Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Modulating Immunity for Human Health
Discussion Leaders: Susan Thomas (Georgia Institute of Technology, United States) and Madhav Dhodapkar (Emory University School of Medicine, United States)
7:40 pm - 7:50 pm
Opening Remarks
7:50 pm - 8:25 pm
Darrell Irvine (Massachusetts Institute of Technology, United States)
"Engineering Immunity in Cancer and Infectious Disease"
8:25 pm - 8:40 pm
Discussion
8:40 pm - 9:15 pm
Melody Swartz (University of Chicago, United States)
"Engineering Drug Delivery to the Immune System"
9:15 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Growth Areas in Immunology: Human Immunity
Discussion Leaders: Anna Blakney (University of British Columbia, Canada)
9:00 am - 9:30 am
Mark Davis (Stanford University School of Medicine, United States)
"Models of Human Immunity"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
Marco Colonna (Washington University School of Medicine, United States)
"Innate Immunity in Neurodegeneration and Autoimmunity"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:15 am
Onyinye Iweala (University of North Carolina at Chapel Hill, United States)
"Alpha-gal Syndrome : Pushing the Envelope in the Food Allergy"
11:15 am - 11:25 am
Discussion
11:25 am - 11:40 am
Kaitlyn Sadtler (National Institutes of Health, United States)
"Tracking Undiagnosed SARS-CoV-2 in the United States through Population-Level Serosurveys"
11:40 am - 11:50 am
Discussion
11:50 am - 12:05 pm
Erika Moore (University of Florida, United States)
"Considering Ancestry in Immune Heterogeneity"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizers: Erika Moore (University of Florida, United States) and Jai Rudra (Washington University in St Louis, United States)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Systems and Computational Immunology
Discussion Leader: Kathryn Miller-Jensen (Yale University, United States)
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 8:05 pm
Christina Leslie (Memorial Sloan Kettering Cancer Center, United States)
"Human Cell Atlas From Single Cell Genomics"
8:05 pm - 8:20 pm
Discussion
8:20 pm - 8:50 pm
Paul Macklin (Indiana University Bloomington, United States)
"Computational Models of Immune Dynamics"
8:50 pm - 9:05 pm
Discussion
9:05 pm - 9:20 pm
Maral Budak (University of Michigan, United States)
"A Systems Biology Approach to Identify Improved Regimens for Tuberculosis Treatment"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Molecularly Engineered Immunotherapies
Discussion Leader: Johnny Blazeck (Georgia Tech, United States)
9:00 am - 9:30 am
Mariana Kaplan (National Institutes of Health/NIAMS, United States)
"Targeting Innate Immune Responses in Systemic Autoimmunity"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
George Georgiou (University of Texas, Austin, United States)
"Engineering Enzyme and Antibody Therapeutics"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
Janine Schuurman (Genmab, The Netherlands)
"Bispecific and Effector-Function Enhanced Antibody Therapies"
11:30 am - 11:45 am
Discussion
11:45 am - 12:00 pm
Omid Veiseh (Rice University, United States)
"Clinically Translatable Cytokine Factories for Cancer Immunotherapy"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
In Vitro Models of Immunity
Discussion Leader: Monica Moya (Lawrence Livermore National Laboratory, United States)
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 8:05 pm
Linda Griffith (Massachusetts Institute of Technology, United States)
"Engineered Models of Inflammatory Disease"
8:05 pm - 8:20 pm
Discussion
8:20 pm - 8:50 pm
Nancy Allbritton (University of Washington, United States)
"A Microscale Colon with Mucus, Microbes and Immune cells"
8:50 pm - 9:05 pm
Discussion
9:05 pm - 9:20 pm
Laurel Hind (University of Colorado Boulder, United States)
"An Infection-on-a-Chip for Evaluating Immune Responses"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Biomaterials for Vaccines and Immunomodulation
Discussion Leader: Jamal Lewis (University of Florida, United States)
9:00 am - 9:30 am
Edward Botchwey (The Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University , United States)
"Materials for Immunomodulation of Wound Healing In Vivo"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
Suzie Pun (University of Washington, United States)
"Bio-Inspired Materials for Drugging of T Cells and Macrophages"
10:15 am - 10:30 am
Discussion
10:30 am - 10:55 am
Coffee Break
10:55 am - 11:25 am
David Mooney (Harvard University, United States)
"Biomaterials for Immunomodulation"
11:25 am - 11:40 am
Discussion
11:40 am - 11:55 am
Benjamin Keselowsky (University of Florida, United States)
"Galectin-Anchored Indoleamine 2,3-Dioxygenase Suppresses Local Inflammation"
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:20 pm
Eric Appel (Stanford University, United States)
"Harnessing Sustained Release to Produce Robust, Durable, and High-Quality Humoral Immunity"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
7:30 pm - 9:30 pm
Enabling Technologies to Assess Immune Cell Function
Discussion Leader: Armon Sharei (SQZ Biotechnologies, United States)
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 8:05 pm
Daniel Irimia (Harvard Medical School, United States)
"Ex Vivo, Microfluidic Assays for CAR-T Lymphocyte and Human Neutrophil Functions
"
8:05 pm - 8:20 pm
Discussion
8:20 pm - 8:50 pm
Junsang Doh (Seoul National University, South Korea)
"Micro-Fabricated Platforms for Lymphocyte Biology"
8:50 pm - 9:05 pm
Discussion
9:05 pm - 9:20 pm
Jenny Jiang (University of Pennsylvania, United States)
"High-Throughput and High-Dimensional Single Cell Analysis of Antigen-Specific T cells"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Cellular Immunoengineering
Discussion Leader: Elizabeth Wayne (Carnegie Mellon University, United States)
9:00 am - 9:30 am
Wilson Wong (Wilson Wong, Associate Professor, Boston University, United States)
"Synthetic Biology for Immunotherapy"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
Yvonne Chen (University of California, Los Angeles, United States)
"Engineering Cancer-Fighting T Cells with Synthetic Biology"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
Krishnendu Roy (Georgia Tech, United States)
"Scalable, Quality-by-Design Driven Manufacturing of Immune Cell Therapies"
11:30 am - 11:45 am
Discussion
11:45 am - 12:00 pm
Li Tang (EPFL, Switzerland)
"Metabolically Armored CAR-T Cells Counter Dysfunction and Promote Stemness for Solid Tumor Clearance"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
New Frontiers: Spatially Resolved Analysis for Immunology
Discussion Leader: Kara Spiller (Drexel University, United States)
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 8:05 pm
Deborah Fowell (Cornell University, United States)
"Intravital Multiphoton Microscopy Uncovers Spatially-Distinct Activation Niches in Inflamed and Infected Tissues"
8:05 pm - 8:20 pm
Discussion
8:20 pm - 8:35 pm
Jessica Lancaster (Mayo Clinic, United States)
"Age-Associated Changes to the Lymph Node Microenvironment Impair T cell Motility and Response"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 9:15 pm
John Hickey (Stanford University, United States)
"Multiplexed Imaging and Multiscale Modeling Reveal ex Vivo T Cell Phenotype Drives Tissue Restructuring Necessary for T Cell Survival and Tumor Control"
9:15 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure