Saturday
1:30 pm - 4:30 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm
Keynote Session: Ways and Means to Resolve the Structure of IFs
Discussion Leader: Clarissa Koch (Northwestern University, USA)
3:15 pm - 3:45 pm
Ohad Medalia (University of Zurich, Switzerland)
"Ways and Means to Resolve the Structure of IFs"
3:45 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Intermediate Filaments: To the Cell Membrane and Beyond
Discussion Leader: Marcin Moch (University Hospital, RWTH Aachen University, Germany)
5:30 pm - 5:45 pm
Jessy van Asperen (University Medical Center Utrecht, Utrecht University, The Netherlands)
"Dissecting the Function of GFAP Isoforms in a 3D Organotypic Brain Slice Model of Astrocytoma Invasion"
5:45 pm - 5:50 pm
Discussion
5:50 pm - 6:05 pm
Justin Jacob (Johns Hopkins Bloomberg School of Public Health, USA)
"Keratin 17: A Novel Regulator of Nuclear Morphology and Chromatin Organization"
6:05 pm - 6:10 pm
Discussion
6:10 pm - 6:25 pm
Ana Laly Aguedo (Blizard Institute, Barts and the London, Queen Mary University of London, United Kingdom)
"The Keratin Cytoskeleton as a Regulator of Keratinocyte Mechano-Sensing"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:45 pm
Emma van Bodegraven (Brain Center Rudolf Magnus, UMC Utrecht, The Netherlands)
"GFAP Alternative Splicing in Astrocytoma Is Associated with Laminin-Induced MAPK-Signaling"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:05 pm
Brian Russo (Massachusetts General Hospital, USA)
"Intermediate Filaments Activate a Bacterial Secretion System"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
Nicole Schwarz (RWTH Aachen University, Germany)
"Determinants of Intermediate Filament Dynamics In Vivo "
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Zooming In: The Intricate Details of Intermediate Filament Biology
Discussion Leader: Brian Russo (Massachusetts General Hospital, USA)
9:00 am - 9:15 am
Konstantinos Tsilafakis (Biomedical Research Foundation, Academy of Athens, Greece)
"Unraveling the Unique Role of Desmin's Head Domain in Intermediate Filament Structure and Function"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Alvaro Viedma (Centro de Investigaciones Biologicas (CIB), CSIC, Spain)
"The Cysteine Residue of Glial Fibrillary Acidic Protein Is a Critical Target for Lipoxidation and Required for Efficient Network Formation"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Arun Venu (Åbo Akademi University, Finland)
"Vimentin's Role in Directional Cell Migration via Focal Adhesion Complex Modulation"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Sonja Lehmann (Institute of Molecular and Cellular Anatomy, RWTH Aachen University, Germany)
"Automated Tracking of Keratin Granules Reveals Effect of Non-Muscle Myosin II on Granule Motility"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Rachel Battaglia (University of North Carolina at Chapel Hill School of Medicine, USA)
"Functional Crosstalk Between Phosphorylation and Caspase Proteolysis Underlie Aberrant Processing of GFAP in Alexander Disease and Reveal CK2 as a Novel Disease Target"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Margarita Sobol (Institute of Molecular Genetics of the ASCR, v. v. i., Czech Republic)
"Advanced Microscopy Characterization of Nuclear Lipid Islets Which Participate in Forming Nuclear Architecture Competent for Transcription"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Panel
Discussion Leader: Oscar Stassen (Eindhoven University of Technology, The Netherlands)
1:30 pm - 2:30 pm
Panel Discussion
The Stories Behind the CV
John Eriksson (Turku Centre for Biotechnology / University of Turku / Åbo Akademi University, Finland)
Jan Lammerding (Cornell University, USA)
Franziska Lautenschlaeger (Leibniz Institute for New Materials, Germany)
Natasha Snider (University of North Carolina at Chapel Hill, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
