Integrating Physics and Biology From Development to Disease

Intermediate filaments form cytosolic or nuclear networks that support cell shape and function. Each cell type in the body expresses a combination of cell-type specific intermediate filament proteins that changes during development and in disease. Mutations in genes encoding intermediate filaments and changes in intermediate filament composition are causal to or associated with many diseases, from degenerative striated muscle and brain diseases to inflammatory diseases, skin diseases, and various cancers.

This Gordon Research Conference (GRC) brings together researchers from a broad range of disciplines to highlight recent advances and new approaches relevant to the intermediate filament field. The GRC is instrumental in initiating new ideas and collaborations, deepening the understanding of the physics and biology of intermediate filaments, and unraveling their role in cell physiology and diseases. With the GRC and the accompanying Gordon Research Seminar (GRS), we aim to recruit and promote talented early-stage and established new investigators into the intermediate filament field, providing them with cutting-edge scientific presentations, mentorship, and networking opportunities. We invite scientists from cell biology, biophysics, mechanobiology, biomedical engineering, and translational and clinical research to attend this meeting to apply their expertise and stimulate their interest in intermediate filament biology.