Methods to Measure and Modulate ADP-Ribosylhydrolase Activities" |
| 10:10 am - 10:15 am | Discussion |
| 10:15 am - 10:35 am | JingXin Liang (California Institute of Technology, USA)
"Addressing Geographic Diversity in Malarial Biomarkers with Epitope-Catalyzed Screening" |
| 10:35 am - 10:40 am | Discussion |
| 10:40 am - 10:55 am | Monica Kasbekar (National Institutes of Health, USA)
"Discovery of a Selective Inhibitor of the Fumarase Enzyme of Mycobacterium tuberculosis" |
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Finding Vulnerabilities of Cancer and Malaria |
| Discussion Leader: Elizabeth Parkinson (University of Illinois at Urbana-Champaign, USA) |
| 1:30 pm - 1:50 pm | Sofia Santos (Massachusetts General Hospital, USA)
"Plasmodium tRNA Synthetases as Next Generation Druggable Dual-Stage Targets for Malaria Elimination" |
| 1:50 pm - 2:00 pm | Discussion |
| 2:00 pm - 2:20 pm | Landon Edgar (University of Toronto, Canada)
"Organotellurium Probes for Quantitative, Multiparameter Biology: A Study in Cellular Hypoxia" |
| 2:20 pm - 2:30 pm | Discussion |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
| 3:00 pm | Seminar Concludes |
