Saturday |
1:30 pm - 4:30 pm | Arrival and Check-in |
3:00 pm - 3:15 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:15 pm - 4:00 pm | Keynote Session: Where Do You Belong? |
| Discussion Leader: Crina Nimigean (Weill Cornell Medical College, USA) |
3:15 pm - 3:20 pm | Introduction by Discussion Leader |
3:20 pm - 3:50 pm | Poul Nissen (Aarhus University, Denmark) "How Do Primary and Secondary Transporters Switch Side?" |
3:50 pm - 4:00 pm | Discussion |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | Glutamate Receptors |
| Discussion Leaders: Marina Diskowski (Goethe University Frankfurt, Germany) and Manuel Arcangeletti (International School for Advanced Studies (SISSA), Italy) |
5:30 pm - 5:50 pm | Joel Meyerson (Brandeis University, USA) "Structural Mechanism of Glutamate Receptor Activation and Desensitization" |
5:50 pm - 6:00 pm | Discussion |
6:00 pm - 6:20 pm | Jelena Baranovic (NeuroCure, Charité Universitätsmedizin, Germany) "Dynamics of the AMPA Receptor Ligand Binding Domain Layer" |
6:20 pm - 6:30 pm | Discussion |
| Elucidating the Mechanism of Membrane Transporters |
6:30 pm - 6:45 pm | M. Gregor Madej (University of California, Los Angeles, USA) "The pK-Switch Mechanism in MFS Sugar/H+ Symporters" |
6:45 pm - 6:50 pm | Discussion |
6:50 pm - 7:05 pm | Ryan Henderson (University of Groningen, The Netherlands) "Proton Coupling by the Maltose Transporter of Saccharomyces cerevisiae" |
7:05 pm - 7:10 pm | Discussion |
7:10 pm - 7:25 pm | Salome Veshaguri (University of Copenhagen, Denmark) "A Novel Method to Study Transport at the Single Molecule Level: New Insights on Transporter Function and Regulation" |
7:25 pm - 7:30 pm | Discussion |
8:00 pm | Dinner |
Sunday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | Flipping and Gating |
| Discussion Leaders: Jennifer Booker (Birkbeck University of London, United Kingdom) and Andres Jara-Oseguera (National Institute of Neurological Disorders and Stroke, NIH, USA) |
9:00 am - 9:20 am | Camilo Perez (ETH Zürich, Switzerland) "Structure and Mechanism of an ATP-Driven Lipid-Linked Oligosaccharide Flippase" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Oliver Clarke (Columbia University, USA) "Structural Insights into RyR1 Activation" |
9:50 am - 10:00 am | Discussion |
| Gating and Activation of the TRPV1 and CorA Ion Channel |
10:00 am - 10:15 am | Claudio Anselmi (National Heart, Lung, and Blood Institute, NIH, USA) "Mechanism of Activation of the TRPV1 Channel by a Double-Knot Tarantula Toxin" |
10:15 am - 10:20 am | Discussion |
10:20 am - 10:35 am | Fan Yang (University of California, Davis, USA) "Structural Mechanism Underlying Capsaicin Binding and Activation of the TRPV1 Ion Channel" |
10:35 am - 10:40 am | Discussion |
10:40 am - 10:55 am | Doreen Matthies (National Cancer Institute, NIH, USA) "Single-Particle Cryo-EM Studies of a 200 kDa Magnesium Ion Channel Reveal Large Structural Changes Upon Gating" |
10:55 am - 11:00 am | Discussion |
11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:30 pm | Mentorship Component: Career Panel |
| Discussion Leader: Cristina Paulino (University of Zurich, Switzerland) |
1:30 pm - 2:15 pm | Panel Discussion |
| "Which Career Path Do You Choose?" |
|
- Rebecca Kirk (Nature Publishing Group, United Kingdom)
- Poul Nissen (Aarhus University, Denmark)
- Shin Numao (Novartis Pharma AG, Switzerland)
|
2:15 pm - 2:30 pm | General Discussion |
2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
3:00 pm | Seminar Concludes |