Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: Career Development for Early Career Scientists
Discussion Leader: Rayzel Fernandes (Imperial College London, United Kingdom)
3:45 pm - 3:50 pm
Introduction by Discussion Leader
3:50 pm - 4:15 pm
Kornelia Polyak (Dana-Farber Cancer Institute, United States)
"Cancer as a Systemic Disease"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Understanding Early and Late-Stage Hormone-Dependent Cancers
Discussion Leader: Thomas Pulliam (MD Anderson Cancer Center, United States)
7:30 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:00 pm
Kiel Tietz (University of Minnesota, United States)
"Alternative Polyadenylation as a Therapeutic Vulnerability in Prostate Cancer"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:20 pm
Craig Rush (Huntsman Cancer Institute - University of Utah, United States)
"Progesterone and Estrogen Signaling Impact Each Other’s Transcriptional Activity in Endometrial Cancer"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Jacque Lyman (University of Minnesota, United States)
"Exploring Biomarkers in a Phase II Trial of Sacituzumab Govitecan in Advanced Prostate Cancer"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:00 pm
Maggie Musick (University of Colorado- Anschutz Medical Campus, United States)
"The Tumorigenic Effects of E-cadherin Loss in Early Breast Tumorigenesis"
9:00 pm - 9:10 pm
Discussion
9:10 pm - 9:20 pm
Hazel Quinn (ISREC-EPFL, Switzerland)
"Aiding and aBETting Metastasis: Epigenetic-Driven awakening in ER+ Breast Cancer"
9:20 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Dissecting the Interplay Between Cancer Development and the Tumor Microenvironment
Discussion Leader: Martin Sjöström (University of California, San Francisco, United States)
9:00 am - 9:20 am
Introduction by Discussion Leader
9:20 am - 9:30 am
Jiaxiang Tao (Georgetown University, United States)
"New Insights into the Pro-Oncogenic Effects of E1 in Obese Breast Adipocyte"
9:30 am - 9:40 am
Discussion
9:40 am - 9:50 am
Debjani Saha (Imperial College, London, United Kingdom)
"Towards Quantification of Cancer Adaptation: Developing a Platform to Study Transcriptional Changes in Single Cell in Real-Time (Single-Cell Biopsies)"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
John Fenimore (NIH, United States)
"Neoadjuvant Intense ADT for Locally Advanced Prostate Cancer Induces Heightened Immune Activity"
10:10 am - 10:20 am
Discussion
10:20 am - 10:30 am
Hannah Dewhurst (Imperial College London, United Kingdom)
"Single Lineage Fate Tracking and Targeted CRISPR Screening Towards the Identification of Dormancy Mediators in Luminal A Breast Cancer"
10:30 am - 10:40 am
Discussion
10:40 am - 10:50 am
Alana Arnone (Wake Forest School of Medicine, United States)
"Anti-Cancer Endocrine-Targeting Therapies and Diet Interactions Shift the Gut Microbiome to Impact ER+ Breast Carcinogenesis and Outcomes"
10:50 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Power of a PhD: Creating Impact During and After the Training
Discussion Leader: Moriah Cunningham (Thomas Jefferson University, United States)
1:30 pm - 2:30 pm
Panel Discussion
Mentorship and Career
Alyssa Flynn (Sanofi, United States)
Justin Hwang (University of Minnesota, United States)
Bob Riter (Cornell University, United States)
Lucas Brand (American Association for Cancer Research, United States)
Kornelia Polyak (Dana-Farber Cancer Institute, United States)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes
