Exploring, Understanding and Controlling Nanoscale Structure and Dynamics in Liquid

Liquid phase electron microscopy (LPEM) refers to a class of methods for imaging specimens in liquid with nanometer spatial resolution using electron microscopy. LPEM overcomes the key limitation of electron microscopy: since the electron optics requires a high vacuum, the sample must be stable in a vacuum environment. However, many types of specimens relevant to biology, materials science, chemistry, geology, and physics, change their properties when placed in a vacuum. This Gordon Research Conference aims discussing the latest research results, advances in method, and future directions of LPEM. It presents an international forum for scientists from multiple disciplines and at different stages in their career. Discussion will focus on the usage and development of this new in situ technology to study fundamental aspects involving the structure and dynamics of organic and inorganic materials, and biological specimens. Topics will include: innovation in liquid cells and holder designs; microscopy and spectroscopy; beam sample interactions and the use of low dose LPEM; nucleation and growth of nanoparticles and crystals; electrochemistry; imaging in ionic liquids; the self-assembly and structure of soft matter; studying biological samples, for example, protein function; and advanced image acquisition, analysis and data interpretation. Both theoretical and experimental approaches are welcome.