Saturday |
1:30 pm - 4:30 pm | Arrival and Check-in |
3:00 pm - 3:15 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:15 pm - 4:00 pm | Characterizing IDPs by Computational Approaches |
| Discussion Leaders: M. Madan Babu (MRC Laboratory of Molecular Biology, United Kingdom) and Shrutidhara Biswas (Indian Institute of Technology Guwahati, India) |
3:15 pm - 3:30 pm | Alex Holehouse (Washington University in St. Louis, USA) "The Sequence Determinants of Phase Separation via Complex Coacervation in IDPs" |
3:30 pm - 3:35 pm | Discussion |
3:35 pm - 3:50 pm | Mainak Guharoy (VIB, Vrije Universiteit Brussel, Belgium) "The Tripartite Degron Model: Structural Disorder in the Control of Cellular Networks by Programmed Protein Degradation" |
3:50 pm - 4:00 pm | Discussion |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | Redefining the Structure-Function Paradigm |
| Discussion Leaders: Assaf Friedler (The Hebrew University of Jerusalem, Israel) and Cesar Cuevas-Velazquez (Universidad Nacional Autónoma de México, Mexico) |
5:30 pm - 5:50 pm | Eleanor Dickinson (University of Manchester, United Kingdom) "Let's Twist Again: Modulation of p53 N-Terminal Structure and Function with Varying Helicity" |
5:50 pm - 6:00 pm | Discussion |
6:00 pm - 6:20 pm | Ana Melo (University of Pennsylvania, USA) "Exploring the Conformational Plasticity of Tau: Insights into Function and Dysfunction" |
6:20 pm - 6:30 pm | Discussion |
6:30 pm - 6:50 pm | Kaitlyn Gerhart (Georgetown University, USA) "Self-Interaction of the Intrinsically Disordered c-Myc Oncoprotein" |
6:50 pm - 7:00 pm | Discussion |
7:00 pm - 7:20 pm | Eric Gibbs (Pennsylvania State University, USA) "Investigating the Structural Basis for the CTD Code" |
7:20 pm - 7:30 pm | Discussion |
8:00 pm | Dinner |
Sunday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | Exploring the Functional Diversity of IDPs |
| Discussion Leaders: Ashok Deniz (The Scripps Research Institute, USA) and Iker Valle Aramburu (European Molecular Biology Laboratory (EMBL), Germany) |
9:00 am - 9:20 am | Virginia Burger (Massachusetts Institute of Technology, USA) "A Bacterial Antitoxin's Conformational Ensemble Provides Insight into Distinct Functional Roles of Its Distinct Disordered States" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Erik Martin (St. Jude Children's Research Hospital, USA) "Sequence Determinants of the Conformational Properties of an Intrinsically Disordered Protein Prior to and Upon Multi-Site Phosphorylation" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Anne Bremer (Max Planck Institute of Molecular Plant Physiology, Germany) "Structural and Functional Characterization of Three Closely Related Intrinsically Disordered LEA Proteins from Arabidopsis thaliana" |
10:20 am - 10:30 am | Discussion |
10:30 am - 10:50 am | Shana Elbaum (Princeton University, USA) "From Fluids to Fibers: Liquid Phase Separation and Aggregation of Disordered Proteins" |
10:50 am - 11:00 am | Discussion |
11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:30 pm | Mentorship Component: Career Panel |
| Discussion Leader: K. Aurelia Ball (University of California, San Francisco, USA) |
1:30 pm - 2:30 pm | Panel Discussion |
| "Careers in Scientific Research" |
|
- Monika Fuxreiter (University of Debrecen, Hungary)
- Elizabeth Rhoades (University of Pennsylvania, USA)
- Philipp Selenko (FMP Berlin, Germany)
|
2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
3:00 pm | Seminar Concludes |