| Saturday |
| 2:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Keynote Session: Tribbles-1: A Novel Locus Regulating Lipid Metabolism Identified from Human Genetics |
| Discussion Leaders: John Melchior (University of Cincinnati, USA) and Eser Zerenturk (Baker IDI Heart and Diabetes Institute, Australia) |
| 3:45 pm - 4:15 pm | Robert Bauer (University of Pennsylvania, USA)
"Tribbles-1: A Novel Locus Regulating Lipid Metabolism Identified from Human Genetics" |
| 4:15 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Lipoprotein Composition and Function |
| Discussion Leaders: Caitlin Murdoch (Duke University Medical Center, USA) and Allison Andraski (Harvard T.H. Chan School of Public Health, USA) |
| 7:30 pm - 7:45 pm | Allyson Morton (Harvard T.H. Chan School of Public Health, USA)
"ApoE and ApoC-III Interact to Modulate the Metabolism of HDL ApoA-I in Humans" |
| 7:45 pm - 7:50 pm | Discussion |
| 7:50 pm - 8:05 pm | Amy Burke (University of Western Ontario, Canada)
"Naringenin Supplementation of a Low Fat Diet Enhances the Reversal of Metabolic Dysfunction, Promotes Atherosclerosis Regression and Improves Lesion Pathology in Ldlr-/- Mice" |
| 8:05 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:25 pm | Rebecca Holme (Medical College of Wisconsin, USA)
"Modification of HDL by Reactive Aldehydes Impairs HDL's Athero-Protective Functions" |
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:45 pm | Monika Sharma (University of Otago, New Zealand)
"Calcium Dependent Endocytosis and Recycling of Lipoprotein(a) in HepG2 Cells" |
| 8:45 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:05 pm | John Melchior (University of Cincinnati, USA)
"Apolipoprotein A-II Impacts the Lipoproteome, Structure and Function of Apolipoprotein A-I Containing Lipoproteins" |
| 9:05 pm - 9:10 pm | Discussion |
| 9:10 pm - 9:25 pm | James Thierer (Carnegie Institution for Science / Johns Hopkins University, USA)
"The Larval Zebrafish as a Model for Beta-Lipoprotein Biology and Unbiased Drug Discovery" |
| 9:25 pm - 9:30 pm | Discussion |
| Sunday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Genetic Regulation of Lipoprotein Metabolism and
Atherosclerosis |
| Discussion Leaders: Lars Elmann Larsen (AMC Medical Research, The Netherlands) and Robert Bauer (University of Pennsylvania, USA) |
| 9:00 am - 9:20 am | Xin Bi (University of Pennsylvania, USA)
"C6orf106 Is a Novel Regulator of Lipoprotein Metabolism" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Cassandra Hayne (University of North Carolina at Chapel Hill, USA)
"Biochemical Analysis of the LPL Truncation Variant, LPLS447X" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Liye Zhou (SUNY Downstate Medical Center, USA)
"MiR-1200 Differentially Modulates Plasma LDL and HDL-Cholesterol Levels to Reduce Hyperlipidemia and Atherosclerosis in Mice" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am - 10:50 am | Eser Zerenturk (Baker IDI Heart and Diabetes Institute, Australia)
"Identification of Novel Regulators of Cholesterol Metabolism with Therapeutic Potential for Cardiovascular Disease" |
| 10:50 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Mentorship Component: Career Panel |
| Discussion Leaders: Scott Gordon (National Heart, Lung, and Blood Institute, NIH, USA) and Marjolein van den Boogert (Academic Medical Center, The Netherlands) |
| 1:30 pm - 2:30 pm | Panel Discussion |
| "A Successful Career in Academic Research" |
|
- Frank Sacks (Harvard T.H. Chan School of Public Health, USA)
- Kasey Vickers (Vanderbilt University Medical Center, USA)
|
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
| 3:00 pm | Seminar Concludes |
