| SUNDAY | 
| 2:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) | 
| 6:00 pm | Dinner | 
| 7:30 pm - 7:45 pm | Welcome / Introductory Comments by GRC Site Staff | 
| 7:45 pm - 9:30 pm | EVOLUTIONARY VIEW OF THE LUNG | 
|  | Discussion Leader: Lynn Schnapp (University of Washington) | 
| 7:45 pm - 8:20 pm | David Warburton (Children’s Hospital, USC "Lung progenitor functions in integrated development and rebuilding of the lung"
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| 8:20 pm - 8:35 pm | Discussion | 
| 8:35 pm - 9:15 pm | Ross Metzger (USCF) "Branching Subroutines in Lung Development and Evolution"
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| 9:15 pm - 9:30 pm | Discussion | 
| MONDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am - 12:30 pm | BUILDING BLOCKS OF THE LUNG | 
|  | Discussion Leader: Anne Pearl (University of Cincinnati) | 
| 9:00 am - 9:30 am | David Ornitz (Washington University) "Growth factors in Lung Development"
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| 9:30 am - 9:45 am | Discussion | 
| 9:45 am - 9:55 am | Gianni  Carraro (University of Giessen) "Critical role of miR-142 on the regulation of FGF signaling in the lung"
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| 9:55 am - 10:05 am | Discussion | 
| 10:05 am - 10:40 am | Group Photo / Coffee Break | 
| 10:40 am - 11:00 am | Nan Tang  (UCSF) "Control of mitotic spindle angle by RAS-regulated ERK1/2 signaling determines airway shape"
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| 11:00 am - 11:10 am | Discussion | 
| 11:10 am - 11:30 pm | Adam Giangreco (Imperial College) "Beta catenin regulates normal and preinvasive airway epithelial growth and lineage choice via modulation of stem cell adhesiveness"
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| 11:30 pm - 11:40 pm | Discussion | 
| 11:45 am - 12:15 pm | Akiko Hata (Tufts University) "MicroRNA regulation of pulmonary vascular smooth muscle proliferation and differentiation"
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| 12:15 pm - 12:30 pm | Discussion | 
| 12:30 pm | Lunch | 
| 1:30 pm - 4:00 pm | Free Time | 
| 4:00 pm - 6:00 pm | Poster Session: Lung Development | 
| 6:00 pm | Dinner | 
| 7:30 pm - 9:30 pm | BALANCING ACT: REPAIR PATHWAYS GONE AWRY | 
|  | Discussion Leader: Tom Mariani (University of Rochester) | 
| 7:30 pm - 8:00 pm | Martin Privalsky (University of California, Davis) "Transcriptional co-repressors in development and COPD"
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| 8:00 pm - 8:10 pm | Discussion | 
| 8:10 pm - 8:40 pm | Paul Noble (Duke University) "Role of Hyaluronan in Lung injury and repair"
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| 8:40 pm - 8:55 pm | Discussion | 
| 8:55 pm - 9:20 pm | Enid Neptune (Johns Hopkins University) "Molecular mechanisms of genetic emphysema"
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| 9:20 pm - 9:30 pm | Discussion | 
| TUESDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am - 12:30 pm | DESTROYING THE LUNG | 
|  | Discussion Leader: William Parks (University of Washington) | 
| 9:00 am - 9:30 am | Dean Sheppard (UCSF) "New Roles of Integrins in Lung Injury and Repair"
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| 9:30 am - 9:45 am | Discussion | 
| 9:45 am - 9:55 am | Megan Ballinger (University of Michigan) "The Role Of An Important Negative Regulator Of Toll Like Receptor Signaling, IRAK-M, In Mediating The Generation Of Antioxidants During Hyperoxic Lung Injury"
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| 9:55 am - 10:05 am | Discussion | 
| 10:05 am - 10:35 | Coffee Break | 
| 10:35 am - 11:10 am | Tyler Jacks (MIT) "Injury and Lung Cancer"
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| 11:10 am - 11:30 am | Discussion | 
| 11:30 am - 12:10 pm | Irina Petrache (Indiana University) "Contribution of endothelial apoptosis in lung pathology/emphysema"
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| 12:10 pm - 12:30 pm | Discussion | 
| 12:30 pm | Lunch | 
| 1:30 pm - 4:00 pm | Free Time | 
| 4:00 pm - 6:00 pm | Poster Session: Lung Injury | 
| 6:00 pm | Dinner | 
| 7:30 pm - 9:30 pm | SCARRED FOR LIFE? FIBROSIS AND MATRIX REMODELING | 
|  | Discussion Leader: Rachel Chambers (University College London) | 
| 7:30 pm - 8:00 pm | Christine Garcia  (University of Texas, Southwestern Medical Center) "Telomerase mutations and Idiopathic Pulmonary Fibrosis"
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| 8:00 pm - 8:10 pm | Discussion | 
| 8:10 pm - 8:40 pm | Daniel J. Tschumperlin (Harvard School of Public Health) "Mechanical influences on lung fibroblast behavior"
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| 8:40 pm - 8:55 pm | Discussion | 
| 8:55 pm - 9:20 pm | Andreas Günther (Justus-Liebig University, Germany) "Chronic epithelial injury as trigger event in lung fibrosis"
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| 9:20 pm - 9:30 pm | Discussion | 
| WEDNESDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am - 12:30 pm | SEEING IS BELIEVING: IMAGING THE LUNG | 
|  | Discussion Leader: Sharon Rounds (Brown University) | 
| 9:00 am - 9:30 am | Matthias Ochs (Hannover Medical School) "If seeing is believing, is counting knowing? Morphometry of the lung"
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| 9:30 am - 9:40 am | Discussion | 
| 9:40 am - 9:50 am | Nazgol Seyednejad (UBC) "The Remodeling of the Small Conducting Airways in COPD"
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| 9:50 am - 10:00 am | Discussion | 
| 10:00 am | Coffee Break | 
| 10:30 am - 11:00 am | Matthew (Max) Krummel (UCSF) "In vivo imaging of lymphocyte function in the lung"
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| 11:00 am - 11:15 am | Discussion | 
| 11:15 am - 11:45 am | Phil Low (Purdue University) "Ligand-targeted therapeutic and imaging agents for inflammatory diseases"
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| 11:45 am - 12:00 pm | Discussion | 
| 12:00 pm - 12:20 pm | Li-Chin Yao (UCSF) "Dynamics of button-like junctions in the endothelium of airway lymphatics in development and inflammation"
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| 12:20 pm - 12:30 pm | Discussion | 
| 12:30 pm | Lunch | 
| 1:30 pm - 4:00 pm | Free Time | 
| 4:00 pm - 6:00 pm | Poster Session: Lung Repair | 
| 6:00 pm | Dinner | 
| 7:30 pm - 9:30 pm | THE ROAD TO RECOVERY: PATHWAYS IN LUNG REPAIR | 
|  | Discussion Leader: Barry Stripp (Duke University) | 
| 7:30 pm - 8:00 pm | Oliver Eickelberg (Helmholtz Zentrum München) "New Pathways in Lung repair"
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| 8:00 pm - 8:10 pm | Discussion | 
| 8:10 pm - 8:40 pm | Richard Cummings (Emory University) "Role of Glycans in lung injury: hitting the sweet spot"
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| 8:40 pm - 8:55 pm | Discussion | 
| 8:55 pm - 9:20 pm | Hal Chapman (University of California, San Francisco) "Signaling pathways in epithelial-mesenchymal transition"
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| 9:20 pm - 9:30 pm | Discussion | 
| THURSDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 8:30 am - 9:00 am | Business Meeting | 
|  | Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair | 
| 9:00 am - 12:30 pm | INTERVENTION: REBUILDING THE LUNG | 
|  | Discussion Leader: Melanie  Konigshoff (Helmholtz Zentrum München) | 
| 9:00 am - 9:30 am | Barry Shea (Massachusetts General Hospital) "Leaky lungs: linking acute lung injury and fibrosis"
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| 9:30 am - 9:40 am | Discussion | 
| 9:40 am - 9:50 am | Poornima Mahavadi (Geissen) "Lysosomal stress and apoptosis of alveolar epithelial cells in a murine model of amiodarone induced pulmonary fibrosis"
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| 9:50 am - 10:00 am | Discussion | 
| 10:00 am | Coffee Break | 
| 10:30 am - 11:00 am | Erica Herzog (Yale University) "Tissue-engineered Lungs for in vivo implantation"
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| 11:00 am - 11:15 am | Discussion | 
| 11:15 am - 11:30 pm | Peter Chen (University of Washington) "Syndecan-1 Regulation of Airway Re-epithelialization"
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| 11:30 am - 11:40 am | Discussion | 
| 11:40 am - 11:55 pm | Xinguo  Jiang (Stanford) "Adenovirus-Mediated Hypoxia Inducible Factor (HIF)-1Alpha Gene Transfer Promotes Repair Of Airway Allograft Microvasculature And Attenuates Chronic Rejection"
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| 11:55 am - 12:05 am | Discussion | 
| 12:05 am - 12:20 pm | Sekhar Reddy (University of Illinois, Chicago) "Targeted Deletion Of Jun/Ap-1 In Alveolar Epithelial Cells Causes Progressive Emphysema And Worsens Cigarette Smoke-Induced Lung Inflammation"
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| 12:20 am - 12:30 am | Discussion | 
 
| 12:30 pm | Lunch | 
| 1:30 pm - 4:00 pm | Free Time/Soccer Match! | 
| 4:00 pm - 6:00 pm | Poster Session: Interventions | 
| 6:00 pm | Dinner | 
| 7:30 pm - 9:30 pm | INTERVENTION: FIXING THE LUNG | 
|  | Discussion Leader: Bethany Moore (University of Michigan) | 
| 7:30 pm - 8:10 pm | Renata Pasqualini and Wadih Arap (MD Anderson) "New strategies for targeting the lung vasculature"
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| 8:10 pm - 8:30 pm | Discussion | 
| 8:30 pm - 9:10 pm | Sheila Violette (Stromedix) "Going from bench to bedside in the real world: avb6 antibody and fibrosis"
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| 9:10 pm - 9:30 pm | Discussion | 
| FRIDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am | Departure |