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| Sunday Afternoon | Arrival & Registration |
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| 6:00 | Dinner |
| Sunday Evening 7:30 to 10:00 PM | The Immunological Synapse |
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| Discussion Leader - Michael Dustin, Washington University, St. Louis |
| Speakers: |
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- Mike Dustin (Washington University)
Regulation of immunological synapse formation by chemokines.
- Peter Friedl (University of Wuerzburg)
Dynamics of antigen presentation - the serial encounter model.
- Bridget Wilson (University of New Mexico)
Microdomain organization of FceRI signaling.
- Avi Kupfer (National Jewish Medical and Research Center)
Multi-signal coordination by spatial-temporal assembly of SMACs
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| 10:30 | Refreshments |
| Monday Morning 9:00 AM to 12:00PM | Lymphocyte Fate during Development |
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| Discussion Leader - Michael Bevan, University of Washington, Seattle |
| Speakers: |
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- Antonius Rolink (Basel Institute for Immunology)
Plasticity of early haematopoietic precursor cells
- Harald von Boehmer (Harvard Medical School)
Constitutive Pre-T cell Receptor Signaling
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| 11:00 | Coffee Break |
- Freddy Radtke (Ludwig Institute for Cancer Research)
Notch1 and T Cell Development: Insights from Conditional Knockout Mice
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| Monday Afternoon | Poster Sessions |
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| 12:30 | Lunch |
| 4:00 to 6:00 | Poster Session |
| 6:00 | Dinner |
| Monday Evening 7:30 to 10:00 PM | Structural Insights into Immunological Mechanisms |
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| Discussion Leader - Ian A. Wilson (The Scripps Research Institute) |
| Speakers: |
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- Ian A. Wilson (The Scripps Research Institute)
TCR recognition of classical and non-classical MHC
- Roland Strong (Fred Hutchinson Cancer Research Center)
Crystal Structure of the Complex between the Stress-inducible MHC Class I Homolog MICA and the NK Cell Receptor NKG2D
- Steve Almo (Albert Einstein College of Medicine)
Structure of the CTLA-4/B7 costimulatory complex
- Peter D. Sun, Ph.D (National Institute of Allergy and Infectious Diseases)
Recognition of Class I MHC by NK cell Ig-like receptors
- Daved H. Fremont (Washington University School of Medicine)
Viral subversion of host chemokine networks
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| 10:30 | Refreshments |
| Tuesday Morning 9:00 AM to 12:00PM | Lymphocyte Fate: Homeostasis |
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| Discussion Leader - Philippa Marrack - National Jewish Medical and Research Center |
| Speakers: |
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- Rose Zamoyska (MRC, Mill Hill)
The role of TCR-mediated signals in T cell survival and homeostatic proliferation.
- Charlie Surh (Scripps Research Institute)
Regulation of naive T cell homeostasis
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| 10:30 | Coffee Break |
- Rafi Ahmed (Emory University)
Memory CD8 T cells
- Pippa Marrack (National Jewish Medical and Research Center)
Counting memory cells.
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| Tuesday Afternoon | Poster Sessions |
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| 12:30 | Lunch |
| 4:00 to 6:00 | Poster Session |
| 6:00 | Dinner |
| Tuesday Evening 7:30 to 10:00 PM | Recognition by Non-rearranging Receptors |
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| Discussion Leader - David Raulet - Universty of California at Berkeley |
| Speakers: |
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- Ruslan Medzhitov (Yale University)
Role of Toll-like Receptors in Immune Recognition
- David Raulet (University of California at Berkeley)
The NKG2D-ligand system: A new component of the innate immune system
- Eric Vivier (CNRS de Marseille Luminy)
Control of hematopoieitic cell functions by ITIM-bearing receptors and their activating counterparts
- Valerie Fadok (National Jewish medical and Research Center)
Apoptosis, inflammation, and tissue homeostasis: A role for the phosphatidylserine-specific receptor
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| 10:30 | Refreshments |
| Wednesday Morning 9:00 AM to 12:00PM | Lymphocyte Fate: Interactions with Antigen |
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| Discussion Leader - Marc Jenkins - University of Minnesota |
| Speakers: |
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- Antonio Lanzavecchia (Institute for Research in Biomedicine)
Generation and maintenance of effector and memory T cells
- Marc Jenkins (University of Minnesota)
Visualizing the generation of memory CD4 T cells in the whole body during a primary immune response
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| 10:30 | Coffee Break |
- Anne O'Garra (DNAX Research Institute)
In vitro generation of regulatory T cells using a combination of immunosuppressive drugs
- Mark Shlomchik (Yale University)
Activation and maintenance of autoreactive and memory B cells
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|
| 12:30 | Lunch |
| 6:00 | Dinner |
| Wednesday Evening 7:30 to 10:00 PM | Vesicle Trafficking |
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| Discussion Leader - Ira Mellman - Yale University |
| Speakers: |
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- Ira Mellman (Yale University)
Generation and maintenance of cell polarity
- Sandra Schmid (Scripps Research Institute)
Hsc70 mutants disrupt the clathrin-coated vesicle cycle in vivo
- Graham Warren (Yale University)
Biogenesis of the Golgi complex.
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| 10:30 | Refreshments |
| Thursday Morning 9:00 AM to 12:00PM | Control of Ig Gene Expression |
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| Discussion Leader - Ursula Storb - University of Chicago |
| Speakers: |
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- Ursula Storb (University of Chicago )
Expression and somatic hypermutation of Ig genes
- David Roth (Baylor College of Medicine)
Biochemical analysis of V(D)J recombination
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| 10:30 | Coffee Break |
- Ming Tian (Harvard Medical School)
Transcription-induced cleavage of immunoglobulin switch regions by nucleotide excision repair nucleases
- Fotini Papavasiliou (Rockefeller University)
DNA double strand breaks and the mechanism of somatic hypermutation
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|
| 12:30 | Lunch |
| 6:00 | Banquet |
| Thursday Evening 7:30 to 10:00 PM | T cell regulation: Suppression Revisited |
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| Discussion Leader - Ethan Shevach - National Institute of Allergy and Infectious Diseases |
| Speakers: |
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- Juan J. Lafaille (New York University Medical Center)
Regulatory T cells in spontaneous EAE
- Megan Levings (San Raffaele Telethon Institute)
Tr1 Cells
- Ethan Shevach (National Institute of Allergy and Infectious Diseases)
Control of T cell activation by CD4+CD25+ T cells
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| 10:30 | Refreshments |
