Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Organization of GABAergic Microcircuits in the Hippocampus
Discussion Leader: Andor Domonkos (Institute of Experimental Medicine, Hungarian Academy of Sciences, Hungary)
3:45 pm - 4:20 pm
Ivan Soltesz (Stanford University, USA)
"Organization of GABAergic Microcircuits in the Hippocampus"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Molecular, Synaptic and Sub-Synaptic Dynamics of Inhibition
Discussion Leader: Ingie Hong (Johns Hopkins Medical Institute, USA)
7:30 pm - 7:50 pm
Anna Nathanson (Tufts University, USA)
"An Amino Acid Motif Within the GABA-A Receptor a2 Subunit Promotes Inhibitory Synaptogenesis and Seizure Resilience"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Paul Anastasiades (New York University, USA)
"Thalamus-Evoked Inhibition Mediates Precise Cellular and Sub-Cellular Control of Prefrontal Projection Neurons"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Clémence Bernard (King's College London, United Kingdom)
"Local Control of Protein Synthesis for Cortical Inhibitory Wiring"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Max Joffe (Vanderbilt University, USA)
"Acute Stress Usurps mGlu5-Driven Plasticity on Somatostatin Interneurons to Facilitate Bottom-up Processing in the Prefrontal Cortex"
9:20 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Inhibitory Neurons in Circuits, Networks and Behavior
Discussion Leader: Antonio Fernandez-Ruiz (Neuroscience Institute, New York University, USA)
9:00 am - 9:20 am
James Maksymetz (Vanderbilt University, USA)
"mGlu1 Potentiation Enhances Prefrontal Cortical Inhibition via Somatostatin-Expressing Interneurons and Rescues Schizophrenia-Like Behavioral Deficits"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Emily Jones (University of California, San Francisco, USA)
"Hippocampal GABAergic Interneurons Bi-Directionally Modulate Sharp-Wave Ripples"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Adam Caccavano (Georgetown University Medical Center, USA)
"Determining Mechanisms Underlying Hippocampal Network Disruption in Early Amyloid Pathology: The Role of PV+ Cells on Sharp-Wave Ripples"
10:20 am - 10:30 am
Discussion
10:30 am - 10:50 am
Wen-Hsien Hou (Aarhus University, Denmark)
"Role of Nitric Oxide Synthase-Expressing GABAergic Neurons of the Mouse Amygdala on Sleep"
10:50 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Non-Traditional Roles of Inhibition
Discussion Leader: Jiaxing Li (Oregon Health & Science University, USA)
1:30 pm - 1:50 pm
Lida Zoupi (University of Edinburgh, United Kingdom)
"Loss of Inhibitory Interneurons and Synaptic Alterations in Multiple Sclerosis"
1:50 pm - 2:00 pm
Discussion
2:00 pm - 2:20 pm
Sara Mederos (Instituto Cajal, CSIC, Spain)
"PV+-Astrocyte Signaling Modulates Cortical Inhibitory Synaptic Activity"
2:20 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
