This new Gordon Research Conference is a combination of the former Gordon Conferences on Hormone Action, Hormones and Development, and Hormonal Carcinogenesis which have been discontinued three years ago. The focus of this conference will be on the role of steroid hormones in development, oncogenesis, and cancer and the underlying molecular and cellular mechanisms. This Gordon Conference will bring together cutting-edge experts in these areas of research and young investigators to discuss mechanistic concepts broadly across phyla and their translation to basic problems in development and cancer. The highly multidisciplinary and "transformational" environment that will be created during this meeting in formal and informal contexts is intended to result in cross-fertilization and development of significant new ideas. The program will include state-of-the-art discussions of important areas such as hormone action during early and pubertal development, steroid hormone action in stem cells, non-steroid nuclear receptors and non-nuclear steroid hormone receptors, the role of stromal-epithelial interactions, signaling and receptor cross-talk, non-genomic and epigenetic actions of hormones, molecular basis of hormone-related cancer, environmental endocrine disrupting agents, circadian genes in development and cancer, hormonal agents in cancer prevention and therapy, and a wide range of model systems applicable to the study of hormone action in development, oncogenesis, and cancer.