Saturday 
 
 
2:00 pm - 5:00 pm 
	
Arrival and Check-in
 
 
						 
						 
					
						
						
3:30 pm - 3:45 pm 
	
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
 
 
						 
						 
					
						
						
3:45 pm - 4:30 pm 
	
Keynote Session: Expanding the Druggable Proteome 
 
 
 
						 
						 
					
						
						
3:45 pm - 4:20 pm 
	
"Activity-Based Proteomics: Protein and Ligand Discovery on a Global Scale" 
 
 
 
						 
						 
					
						
						
4:20 pm - 4:30 pm 
	
Discussion
 
 
						 
						 
					
						
						
4:30 pm - 6:00 pm 
	
Poster Session 
 
 
						 
						 
					
						
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						 
						 
					
						
						
7:30 pm - 9:30 pm 
	
New Screening Technologies in Chemical Biology 
 
 
 
						 
						 
					
						
						
7:30 pm - 7:45 pm 
	
"Tailored Activity-Based Probes for Profiling Candidate Depalmitoylases" 
 
 
 
						 
						 
					
						
						
7:45 pm - 7:55 pm 
	
Discussion
 
 
						 
						 
					
						
						
7:55 pm - 8:10 pm 
	
"Ultra-Large Library Docking for Discovering New Chemotypes" 
 
 
 
						 
						 
					
						
						
8:10 pm - 8:20 pm 
	
Discussion
 
 
						 
						 
					
						
						
8:20 pm - 8:35 pm 
	
"Off-DNA Affinity Screening of DNA-Encoded Libraries" 
 
 
 
						 
						 
					
						
						
8:35 pm - 8:45 pm 
	
Discussion
 
 
						 
						 
					
						
						
8:45 pm - 9:00 pm 
	
"Using Thermal Proteome Profiling to Identify the Molecular Components of Calcium Signaling and Homeostasis in Apicomplexan Parasites" 
 
 
 
						 
						 
					
						
						
9:00 pm - 9:10 pm 
	
Discussion
 
 
						 
						 
					
						
						
9:10 pm - 9:30 pm 
	
General Discussion
 
 
						 
						 
					
						
						
	Sunday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						 
						 
					
						
						
9:00 am - 11:00 am 
	
Chemical Editing of Nucleic Acids and Proteins / Mentorship Component: Research in Academia, Industry and Government Agencies 
 
 
 
						 
						 
					
						
						
9:00 am - 9:15 am 
	
"N4-Acetylcytidine Alters Stability and Function of RNA" 
 
 
 
						 
						 
					
						
						
9:15 am - 9:20 am 
	
Discussion
 
 
						 
						 
					
						
						
9:20 am - 9:35 am 
	
"Small Molecule Stabilization of the GR 14-3-3 Protein-Protein Interaction (PPI)" 
 
 
 
						 
						 
					
						
						
9:35 am - 9:40 am 
	
Discussion
 
 
						 
						 
					
						
						
9:40 am - 9:55 am 
	
"A Chemical Probe to Monitor the Parkinsonism-Associated Protein DJ-1 in Live Cells" 
 
 
 
						 
						 
					
						
						
9:55 am - 10:00 am 
	
Discussion
 
 
						 
						 
					
						
						
10:00 am - 11:00 am 
	
Panel Discussion 
Research in Academia, Industry and Government Agencies 
 
 
 
						 
						 
					
						
						
11:00 am - 12:30 pm 
	
Poster Session 
Coffee will be served in the poster area from 11:00 am - 11:30 am 
 
 
						 
						 
					
						
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						 
						 
					
						
						
1:30 pm - 2:30 pm 
	
Advances in Synthetic Chemistry and Drug Development 
 
 
 
						 
						 
					
						
						
1:30 pm - 1:45 pm 
	
"An Alternative and Accurate Approach for Sub-Milligram Solid Dispensing for Practical High-Throughput Experimentation" 
 
 
 
						 
						 
					
						
						
1:45 pm - 1:50 pm 
	
Discussion
 
 
						 
						 
					
						
						
1:50 pm - 2:05 pm 
	
"Progress Towards the Autonomous Discovery of New p53/hMDM2 PPI Inhibitors" 
 
 
 
						 
						 
					
						
						
2:05 pm - 2:10 pm 
	
Discussion
 
 
						 
						 
					
						
						
2:10 pm - 2:25 pm 
	
"Asymmetric Reaction Screening with a Molecular Click Chemistry Sensor" 
 
 
 
						 
						 
					
						
						
2:25 pm - 2:30 pm 
	
Discussion
 
 
						 
						 
					
						
						
2:30 pm - 3:00 pm 
	
Evaluation Period 
Fill in GRS Evaluation Forms 
 
 
						 
						 
					
						
						
3:00 pm 
	
Seminar Concludes