Sunday |
4:00 pm - 8:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Keynote Session: Innate Sensors |
| Discussion Leader: Ronald Germain (National Institute of Allergy and Infectious Diseases, NIH, USA) |
7:40 pm - 8:20 pm | Max Cooper (Emory University School of Medicine, USA) "Evolution of Lymphocyte-Mediated Adaptive and Innate Immunity" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Caetano Reis e Sousa (The Francis Crick Institute / Cancer Research UK, United Kingdom) "Innate Sensing of Damage and Infection" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Marion Pepper (University of Washington, USA) "Somatically Mutated IgM Memory B Cells Respond Rapidly upon Secondary Plasmodium Infection" |
9:20 pm - 9:30 pm | Discussion |
Monday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Myeloid Cell Development and Gene Regulation |
| Discussion Leader: John Wherry (University of Pennsylvania, USA) |
9:00 am - 9:20 am | Miriam Merad (Icahn School of Medicine at Mount Sinai, USA) "Macrophages
in the Control of Tissue Homeostasis" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Edward Pearce (Washington University School of Medicine in St. Louis, USA) "Metabolic Control of Antigen Presenting Cells" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Ken Murphy (Washington University School of Medicine in St. Louis, USA) "Origin and Function of Dendritic Cells" |
10:20 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:20 am | Gioacchino Natoli (IEO - European Institute of Oncology, Italy) "Transcriptional Control in Inflammation and Cancer" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:40 am | Niroshana Anandasabapathy (Harvard Medical School, USA) "Homeostatic Monophagocyte Signatures Limit Anti-Tumor Immunity" |
11:40 am - 11:45 am | Discussion |
11:45 am - 11:55 am | Biana Bernshtein (Weizmann Institute of Science, Israel) "Studying Communication Circuits of Intestinal Macrophages and Their Environment in the Healthy and Inflamed Gut" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Janneke van Blijswijk (The Francis Crick Institute, United Kingdom) "Fate Mapping of Single Dendritic Cell Precursors in Tissues" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:30 pm | Free Time |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm - 8:00 pm | Transcriptional and Post-Transcriptional Regulation of Lymphocytes |
| Discussion Leader: Federica Sallusto (Institute for Research in Biomedicine, Università della Svizzera Italiana, Switzerland) |
6:00 pm - 6:20 pm | Vigo Heissmeyer (Ludwig Maximilian University of Munich, Germany) "Post-Transcriptional Control of T Cell Differentiation by RNA Binding Proteins" |
6:20 pm - 6:30 pm | Discussion |
6:30 pm - 6:50 pm | John O'Shea (National Institutes of Health, USA) "Epigenetic Control of Adaptive Immunity" |
6:50 pm - 7:00 pm | Discussion |
7:00 pm - 7:20 pm | Sasha Rudensky (Memorial Sloan Kettering Cancer Center, USA) "Transcription Control of Regulatory T Cells" |
7:20 pm - 7:30 pm | Discussion |
7:30 pm - 7:50 pm | Evan Newell (Singapore Immunology Network, Singapore) "High Dimensional Approaches for Identifying and Characterizing Tumor Specific T Cells" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm | Dinner |
Tuesday |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Immune Networks |
| Discussion Leader: Caetano Reis e Sousa (The Francis Crick Institute / Cancer Research UK, United Kingdom) |
9:00 am - 9:20 am | Ronald Germain (National Institute of Allergy and Infectious Diseases, NIH, USA) "Imaging the Immune System" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Facundo Batista (The Francis Crick Institute / Cancer Research UK, United Kingdom) "Control of B Cell Responses" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Philippe Bousso (Institut Pasteur, France) "Decoding Immune Responses to Cancer and Infection Using In Vivo Imaging" |
10:20 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:15 am | Muzlifah Haniffa (Newcastle University, United Kingdom) "Human Dendritic Cell Diversity" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:40 am | Fiona Powrie (The Kennedy Institute of Rheumatology, University of Oxford, United Kingdom) "Mucosal Inflammation: From IBD to Colon Cancer" |
11:40 am - 11:50 am | Discussion |
11:50 am - 12:05 pm | Michela Locci (La Jolla Institute for Allergy and Immunology, USA) "Activin A Orchestrates the Gene Program of Human T Follicular Helper Cells" |
12:05 pm - 12:10 pm | Discussion |
12:10 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:30 pm | Free Time |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm - 8:00 pm | Primary and Memory Responses |
| Discussion Leader: Antonio Lanzavecchia (Institute for Research and Biomedicine, Università della Svizzera Italiana, Switzerland) |
6:00 pm - 6:20 pm | Sebastian Amigorena (Curie Institute, France) "Immunity and Cancer" |
6:20 pm - 6:30 pm | Discussion |
6:30 pm - 6:50 pm | Federica Sallusto (Institute for Research in Biomedicine, Università della Svizzera Italiana, Switzerland) "Functional Heterogeneity of Human Memory CD4+ T Cell" |
6:50 pm - 7:00 pm | Discussion |
7:00 pm - 7:20 pm | Dirk Busch (Technische Universität München, Germany) "Stemness of CD8(+) Central Memory T Cells" |
7:20 pm - 7:30 pm | Discussion |
7:30 pm - 7:40 pm | Robert Kimmerling (Massachusetts Institute of Technology, USA) "Linking Gene Expression and Phenotype in Single CD8+ T Cells" |
7:40 pm - 7:45 pm | Discussion |
7:45 pm - 7:55 pm | Chloe Slichter (Fred Hutchinson Cancer Research Center, USA) "Distinct Activation Thresholds of Human Conventional and Innate-Like Memory T Cells" |
7:55 pm - 8:00 pm | Discussion |
8:00 pm | Dinner |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Host-Microbe Interactions |
| Discussion Leader: Yasmine Belkaid (National Institute of Allergy and Infectious Diseases, NIH, USA) |
9:00 am - 9:20 am | Akiko Iwasaki (Yale School of Medicine, USA) "Anti-Viral Tissue Immunity" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Kenya Honda (Keio University School of Medicine / RIKEN, Japan) "Regulation of T Cells by the Gut Microbiota" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Eric Pamer (Memorial Sloan-Kettering Cancer Center, USA) "Antimicrobial Resistance: Role of the Microbiota" |
10:20 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:20 am | Eran Elinav (Weizmann Institute of Science, Israel) "Host Microbiome Interactions in Health and Diseases" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:40 am | Teresa Ai (Washington University in St. Louis, USA) "The Role of Type 1 Inflammation in Modulating Colonic Regulatory T Cells Specific to Commensal Bacteria" |
11:40 am - 11:45 am | Discussion |
11:45 am - 11:55 am | Thomas Ciucci (National Cancer Instititute, NIH, USA) "Memory Fate Is Imprinted in CD4+ T-Cells by a Thpok-Dependent Transcriptional Program" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Eduardo Villablanca (Karolinska Institutet, Sweden) "Retinoic Acid Receptor Alpha in Epithelial Cells Controls Global Intestinal Immunological Fitness" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:30 pm | Free Time |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm - 8:00 pm | Interventions and Monitoring in Vaccination |
| Discussion Leader: Sebastian Amigorena (Curie Institute, France) |
6:00 pm - 6:20 pm | Mark Davis (Stanford University School of Medicine, USA) "Human Immunology" |
6:20 pm - 6:30 pm | Discussion |
6:30 pm - 6:50 pm | Peter Kwong (Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, USA) "Structure-Based Vaccine Design" |
6:50 pm - 7:00 pm | Discussion |
7:00 pm - 7:20 pm | Antonio Lanzavecchia (Institute for Research and Biomedicine, Università della Svizzera Italiana, Switzerland) "A New Mechanism of Antibody Diversification" |
7:20 pm - 7:30 pm | Discussion |
7:30 pm - 7:40 pm | Michelle Krogsgaard (New York University School of Medicine, USA) "Constitutive Lck Activity Drives Sensitivity Differences Between CD8+ Memory T Cell Subsets" |
7:40 pm - 7:45 pm | Discussion |
7:45 pm - 7:55 pm | Gregory Szeto (University of Maryland, Baltimore County, USA) "Cytokine Signatures Enable Predictive Models of Efficacy in Cancer Immunotherapy" |
7:55 pm - 8:00 pm | Discussion |
8:00 pm | Dinner |
Thursday |
7:30 am - 8:30 am | Breakfast |
8:30 am - 9:00 am | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
9:00 am - 12:30 pm | Cytokines and Tissue Responses |
| Discussion Leader: Miriam Merad (Icahn School of Medicine at Mount Sinai, USA) |
9:00 am - 9:20 am | Burkhard Becher (University of Zurich, Switzerland) "How T Cells Instruct Myeloid Cells in Autoimmunity" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Bana Jabri (University of Chicago, USA) "Pathogenesis of Celiac Disease" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:40 am | Coffee Break |
10:40 am - 11:00 am | Matteo Iannacone (San Raffaele Hospital, Italy) "Immunosurveilance in the Liver" |
11:00 am - 11:10 am | Discussion |
11:10 am - 11:25 am | Tatyana Chtanova (Garvan Institute of Medical Research, Australia) "Tumour-Conditioned Immune Cells Exit Tumours to Provide Effector Function in Draining Lymph Nodes" |
11:25 am - 11:30 am | Discussion |
11:30 am - 11:45 am | Vinidhra Mani (Harvard University, USA) "Mapping TGF-β Signaling Dynamics in CD8+ Skin TRM Differentiation" |
11:45 am - 11:50 am | Discussion |
11:50 am - 12:05 pm | Janet Markle (The Rockefeller University, USA) "Inborn Errors of Human IL-12 or IL-23 Impair IFN-γ Immunity and Underlie Mycobacterial Disease" |
12:05 pm - 12:10 pm | Discussion |
12:10 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:30 pm | Free Time |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm - 8:00 pm | Microenvironment and Immunotherapy in Cancer and Chronic Infections |
| Discussion Leader: Akiko Iwasaki (Yale School of Medicine, USA) |
6:00 pm - 6:10 pm | Introduction by Discussion Leader |
6:10 pm - 6:30 pm | Andrea Ablasser (Global Health Institute, Ecole Polytechnique Federale de Lausanne, Switzerland) "Intracellular DNA Sensing During Pathogen Infection and Beyond" |
6:30 pm - 6:40 pm | Discussion |
6:40 pm - 7:00 pm | John Wherry (University of Pennsylvania, USA) "Immune Exhaustion During Infection and Cancer" |
7:00 pm - 7:10 pm | Discussion |
7:10 pm - 7:30 pm | Dietmar Zehn (Technical University of Munich, Switzerland) "T Cell Subset Diversification in Chronic Infections" |
7:30 pm - 7:40 pm | Discussion |
7:40 pm - 8:00 pm | General Discussion |
8:00 pm | Dinner |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |