Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Evolution
Discussion Leader: Giovanna Felis (University of Verona, Italy, Italy)
7:40 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:20 pm
Rodolphe Barrangou (NC State University, United States)
"Applications of CRISPR-Based Technologies to Manipulate Lactic Acid Bacteria"
8:20 pm - 8:35 pm
Discussion
8:35 pm - 9:05 pm
Paul O'Toole (School of Microbiology & APC, Univ. College Cork, Ireland, Ireland)
"Identification of Host Interaction Genes in Lactobacilli"
9:05 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Metabolism
Discussion Leader: Sybille Tachon (Laboratoire de Chimie Bactérienne, France)
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
Michiel Kleerebezem (Wageningen University, The Netherlands)
"To Grow or not to Grow? Lifestyle and Metabolism of Lactococci during Cheese Manufacturing"
9:35 am - 9:50 am
Discussion
9:50 am - 10:05 am
Mark Heggen (University of Wisconsin at Madison, United States)
"(p)ppGpp Promotes Gut Fitness of Limosilactobacillus Reuteri by Enhancing Resistance to an Antimicrobial Secondary Metabolite"
10:05 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:10 am
Herwig Bachmann (VU University, The Netherlands)
"Optimizing Metabolic Activity for Bioconversions with Lactic Acid Bacteria: From Resource Allocation to the Purification of Plant Proteins"
11:10 am - 11:25 am
Discussion
11:25 am - 11:40 am
Anthony Shiver (Stanford University, United States)
"A Mutant Fitness Compendium in Bifidobacterium Breve Reveals Molecular Determinants of Colonization and Host-Microbe Interactions"
11:40 am - 11:50 am
Discussion
11:50 am - 12:00 pm
General Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizer: Sarah Lebeer (University of Antwerp, Belgium)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Bacteriophages
Discussion Leader: Jan Peter van Pijkeren (University of Wisconsin-Madison, United States)
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
Sylvain Moineau (Université Laval, Canada)
"The Arms Race between Streptococcus Thermophilus and its Phages"
8:05 pm - 8:20 pm
Discussion
8:20 pm - 8:35 pm
Shelby Andersen (University of Colorado - Anschutz Medical Campus, United States)
"Serine Recombinase Linked to a Type IV Restriction Enzyme Identifies Diverse Antiphage Defense Systems in Lactic Acid Bacteria"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 9:10 pm
Breck Duerkop (University of Colorado - Anschutz Medical Campus, United States)
"Bacteriophage-host interactions shape bacterial fitness and evolution"
9:10 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Cell Surface
Discussion Leader: Robert Scheffler (Carnegie Institution for Science, United States)
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
Marie-Pierre Chapot-Chartier (INRAE (National Research Institute for Agriculture, Food and the Environment), France)
"Assembly of Rhamnose-Rich Cell Wall Polysaccharides in Lactococci"
9:35 am - 9:50 am
Discussion
9:50 am - 10:05 am
Karina Gabriela Gutierrez Garcia (Carnegie Institution for Science, United States)
"A Genomic Island of a Lactiplantibacillus Plantarum Strain Confers Drosophila-Gut Colonization Specificity"
10:05 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:10 am
Oscar Kuipers (University of Groningen, The Netherlands)
"A New Wave of Antimicrobials: Mimicking Non-Ribosomally Produced Antibiotics by Ribosomal Synthesis and Extensive Posttranslational Modification"
11:10 am - 11:25 am
Discussion
11:25 am - 11:40 am
Graciela Lorca (University of Florida, United States)
"Lactobacillus Johnsonii Extracellular Vesicles as Therapeutic Effectors: Biogenesis, Host Internalization and Mechanistic Targets"
11:40 am - 11:50 am
Discussion
11:50 am - 12:15 pm
Kimberly Kline (University of Geneva, Switzerland)
"Pathogenesis of Enterococcal Polymicrobial Wound Infection"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Vaginal Symbioses
Discussion Leader: Katy Patras (Baylor College of Medicine, United States)
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
Sarah Lebeer (University of Antwerp, Belgium)
"The Isala Project on the Vaginal Microbiome: Lessons Learnt so far on the Key Role of Lactobacilli"
8:05 pm - 8:20 pm
Discussion
8:20 pm - 8:35 pm
Lindsey Burcham (University of Tennessee, United States)
"Contribution of GBS Manganese Homeostasis and the Oxidative Stress Response in Vaginal Persistence"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 9:10 pm
Jacques Ravel (University of Maryland School of Medicine, United States)
"Insights into In Vivo Functions of Vaginal Microbiomes"
9:10 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Food Ecosystems
Discussion Leader: Bob Hutkins (University of Nebraska, United States)
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
Michael Gänzle (University of Alberta, Canada)
"Lactic Acid Bacteria in Traditional and Novel Food Fermentations: Can we Translate Traditional, Indigenous Knowledge Systems to Scientific Knowledge Systems?"
9:35 am - 9:50 am
Discussion
9:50 am - 10:05 am
Vincent Somerville (Université Laval, Canada)
"Extensive Phage and Host Evolution in Cheese Starter Cultures Over an Entire Alp Season"
10:05 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:10 am
Benjamin Wolfe (Tufts University, United States)
"What Controls the Assembly of Fermented Food Microbial Communities?"
11:10 am - 11:25 am
Discussion
11:25 am - 11:40 am
Daniel Garrido (PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE, Chile)
"Emergent Roles of Infant Gut Microbes during Utilization of Human Milk Oligosaccharides Revealed by a Species Deletion Approach"
11:40 am - 11:50 am
Discussion
11:50 am - 12:15 pm
Paul Cotter (Teagasc, Ireland)
"'MASTER'ing the LAB in Fermented Foods"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Biotherapeutics
Discussion Leader: Sara Di Rienzi (Baylor College of Medicine, United States)
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
Yvonne Kapila (UCLA, United States)
"Harnessing the Power of the Oral Microbiome to Address Oral Diseases"
8:05 pm - 8:20 pm
Discussion
8:20 pm - 8:35 pm
Meilin Zhu (MIT, United States)
"Unsaturated fatty acids differentially modulate growth of vaginal Lactobacillus species"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 9:10 pm
Christine Beeton (Baylor College of Medicine, United States)
"Bioengineered Probiotics for the Oral Delivery of Peptide Drugs for the Treatment of Systemic Diseases"
9:10 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Intestinal Symbioses
Discussion Leader: Anthony Shiver (Stanford University, United States)
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
Vanessa Leone (University of Wisconsin-Madison, United States)
"Interactions between Diet and Lactobacillus Community Members on Diurnal Dynamics of Host Innate Immune Outputs"
9:35 am - 9:50 am
Discussion
9:50 am - 10:05 am
Sara Di Rienzi (Baylor College of Medicine, United States)
"Microbial Stimulation of Oxytocin Release from the Intestinal Epithelium Via Secretin Signaling"
10:05 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:10 am
Satya Dandekar (University of California Davis, United States)
"Lactobacillus Drives Repair of the Intestinal Barrier during HIV Infection"
11:10 am - 11:25 am
Discussion
11:25 am - 11:40 am
Wenke Feng (Tulane University , United States)
"Mechanisms of Lacticaseibacillus Rhamnosus GG and the Metabolites in the Prevention/Treatment of Alcohol-Associated Liver Disease"
11:40 am - 11:50 am
Discussion
11:50 am - 12:15 pm
Mindy Engevik (Medical University of South Carolina, United States)
"Characterizing Lactic Acid Bacteria in Early Life Development"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Synthetic Biology
Discussion Leader: William Ludington (Carnegie Institution of Washington, United States)
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
Nik Nair (Tufts University, United States)
"Using Peptides to Study and Engineer Mixed Microbial Systems"
8:05 pm - 8:20 pm
Discussion
8:20 pm - 8:35 pm
Elsa Fristot (Centre de biologie structurale, France)
"New Genetic Toolbox for Lactic Acid Bacteria Engineering : A Part Toolbox Applied for Cancer Therapy"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 9:15 pm
Siliang Li (Rice University, United States)
"Programming Electronic Communication in Lactic Acid Bacteria with Synthetic Biology"
9:15 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure