Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: Unconventional Insulins
Discussion Leader: Aurelien CHUARD (Boston College, United States)
3:45 pm - 4:20 pm
Emrah Altindis (Boston College, United States)
"Viral Insulin/IGF-like Peptides and Their Unique Functions on Insulin/IGF System"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Insulin/IGF System in Evolution, Metabolism and Metabolic Diseases
Discussion Leaders: Mahya Shariat Razavi (New Mexico State University, United States) and Chloe Jang (western university, Canada)
7:30 pm - 7:55 pm
Na-Oh Yunn (Pohang University of Science and Technology, South Korea)
"Functional Selectivity of Insulin Receptor Revealed by Aptamer-trapped Receptor Structures"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:25 pm
Rahul Rajala (University of Oklahoma Health Sciences Center, United States)
"The Role of Endothelial PARs in Modulating Insulin Signaling"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:55 pm
Aurelien CHUARD (Boston College, United States)
"Insulin Goes Viral: The Role of Viral Insulin/IGF-1 Like Peptides in Host-virus Interactions"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:25 pm
YUSUF DOGRU (Boston College, United States)
"Evolution of Insulin, Insulin-like Growth Factors and Their Cognate Receptors in Vertebrates, Invertebrates and Viruses"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Insulin and IGFs in Growth, Development, Tissue Regeneration and Cancer
Discussion Leader: Na-Oh Yunn (Pohang University of Science and Technology, South Korea)
9:00 am - 9:20 am
Stephen O'Shea (University College Cork, Ireland) and Niamh McDermott (University College Cork, Ireland, Ireland)
"Phosphorylation of IGF-1R Tyr1250/1251 Regulates Receptor Activity and Cellular Phenotype"
9:20 am - 9:30 am
Discussion
9:30 am - 9:55 am
Yue (Helen) Zhang (Stanford University/HHMI, United States)
"Autocrine Insulin-like Growth Factor 2 Controls Self-renewal of Pulmonary Neuroendocrine Stem Cells"
9:55 am - 10:00 am
Discussion
10:00 am - 10:25 am
Jenica Kakadia (Western University, Canada)
"AMPK-mTORC1 Pathway Decreases IGF-1 Bioavailability in Glucose Deprivation: A Mechanism Restricting Fetal Growth"
10:25 am - 10:30 am
Discussion
10:30 am - 10:55 am
Christopher Galifi (Rutgers New Jersey Medical School, United States)
"Understanding the Unique Roles of the Insulin Receptor Isoforms in Breast Cancer"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Development Program for Students, Postdocs and Research Scientists
Discussion Leader: Bhumika Rajoria (University of Minnesota, United States)
1:30 pm - 2:30 pm
Panel Discussion
Ask the Scientist
Danny Chou (Stanford University, United States)
Emrah Altindis (Boston College, United States)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes