Sunday |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | The State of Lung Science and Opportunities in Respiratory Medicine |
| Discussion Leader: Thomas Mariani (University of Rochester Medical Center, USA) |
7:40 pm - 7:50 pm | Opening Remarks |
7:50 pm - 8:25 pm | Marsha Wills-Karp (Johns Hopkins Bloomberg School of Public Health, USA) "A Brief History of Lung Science" |
8:25 pm - 8:40 pm | Discussion |
8:40 pm - 9:15 pm | Jim Kiley (National Heart, Lung, and Blood Institute, NIH, USA) "Current and Future Opportunities in Respiratory Medicine Research" |
9:15 pm - 9:30 pm | Discussion |
Monday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Early Developmental Mechanisms and Related Disease |
| Discussion Leader: David Ornitz (Washington University in St. Louis, USA) |
9:00 am - 9:35 am | Xin Sun (University of Wisconsin-Madison, USA) "Mesenchymal Coordination of Lung Development" |
9:35 am - 9:50 am | Discussion |
9:50 am - 10:25 am | Edward Morrisey (University of Pennsylvania, USA) "Regulation of Lung Stem Cells and Emergence of Endodermal Lineages" |
10:25 am - 10:40 am | Discussion |
10:40 am - 11:10 am | Coffee Break |
11:10 am - 11:45 am | Larry Nogee (Johns Hopkins University, USA) "The Genetics of Preterm Respiratory Distress" |
11:45 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Christin Kuo (Stanford University, USA) "Formation of a Lung Neurosensory Organ by a Novel Mode of Epithelial Cell Movement" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Gloria Pryhuber (University of Rochester, USA) "Lymphocyte Immaturity and Dysfunction in Preterm Infants" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Perinatal Developmental Mechanisms and Chronic Pediatric Disease |
| Discussion Leader: Susan Guttentag (Vanderbilt University, USA) |
7:30 pm - 8:00 pm | Jeffrey Whitsett (Cincinnati Children's Hospital Medical Center, USA) "LungMAP: A Molecular Atlas for Lung Development" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Johanna Andrae (Uppsala University, Sweden) "PDGF-A in Alveolar Formation: Updating the Paradigm" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Tom Ferkol (Washington University in St. Louis, USA) "Phenotypic and Genetic Heterogeneity in the Ontogeny of Pediatric Lung Disease" |
9:20 pm - 9:30 pm | Discussion |
Tuesday |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Injury from Respiratory Pathogens |
| Discussion Leader: Joseph Mizgerd (Boston University School of Medicine, USA) |
9:00 am - 9:35 am | Susanne Herold (Universities of Giessen and Marburg Lung Center, Germany) "Pneumonia-Associated Immuno-Modulation and Lung Injury" |
9:35 am - 9:50 am | Discussion |
9:50 am - 10:25 am | Albert Osterhaus (University of Veterinary Medicine Hannover, Foundation, Germany) "Pathological Mechanisms and Emerging Respiratory Viruses Infection" |
10:25 am - 10:40 am | Discussion |
10:40 am - 11:10 am | Coffee Break |
11:10 am - 11:45 am | Derek Pociask (University of Pittsburgh, USA) "T Cell Control of Epithelial Repair During Influenza Infection" |
11:45 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Namasivayam Ambalavanan (University of Alabama at Birmingham, USA) "The Airway Microbiome at Birth and Its Relationship to Neonatal Chronic Lung Disease" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Thomas Mariani (University of Rochester Medical Center, USA) "The Healthy Infant Nasal Transcriptome: A Benchmark Study" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Inflammation and Immunity |
| Discussion Leader: Bethany Moore (University of Michigan, USA) |
7:30 pm - 8:00 pm | Pyong Woo Park (Boston Children's Hospital / Harvard Medical School, USA) "Matrix Control of Inflammation" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Anuradha Ray (University of Pittsburgh School of Medicine, USA) "The Role of Dendritic Cells in the Regulation of Immunity vs. Tolerance" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Ragini Vittal (Indiana University School of Medicine, USA) "Complement Activation: An Aide or a Master?" |
9:20 pm - 9:30 pm | Discussion |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Chronic Injury and Progressive Disease |
| Discussion Leader: Andreas Guenther (Universities of Giessen and Marburg Lung Center, Germany) |
9:00 am - 9:35 am | Jeanine D'Armiento (Columbia University, USA) "Evolution of Emphysema: Smokes and Fumes and Regeneration" |
9:35 am - 9:50 am | Discussion |
9:50 am - 10:25 am | Edwin Silverman (Brigham and Women's Hospital, USA) "COPDGene and Redefining Genetics of Lung Disease" |
10:25 am - 10:40 am | Discussion |
10:40 am - 11:10 am | Coffee Break |
11:10 am - 11:45 am | Rama Mallampalli (University of Pittsburgh, USA) "Discovery and Development of Novel Regulators of Lung Inflammation" |
11:45 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Scott Budinger (Northwestern University, USA) "Macrophage Ontogeny Is Critical to the Development of Lung Fibrosis" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Marie-Liesse Asselin-Labat (Walter and Eliza Hall Institute, Australia) "FGFR1 Inhibition in Patient-Derived Xenograft Models of Squamous Cell Carcinoma" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | Cancer and Personalized Medicine |
| Discussion Leader: Tomoko Betsuyaku (Keio University School of Medicine, Japan) |
7:30 pm - 8:00 pm | Avi Spira (Boston University, USA) "Precision Medicine for Detection and Prevention of Lung Cancer" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Erica Jackson (Genentech Inc., USA) "Intra-Tumor Heterogeneity and Personalized Therapeutic Targeting" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Kwok-Kin Wong (Dana Farber Cancer Institute, USA) "The Molecular Basis of Lung Tumorigenesis and Molecular-Driven Therapy" |
9:20 pm - 9:30 pm | Discussion |
Thursday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Injury Resolution and Tissue Repair |
| Discussion Leader: Lynn Schnapp (Medical University of South Carolina, USA) |
9:00 am - 9:35 am | Irina Petrache (National Jewish Health, USA) "Ceramide and Sphingolipids in Homeostasis and Chronic Disease" |
9:35 am - 9:50 am | Discussion |
9:50 am - 10:25 am | Bruce Levy (Brigham and Women's Hospital / Harvard Medical School, USA) "Pro-Resolution Lipid Mediators in Homeostasis and Repair" |
10:25 am - 10:40 am | Discussion |
10:40 am - 11:10 am | Coffee Break |
11:10 am - 11:45 am | Barry Stripp (Cedars Sinai Medical Center, USA) "The Ontogeny of Epithelial Progenitors in Injury Resolution and Repair" |
11:45 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Jin-Ah Park (Harvard T.H. Chan School of Public Health, USA) "Asthmatic Bronchial Epithelial Cell Injury-Repair Responses" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Jonathan McQualter (Cedars-Sinai Medical Center, USA) "Mesenchymal Cell Diversity Controls the Fate of Adult Lung Epithelial Stem Cells" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Therapeutic Tissue Engineering and Regeneration |
| Discussion Leader: Jason Rock (University of California, San Francisco, USA) |
7:30 pm - 8:00 pm | Bernard Thebaud (University of Ottawa, Canada) "Cell-Based Therapeutics for Neonatal Disease" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Andrew Vaughan (University of California, San Francisco, USA) "Progenitor Cell Plasticity During Epithelial Regeneration in Mice and Humans" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Laura Niklason (Yale University, USA) "Approaches to Tissue Regeneration: State of the Field" |
9:20 pm - 9:30 pm | Discussion |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |