Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm
Keynote Session: Going with the Flow: From Dashing X-rays to Sluggish Electrons
Discussion Leader: Makayla Freitas (Oregon Health Science University, United States)
3:15 pm - 3:20 pm
Opening Remarks
3:20 pm - 3:50 pm
Hartmut Luecke (UC Irvine, United States)
"Helicobacter pylori : The Evil Duo of a pH-Gated Urea Channel and a Cytoplasmic Urease"
3:50 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Protein-Membrane Interactions
Discussion Leader: Qin Yu (IMBB, ETH Zürich, Switzerland)
5:30 pm - 5:50 pm
Thibaud Dieudonné (Aarhus University, Denmark)
"Structural Basis of ATP8B1/CDC50A Regulation Revealed by CryoEM"
5:50 pm - 5:55 pm
Discussion
5:55 pm - 6:15 pm
Katarzyna Drozdzyk (University of Zurich, Switzerland)
"Cryo-EM Structures of CALHM Channels of the Human Placenta"
6:15 pm - 6:20 pm
Discussion
6:20 pm - 6:40 pm
Kamil Nosol (ETH Zürich, Switzerland)
"Structural and Functional Comparison of the Multidrug Transporter ABCB1 and the Phosphatidylcholine Translocator ABCB4"
6:40 pm - 6:45 pm
Discussion
6:45 pm - 7:05 pm
Whitney Stevens-Sostre (University of Wisconsin-Madison, United States)
"A Hydrophobic Nexus at the PAS-cap/Globular PAS/CNBhD Interface Tunes Deactivation Kinetics of hERG Channels"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
Anastasiia Sukalskaia (University of Zurich, Switzerland)
"Cryo-EM Structures of the TTYH Family Reveal a Novel Architecture for Lipid Interactions"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Molecular Mechanisms of Channels and Receptors
Discussion Leader: Prashant Rao (OHSU, United States)
9:00 am - 9:20 am
Gonzalo Cebrero (University of Basel, Switzerland)
"Structure Elucidation by Fiducial-Assisted Cryo-EM: Two Successful Cases"
9:20 am - 9:25 am
Discussion
9:25 am - 9:45 am
Yvonne Hellmich (Goethe University Frankfurt, Germany)
"Structural and Functional Investigation of the Novel Ectoine Uptake System EctI"
9:45 am - 9:50 am
Discussion
9:50 am - 10:10 am
Elizabeth Kim (Weill Cornell Medicine, United States)
"Identification of HCN1 Allosteric Sites for Small Molecule Modulation"
10:10 am - 10:15 am
Discussion
10:15 am - 10:35 am
Mark Loebel (University of Oxford, United Kingdom)
"Structural Basis for Cystine Transport and Regulation Across the Lysosomal Membrane"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Laura Piot ( Institut de Biologie de l'Ecole Normale Supérieure (IBENS), France)
"New Insights on the Structure, Function and Pharmacology of Delta Receptors (GluD)"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Advice
Discussion Leader: Charlott Stock (Aarhus University, Denmark)
1:30 pm - 2:25 pm
Panel Discussion
Career Advice
Herbert Nar (Boehringer Ingelheim GmbH & Co. KG, Germany)
Lesley Anson (Anson Scientific, United Kingdom)
Hartmut Luecke (UC Irvine, United States)
2:25 pm - 2:30 pm
Closing Remarks
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
