Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Imaging and Computing Intermediate Filament Functions in Living Cells
Discussion Leader: Amir Vahabikashi (Northwestern University, United States)
3:45 pm - 4:15 pm
Gaudenz Danuser (University of Texas Southwestern Medical Center, United States)
"Imaging and Computing Intermediate Filament Functions in Living Cells"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Intermediate Filaments: Structure and Mechanism
Discussion Leader: Subarna Dutta (University of Calcutta & Theomics International Private Limited, India)
7:30 pm - 7:45 pm
Tom Golde (Institut de Bioenginyeria de Catalunya, Spain)
"The Role of Intermediate Filaments in Stress Resistance in 3D Epithelial Structures"
7:45 pm - 7:55 pm
Discussion
7:55 pm - 8:10 pm
Pieter-Jan Vermeire (KU Leuven, Belgium)
"Novel Insights in IF Assembly by Chemical Cross-Linking Mass Spectrometry"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:35 pm
Navaneetha Krishnan Bharathan (The Pennsylvania State University, United States)
"Structure of a Novel Endoplasmic Reticulum-Desmosome-Keratin Complex and its Role in Skin Disease"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 9:00 pm
Ellen Gregory (University of California, Davis, United States)
"Disease-Associated Lamin Missense Mutations Lead to Nuclear Mispositioning, Micronuclei, and Swimming Defects in C. Elegans"
9:00 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Amir Vahabikashi (Northwestern University, United States)
"Nuclear Lamin Isoforms Differentially Contribute to LINC Complex-Dependent Nucleocytoskeletal Coupling and Whole Cell Mechanics"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Intermediate Filaments in Health and Disease
Discussion Leader: Claira Sohn (UT Health San Antonio, United States)
9:00 am - 9:15 am
Linghai Kong (UW-Madison, United States)
"GFAP Interacts With and Regulates Vesicular Trafficking and Secretion in Human Astrocytes"
9:15 am - 9:25 am
Discussion
9:25 am - 9:40 am
Martin Svoren (Radboud University Medical Center, The Netherlands)
"Impact of Lamin-Mediated Nuclear Deformability on Cancer Invasion and Metastasis In Vivo"
9:40 am - 9:50 am
Discussion
9:50 am - 10:05 am
Christopher Pineda (University of Michigan, United States)
"Role of Keratin 17 in DNA Damage Response and Tumorigenesis"
10:05 am - 10:15 am
Discussion
10:15 am - 10:30 am
Yang Xu (University of Michigan, United States)
"Keratin 17-Dependent Signals Impact Keratinocyte-Neutrophil Crosstalk in Inflamed Skin"
10:30 am - 10:40 am
Discussion
10:40 am - 10:55 am
Giulia Sultana (Abo Akademi- John Eriksson Lab, Finland)
"Vimentin Modulates the YAP-THROMBOSPONDIN-1 AXIS To Promote Wound Healing"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Steps to a Successful Career: Ask the Group Leaders
Discussion Leaders: Noam Zuela - Sopilniak (Cornell University, United States) and Šárka Salajková (University of Zurich, Switzerland)
1:30 pm - 2:30 pm
Panel Discussion
Mentorship
Giulio Agnetti (Johns Hopkins University School of Medicine, United States)
Pascale Bomont (Inserm - NeuroMyoGene institute (INMG), France)
Ming Guo (Massachusetts Institute of Technology, United States)
Karen Ridge (Northwestern University, United States)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes