SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | A Foundation for Future Innovations in Lung Biology and Medicine |
| Discussion Leader: Barry Stripp (Cedars-Sinai Medical Center, LA) |
7:40 pm - 8:20 pm | Ed Morrisey (University of Pennsylvania)
"Basic science advances in lung development, injury and repair"
|
8:20 pm - 8:35 pm | Discussion |
8:35 pm - 9:15 pm | Lynn Schnapp (Washington)
"Advances in lung translational research"
|
9:15 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Building the Lung |
| Discussion Leader: Wellington Cardoso (Boston University) |
9:00 am - 9:40 am | Xin Sun (Wisconsin)
"Genetic control of upper airway patterning" |
9:40 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 11:00 am | Parviz Minoo (USC)
"New insights into epithelial-mesenchymal signaling in the developing lung"
|
11:00 am - 11:15 am | Discussion |
11:15 am - 11:30 am | Short Talk: Michael Lafemina (UCSF)
"A role for the lung-specific tight junction protein Claudin-18 in lung injury and alveolarization"
|
11:30 am - 11:45 am | Discussion |
11:45 am - 12:15 pm | David Warburton (CHLA)
"Developmental basis of lung diseases: what happens when the rubber hits the lung"
|
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session: Lung Development and Developmental Disorders |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Developmental Mechanisms in Lung Disease |
| Discussion Leader: Tom Mariani (Rochester) |
7:30 pm - 8:10 pm | Jeff Whitsett (Cincinnati)
"Diseases of aberrant epithelial development"
|
8:10 pm - 8:25 pm | Discussion |
8:25 pm - 8:40 pm | Zea Borok (USC)
|
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Michael O'Reilly (Rochester)
"Environmental modifiers of progenitor cell selection in the developing alveolus"
|
9:15 pm - 9:30 pm | Discussion |
9:30 pm | Evening Social and informal poster viewing |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Epithelial Maintenance, Repair, and Regeneration |
| Discussion Leader: Jason Rock (UCSF) |
9:00 am - 9:40 am | Dan Weiss (Vermont)
"Stem Cells and Cell Therapies in Lung Disease"
|
9:40 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 11:00 am | Hal Chapman (UCSF)
"Novel multipotent progenitors of the alveolar epithelium"
|
11:00 am - 11:15 am | Discussion |
11:15 am - 11:30 am | Short Talk: Susan Reynolds (National Jewish)
"Brush Cells: Welcome to the basal cell lineage?"
|
11:30 am - 11:45 am | Discussion |
11:45 am - 12:15 pm | Scott Randell (UNC)
"miRNA regulation of human airway epithelial progenitor cells"
|
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session: Lung Injury and Disease Mechanisms |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Out of Control - Lung Cancer |
| Discussion Leader: Carla Kim (Harvard) |
7:30 pm - 8:10 pm | A. McGarry Houghton (Fred Hutchinson Cancer Center)
|
8:10 pm - 8:25 pm | Discussion |
8:25 pm - 8:40 pm | Brigitte Gomperts (UCLA)
"Reactive oxygen species in airway stem cell homeostasis and lung carcinogenesis"
|
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Mark Onaitis (Duke)
"Cellular origins and regulation of non-small cell lung cancer"
|
9:15 pm - 9:30 pm | Discussion |
9:30 pm | Evening Social and informal poster viewing |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Scarred for Life? Fibrosis and Matrix Remodeling |
| Discussion Leader: Bethany Moore (Michigan) |
9:00 am - 9:40 am | Naftali Kaminski (Pittsburgh)
"Biomarkers of idiopathic pulmonary fibrosis"
|
9:40 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 10:45 am | Short Talk: Tien Peng (U of Pennsylvania)
"Stromal activation by Wnt signaling defines a cellular niche capable of clonal expansion after fibrotic lung injury"
|
10:45 am - 10:55 am | Discussion |
10:55 am - 11:25 am | Patricia Sime (Rochester)
"PPAR agonists in lung disease" |
11:25 am - 11:45 am | Discussion |
11:45 am - 12:15 pm | Andreas Gunter (Giessen)
"Trigger mechanisms and profibrotic signaling pathways in lung fibrosis"
|
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session: Stem Cells and Regenerative Medicine |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Beyond the Genome - Epigenetics, non-coding RNA's and Lung Disease |
| Discussion Leader: Ed Morrisey (Penn) |
7:30 pm - 8:10 pm | David Schwartz (UC Denver)
"Epigenetic basis for environmental lung disease"
|
8:10 pm - 8:25 pm | Discussion |
8:25 pm - 8:40 pm | Maria Ramirez (Boston University)
"Long non-coding RNA's in lung development and disease"
|
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Avi Spira (Boston University)
"The COPD transcriptome and predisposition to cancer"
|
9:15 pm - 9:30 pm | Discussion |
9:30 pm | Evening Social and informal poster viewing |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am - 9:00 am | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
9:00 am - 12:30 pm | Next Generation Approaches in Imaging and Disease Modeling |
| Discussion Leader: Jahar Bhattacharya (Columbia) |
9:00 am - 9:40 am | Darrell Kotton (Boston University)
"Pluripotent stem cell models of development and disease"
|
9:40 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 11:00 am | Tom Mariani (Rochester) |
11:00 am - 11:15 am | Discussion |
11:15 am - 11:30 am | Short Talk: Michael Litvack (Toronto)
"Stem cell-derived alveolar-type macrophages"
|
11:30 am - 11:45 am | Discussion |
11:45 am - 12:15 pm | Luis Ortiz (Pittsburgh)
"Stromal cell-derived microvesicles as modulators of tissue inflammation and remodeling"
|
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Breaking Down Barriers between Basic and Translational Research,
Academia and Industry
|
| Discussion Leader: Paul Noble (Cedars Sinai Medical Center, LA) |
7:30 pm - 8:10 pm | Ric Boucher (UNC-CH)
"Basic insights into therapies for Cystic Fibrosis"
|
8:10 pm - 8:25 pm | Discussion |
8:25 pm - 8:40 pm | Henry Danahay (Novartis)
"Translating basic advances in academic research to drug discovery"
|
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Jay Kolls (Pittsburgh)
"IL-17 and the development of novel therapies for lung disease"
|
9:15 pm - 9:30 pm | Discussion |
9:30 pm | Evening Social and informal poster viewing |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |