| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and check-in |
| 4:00 pm - 6:00 pm | Welcome Reception |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Cyclic nucleotide regulated channels |
| 7.30 pm - 7.40 pm | Discussion Leader: Sharona Gordon (Washington) |
| 7:40 pm - 8:05 pm | Gary Yellen (Harvard)
"Inactivation gating and sensor-gate coupling in HCN channels" |
| 8:15 pm - 8:40 pm | Steve Siegelbaum (Columbia)
"Gating of CNG and HCN channels by cyclic nucleotides" |
| 8:50 pm - 9:15 pm | Joao Cabral (Yale)
"Cyclic-nucleotide binding domains of bacterial channels" |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am | Conference Photo |
| 9:00 am - 12:30 pm | Ligand-gated ion channels |
| 9.00 pm - 9.10 pm | Discussion Leader: Cynthia Czajkowski (Wisconsin) |
| 9:15 am - 9:40 am | Steve Sine (Mayo)
"The nicotinic receptor ligand binding domain: structure, conformational changes and coupling to the ion channel" |
| 9:55 am - 10:20 am | Neil Harrison (Cornell)
"Flexible loops couple agonist binding to channel opening in GABA-A and glycine receptors" |
| 10:35 am | Coffee Break |
| 11:05 am - 11:30 am | Eric Gouaux (Columbia)
"Relationships between Structure and Function in AMPA
and NMDA Receptors" |
| 11:45 am - 12:10 pm | Lonnie Wollmuth (SUNY Stonybrook)
"Gating Rearrangements in the Glutamate Receptor Ion Channel" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Exotic ion channels |
| Discussion Leader: Alan Finkelstein (AECOM) |
| 7:40 pm - 8:05 pm | Masato Yasui (JHU)
"Aquaporin-6, an intracellular vesicle aquaporin with anion permeability" |
| 8:15 pm - 8:40 pm | Sergey Bezrukov (NIH)
"Non-selective' channels: Bacterial porins" |
| 8:50 pm - 9:15 pm | Steve Goldstein (Yale)
"K2P potassium channels" |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Voltage dependent gating |
| 9.00 pm - 9.10 pm | Discussion Leader: Clay Armstrong (Penn) |
| 9:15 am - 9:40 am | Dianne Papazian (UCLA)
"Voltage sensor conformational changes and interaction with the pore in potassium channels" |
| 9:55 am - 10:20 am | Dick Horn (Jefferson Med Coll)
"Functional tests of structural models of gating" |
| 10:35 am | Coffee Break |
| 11:05 am - 11:30 am | Pancho Bezannilla (UCLA)
"Gating charge and conformational changes of the voltage sensor" |
| 11:45 am - 12:10 pm | Kenton Swartz (NIH)
"Toxins interacting with the voltage-sensors in Kv channels" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Modulation |
| 7.30 pm - 7.40 pm | Discussion Leader: Jian Yang (Columbia) |
| 7:40 pm - 8:05 pm | Toshi Hoshi (Penn)
"Modification of BK channel gating by oxidation and heme" |
| 8:15 pm - 8:40 pm | Fran Ashcroft (Oxford)
"Metabolic regulation of KATP channels in health and disease" |
| 8:50 pm - 9:15 pm | Bill Catterall (UW Seattle)
"Modulation of Sodium and Calcium Channels by Signaling Complexes" |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Cell biology |
| 9.00 pm - 9.10 pm | Discussion Leader: Carol Deutch (Penn) |
| 9:15 am - 9:40 am | Blanche Schwappach (Heidelberg)
"R-based signals in the trafficking of ion channels - KATP and beyond" |
| 9:55 am - 10:20 am | Min Li (JHU)
"Signals and machinery for forward trafficking" |
| 10:35 am | Coffee Break |
| 11:05 am - 11:30 am | Ed Ziff
"Protein Interactions and the Assembly and Trafficking of AMPA Receptors" |
| 11:45 am - 12:10 pm | Lilly Jan (UCSF)
"Trafficking potassium channels" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Chloride channels & transporters |
| 7.30 pm - 7.40 pm | Discussion Leader: Michael Pusch (Genova) |
| 7:40 pm - 8:05 pm | Criss Hartzell (Emory)
"Bestrophins: a new family of chloride channels" |
| 8:15 pm - 8:40 pm | Lou DeFelice (Vanderbilt)
"Channel Properties of Transporters: ligand binding, kinetics and stoichiometry" |
| 8:50 pm - 9:15 pm | Chris Miller (Brandeis)
"The bacterial CLC: It's not a chloride channel" |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Sensational channels |
| 9.00 pm - 9.10 pm | Discussion Leader: David Corey (Harvard) |
| 9:15 am - 9:40 am | Diana Bautista (UCSF)
"From Peppers to Peppermints: An Emerging Molecular Logic of Thermosensation" |
| 9:55 am - 10:20 am | Scott Ramsey (Harvard)
"TRP channels" |
| 10:35 am | Coffee Break |
| 11:05 am - 11:30 am | Miriam Goodman (Stanford)
"DEG/ENaC channels that detect force in C. elegans touch receptor neurons" |
| 11:45 am - 12:10 pm | Dennis Dougherty (Cal Tech)
"Experiment and Simulation in Studies of Mechanosensitive Channels" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Putting it all together |
| 7.30 pm - 7.40 pm | Discussion Leader: Dan Johnston (Baylor) |
| 7:40 pm - 8:05 pm | Peter Jonas (Freiburg)
"How Kv channels shape action potentials in somata and presynaptic terminals" |
| 8:15 pm - 8:40 pm | John Adelman (Vollum OHSU)
"Roles for SK channels in CA1 neurons" |
| 8:50 pm - 9:15 pm | Jim Surmeir (Northwestern)
"Coordinated GPCR-mediated modulation of ion channels regulates
synaptic integration and neuron firing patterns" |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |
