SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | KEYNOTE LECTURES: NUCLEAR RECEPTORS IN DIFFERENTIATION AND CANCER |
| Discussion Leaders: Gail S. Prins (University of Illinois at Chicago) & Kevin White (University of Chicago) |
7:45 pm - 8:25 pm | M. Geoff Rosenfeld (University of California, San Diego)
"Life, Death, and Translocation: Epigenetic and Nuclear Architectural Regulatory Events in Hormone Action" |
8:25 pm - 8:35 pm | Discussion |
8:35 pm - 9:15 pm | Benita Katzenellenbogen (University of Illinois)
"Estrogens and Estrogen Receptor Signaling in Breast Cancer" |
9:15 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
8:45 am | Group Photo |
9:00 am - 12:30 pm | RECENT ADVANCES IN STEROID HORMONE ACTION |
| Discussion Leaders: Geoffrey Greene (University of Chicago) & Kenneth Korach (NIEHS) |
9:00 am - 9:05 am | Opening Remarks |
9:05 am - 9:30 am | Geoffrey Greene (University of Chicago)
"Molecular Mechanisms Of Agonistic And Antagonistic Actions Of SERMs With ERα And ERβ" |
9:30 am - 9:40 am | Discussion |
9:40 am - 10:05 am | Carol Lange (University of Minnesota)
"Progesterone Receptor Rapid Signaling" |
10:05 am - 10:15 am | Discussion |
10:15 am - 10:45 am | Coffee Break |
10:45 am - 11:10 am | Gordon Hager (National Cancer Institute)
"Interaction Of Nuclear Receptors With The Chromatin Landscape" |
11:10 am - 11:25 am | Discussion |
11:25 am - 11:50 am | Fraydoon Rastinejad (University of Virginia)
"Structural Organization of the Intact PPARƒ×-RXR Complex" |
11:50 am - 12:05 pm | Discussion |
12:05 pm - 12:20 pm | Young Investigator Short Talk: Ralf Kittler (University of Chicago)
"A Nuclear Receptor Cis-regulatory Map for Breast Cancer" |
12:20 pm - 12:25 pm | Discussion |
12:25 pm - 12:30 pm | Announcements regarding Business Meeting and Elections |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session I |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | HORMONAL REGULATION OF DEVELOPMENT |
| Discussion Leaders: Henry Krause (University of Toronto) & Jose Russo (Fox Chase Cancer Center) |
7:30 pm - 7:55 pm | Adam Antebi (Baylor College of Medicine)
"Nuclear Receptor Regulation of microRNAs in the C. elegans Heterochronic Circuit" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:30 pm | Wellington Cardoso (Boston University)
"Retinoic Acid Regulation Of Lung Development" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:05 pm | Liang Ma (Washington University)
"Molecular Mechanisms of Female Reproductive Tract Development by Estrogens" |
9:05 pm - 9:15 pm | Discussion |
9:15 pm - 9:25 pm | Young Investigator Short Talk: Anna Jang (Johns Hopkins University)
"Border Cell Migration requires Integration of Spatial and Temporal Signals by the BTB Protein Abrupt" |
9:25 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | STEROID ACTION IN BREAST AND PROSTATE CANCER |
| Discussion Leaders: Suzanne Fuqua (Baylor College of Medicine) & Maarten Bosland (University of Illinois at Chicago) |
9:00 am - 9:25 am | Karen Knudsen (Thomas Jefferson University)
"Androgen Receptor, The Cell Cycle And Prostate Cancer" |
9:25 am - 9:40 am | Discussion |
9:40 am - 10:05 am | Gerry Coetzee (University of Southern California)
"Androgen Receptor and Prostate Cancer Risk at 8q24" |
10:05 am - 10:15 am | Discussion |
10:15 am - 10:45 am | Coffee Break |
10:45 am - 11:10 am | Patricia Elizalde (Instituto de Biología y Medicina Experimental, Buenos Aires)
"Progesterone Receptor Action In Breast Cancer" |
11:10 am - 11:25 am | Discussion |
11:25 am - 11:50 am | Judy Bolton (University of Illinois at Chicago)
"Estrogen Quinones In Carcinogenesis" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:15 pm | New Investigator Short Talk: Laura Bohrer (University of Minnesota)
"Biphasic Regulation of histone methyltransferase EZH2 by androgens: Implications for novel mechanisms of prostate development and prostate cancer progression" |
12:15 pm - 12:20 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session I (continued) |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | HORMONAL CARCINOGENESIS: ALTERNATE PATHWAYS & SITES |
| Discussion Leaders: Cheryl Walker (University of Texas) & Shuian Chen (City of Hope) |
7:30 pm - 7:35 pm | Opening Remarks |
7:35 pm - 8:00 pm | Lois Mulligan (Queens University, Ontario)
"Ret Receptor Tyrosine Kinase Dysregulation In Tumorigenesis" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:35 pm | Leslie Gold (New York University)
"TGFβ, Estrogen And Progesterone Converge To Regulate Endometrial Cancer Growth" |
8:35 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Marja Nevalainen (Thomas Jefferson University)
"Autocrine Prolactin-Jak2-Stat5 Signaling Pathway In Growth Promotion Of Prostate Cancer" |
9:15 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | DEVELOPMENTAL PATHWAYS GONE AWRY IN CANCER |
| Discussion Leaders: Susan Kasper (Vanderbilt University) & Gail Prins (University of Illinois at Chicago) |
9:00 am - 9:05 am | Opening Comments |
9:05 am - 9:30 am | Kornelia Polyak (Harvard University)
"Breast Cancer Stem Cells And Tumorigenesis" |
9:30 am - 9:45 am | Discussion |
9:45 am - 10:10 am | Wade Bushman (University Wisconsin)
"Sonic Hedgehog Signaling In Prostate Development And Cancer" |
10:10 am - 10:25 am | Discussion |
10:25 am - 10:50 am | Coffee Break |
10:50 am - 11:15 am | Michael B. Major (University of North Carolina)
"Wnt Signaling During Development And Cancer" |
11:15 am - 11:30 am | Discussion |
11:30 am - 11:55 am | Sara Sukumar (Johns Hopkins University)
"Regulation And Roles Of Hox Genes In Breast Cancer" |
11:55 am - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | New Investigator Short Presentation: Caroline Ford (Lund University)
"The Wnt5a derived Foxy-5 Peptide Renders Insensitive Breast Cancer Cells Responsive to Tamoxifen" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session II |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting: Part I |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms) |
7:30 pm - 9:30 pm | ENVIRONMENTAL HORMONES: EFFECTS ON DEVELOPMENT AND CANCER |
| Discussion Leaders: Mike Gallo (Rutgers University) & John McLachlan (Tulane University) |
7:30 pm - 7:35 pm | Opening Comments |
7:35 pm - 8:00 pm | David Crews (University of Texas, Austin)
"Endocrine Disrupting Chemicals in Development" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:35 pm | Anna Soto (Tufts University)
"Developmental Basis Of Carcinogenesis: Early Life Exposure To Bisphenol A and Breast Neoplasia" |
8:35 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | John McLachlan (Tulane University)
"Signaling Pathways of Endocrine Disrupting Chemicals across the Animal Kingdom" |
9:15 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
8:45 am - 9:00 pm | Business Meeting: Part II |
| (Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
9:00 am - 12:30 pm | EPIGENOMIC MECHANISMS REGULATING DEVELOPMENT AND HORMONE-DEPENDENT CANCERS |
| Discussion Leaders: Shuk-mei Ho (University of Cincinnati) & Gerry Coetzee (Southern California University) |
9:00 am - 9:05 am | Opening Comments |
9:05 am - 9:30 am | John McCarrey (University of Texas, San Antonio)
"Epigenetic Regulation of Testis-Specific Gene Expression" |
9:30 am - 9:45 am | Discussion |
9:45 am - 10:10 am | Tim Huang (Ohio State University)
"DNA Methylation Of Breast Cancer Progenitor Cells by Estrogens" |
10:10 am - 10:25 am | Discussion |
10:25 am - 10:50 am | Coffee Break |
10:50 am - 11:15 am | Cheryl Walker (University of Texas; MD Anderson)
"Developmental Programming and Uterine Leiomyoma: Estrogen-induced Modulation of Histone Methyltransferase Activity" |
11:15 am - 11:30 am | Discussion |
11:30 am - 11:55 am | Ralph de Vere White (University of California, Davis)
"Induction Of Androgen-Independent Prostate Cancer Growth By An Androgen-Regulated microRNA" |
11:55 am - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | New Investigator Short Presentation: Yi-Wen Huang (Ohio State University)
"Epigenetic Repression of miRNA 129-2 leads to Overexpression of Sox4 Oncogene in Endometrial Cancer" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session II (continued) |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | NOVEL APPROACHES FOR TRANSLATIONAL RESEARCH |
| Discussion Leaders: Kevin White (University of Chicago) & Wade Bushman (University of Wisconsin) |
7:30 pm - 7:35 pm | Opening Comments |
7:35 pm - 8:00 pm | Randall Peterson (Harvard University)
"Small Molecule Screening With Zebrafish Embryos" |
8:10 pm - 8:20 pm | Discussion |
8:20 pm - 8:45 pm | Myles Brown (Dana-Farber, Harvard University)
"A Cistromes View of Hormone Dependence" |
8:45 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Suzanne A.W. Fuqua (Baylor College of Medicine)
"Novel Mechanisms Of Hormone Resistance" |
9:20 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |