Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm
IDPs from Theory to Design
Discussion Leader: Mikael Garabedian (University of Pennsylvania, United States)
3:15 pm - 3:35 pm
Jasmine Cubuk (Washington University in St. Louis, United States)
"Single-Molecule Spectroscopy of the SARS-CoV-2 Nucleocapsid Protein"
3:35 pm - 3:40 pm
Discussion
3:40 pm - 3:55 pm
Sheung Chun Ng (Max Planck Institute for Multidisciplinary Sciences, Germany)
"Biophysical Insights Into the Selective Phase of Nuclear Pore with a Perfectly Repeated 12mer GLFG Peptide"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
IDPs and Biological Order Across Length Scales
Discussion Leaders: Monica Sharma (Genentech , United States)
5:30 pm - 5:50 pm
Milan Hazra (Weizmann Institute of Science, Israel)
"Electrostatics Dictates Dynamics and Structure of Biomolecular Condensates"
5:50 pm - 6:00 pm
Discussion
6:00 pm - 6:20 pm
Mina Farag (Washington University in St. Louis, United States)
"Condensates of Disordered Proteins Have Small-World Network Structures and Interfaces Defined by Expanded Conformations"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
David Moses (University of California, Merced, United States)
"Adaptive Structure in Disordered Proteins in the Test Tube and in the Cell"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
Mireia Seuma (Institute for Bioengineering of Catalonia (IBEC), Spain)
"Using Deep Mutational Scanning to Map Amyloid Nucleation"
7:20 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
IDPs Across the Tree of Life
Discussion Leaders: Steven Boeynaems (Stanford University, United States) and Gabriella Gerlach (CMU-Pitt Program in Computational Biology, University of Pittsburgh, United States)
9:00 am - 9:20 am
Jacqueline Pelham (Rensselaer Polytechnic Institute, United States)
"The FREQUENCY Isoforms of Neurospora crassa Play a Dynamic Role in Clock Regulation"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Bhargy Sharma (Nanyang Technological University, Singapore)
"Intrinsically Disordered Proteins and their Interactions in Slime Fibers Produced by Velvet Worms"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Xiaohan Li (MRC Laboratory of Molecular Biology, United Kingdom)
"A Conserved Stress Tolerance Mechanism for a Tardigrade Disordered Protein"
10:20 am - 10:30 am
Discussion
10:30 am - 10:50 am
Filip Mihalic (Uppsala University, Sweden)
"A Pan-Viral Atlas of Linear Motif-based Interactions with their Human Targets"
10:50 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: The Roadmap From Idea to Technology
Discussion Leader: Alex Holehouse (Washington University School of Medicine, United States)
1:30 pm - 2:30 pm
Panel Discussion
Careers
Virginia Burger (New Equilibrium Biosciences, United States)
Lucia Strader (Duke University, United States)
D. Allan Drummond (The University of Chicago, United States)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes