Sunday 
 
 
2:00 pm - 9:00 pm 
	
Arrival and Check-in
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 7:40 pm 
	
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
 
 
						
7:40 pm - 9:30 pm 
	
Keynote Session: Post-COVID Opportunities to Broaden Lung Biology 
 
 
 
						
7:40 pm - 8:00 pm 
	
"Progress and Opportunities in Lung Development, Injury and Repair:  A NHLBI Perspective" 
 
 
 
						
8:00 pm - 8:15 pm 
	
Discussion
 
 
						
8:15 pm - 8:55 pm 
	
"Breaking Down Barriers to Lung Repair and Regeneration: Unlocking the Plasticity of Alveolar Epithelial Cells" 
 
 
 
						
8:55 pm - 9:10 pm 
	
Discussion
 
 
						
9:10 pm - 9:30 pm 
	
General Discussion
 
 
						
	Monday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am - 12:30 pm 
	
Post-COVID Priorities in Lung Injury Repair 
 
 
 
						
9:00 am - 9:20 am 
	
"Lung Stem Cells in Injury Repair" 
 
 
 
						
9:20 am - 9:30 am 
	
Discussion
 
 
						
9:30 am - 9:45 am 
	
"Human iPSCs to Study the Molecular Programs of Lung Injury and Repair" 
 
 
 
						
9:45 am - 9:50 am 
	
Discussion
 
 
						
9:50 am - 10:10 am 
	
"Mechanistic Themes from the Marfan Lung" 
 
 
 
						
10:10 am - 10:20 am 
	
Discussion
 
 
						
10:20 am - 10:50 am 
	
Group Photo / Coffee Break
 
 
						
10:50 am - 11:10 am 
	
"Signaling Factors Promoting Pathological Fibroblast Differentiation in Injury Models" 
 
 
 
						
11:10 am - 11:20 am 
	
Discussion
 
 
						
11:20 am - 11:35 am 
	
"BDNF Regulation of Airway Mucins" 
 
 
 
						
11:35 am - 11:40 am 
	
Discussion
 
 
						
11:40 am - 11:55 am 
	
"Non-Resolvable COVID-19: A Tale of Transitional Stem Cell Recruitment and Extracellular Matrix Deposition" 
 
 
 
						
11:55 am - 12:00 pm 
	
Discussion
 
 
						
12:00 pm - 12:20 pm 
	
"Emphysema or Fibrosis: Two Sides of the Same Coin" 
 
 
 
						
12:20 pm - 12:30 pm 
	
Discussion
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						
3:00 pm - 4:00 pm 
	
The GRC Power Hourâ„¢ 
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring. 
 
 
 
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 9:30 pm 
	
Tipping the Balance from Dysplastic to Regenerative Repair 
 
 
 
						
7:30 pm - 7:50 pm 
	
"Fungal Dysbiosis in Post-Influenza MRSA Infection" 
 
 
 
						
7:50 pm - 8:00 pm 
	
Discussion
 
 
						
8:00 pm - 8:15 pm 
	
"Role of IL-10 in transcriptomic alterations in the developing mouse lung caused by in utero electronic-cigarette aerosol exposures" 
 
 
 
						
8:15 pm - 8:20 pm 
	
Discussion
 
 
						
8:20 pm - 8:35 pm 
	
"Function of Genetic Determinants for COPD and IPF in Lung Epithelial Cells" 
 
 
 
						
8:35 pm - 8:40 pm 
	
Discussion
 
 
						
8:40 pm - 8:55 pm 
	
"Role of Diet and Gut Microbiome in Regulating Lung Injury Responses" 
 
 
 
						
8:55 pm - 9:00 pm 
	
Discussion
 
 
						
9:00 pm - 9:20 pm 
	
"Epithelial Determinants of Functional Alveolar Repair" 
 
 
 
						
9:20 pm - 9:30 pm 
	
Discussion
 
 
						
	Tuesday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am - 12:30 pm 
	
 
 
						
9:00 am - 9:20 am 
	
"Transcriptional Control and Evolution of Lung Alveolar Cell Fates" 
 
 
 
						
9:20 am - 9:30 am 
	
Discussion
 
 
						
9:30 am - 9:45 am 
	
"Context-Dependent Requirements for Mitochondria Function in Lung" 
 
 
 
						
9:45 am - 9:50 am 
	
Discussion
 
 
						
9:50 am - 10:10 am 
	
"Age of the Fibroblast: Transition or Existing on a Spectrum?" 
 
 
 
						
10:10 am - 10:20 am 
	
Discussion
 
 
						
10:20 am - 10:50 am 
	
Coffee Break
 
 
						
10:50 am - 11:10 am 
	
"A 4-Dimensional Fabric: Considerations of Space and Time in Lung Development and Disease" 
 
 
 
						
11:10 am - 11:20 am 
	
Discussion
 
 
						
11:20 am - 11:35 am 
	
"Defining the Pulmonary Developmental Niche: Identifying Placental Mechanisms of Developmental Lung Injury" 
 
 
 
						
11:35 am - 11:40 am 
	
Discussion
 
 
						
11:40 am - 11:55 am 
	
"Proteomic Analysis of Human Bronchopulmonary Dysplasia Lung" 
 
 
 
						
11:55 am - 12:00 pm 
	
Discussion
 
 
						
12:00 pm - 12:20 pm 
	
"Submucosal Gland and Rare Cell Progenitors in the Ferret Proximal Airway" 
 
 
 
						
12:20 pm - 12:30 pm 
	
Discussion
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 9:30 pm 
	
Insights from Single Cell Resolution 
 
 
 
						
7:30 pm - 7:50 pm 
	
"COVID-19: Insights from In Vitro  Infection and a Human SARS-CoV-2 Challenge Study" 
 
 
 
						
7:50 pm - 8:00 pm 
	
Discussion
 
 
						
8:00 pm - 8:15 pm 
	
"Endothelial S1PR1 Suppresses Endothelin 1 Signaling and Attenuates Fibrosis After Influenza Virus Infection" 
 
 
 
						
8:15 pm - 8:20 pm 
	
Discussion
 
 
						
8:20 pm - 8:35 pm 
	
"Effect of Environmental Lighting on Circadian Gating on Lung Injury from Influenza" 
 
 
 
						
8:35 pm - 8:40 pm 
	
Discussion
 
 
						
8:40 pm - 8:55 pm 
	
"Genetic and Epigenetic Regulators of Alveolar Progenitor Function in Regeneration" 
 
 
 
						
8:55 pm - 9:00 pm 
	
Discussion
 
 
						
9:00 pm - 9:20 pm 
	
"Alveolar Responses to Recurrent Injury" 
 
 
 
						
9:20 pm - 9:30 pm 
	
Discussion
 
 
						
	Wednesday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am - 12:30 pm 
	
 
 
						
9:00 am - 9:20 am 
	
"Fibroblast Roles in Fibrosis and Repair" 
 
 
 
						
9:20 am - 9:30 am 
	
Discussion
 
 
						
9:30 am - 9:45 am 
	
"Directed Differentiation of Pluripotent Stem Cells into Functional Lung-Specific Mesenchyme" 
 
 
 
						
9:45 am - 9:50 am 
	
Discussion
 
 
						
9:50 am - 10:10 am 
	
"Fibroblast Tuning of the Inflammatory Niche" 
 
 
 
						
10:10 am - 10:20 am 
	
Discussion
 
 
						
10:20 am - 10:50 am 
	
Coffee Break
 
 
						
10:50 am - 11:10 am 
	
"The Mesenchymal Niche During Airway Epithelial Regeneration" 
 
 
 
						
11:10 am - 11:20 am 
	
Discussion
 
 
						
11:20 am - 11:35 am 
	
"Wnt Signaling in Mesenchymal Vascular Progenitor (MVPC) Drives Adaptive Angiogenesis During Fibrosis and Regulates Pulmonary Tissue Repair" 
 
 
 
						
11:35 am - 11:40 am 
	
Discussion
 
 
						
11:40 am - 11:55 am 
	
"Biomarkers of Pulmonary Fibrosis – Their Utility in Drug Discovery" 
 
 
 
						
11:55 am - 12:00 pm 
	
Discussion
 
 
						
12:00 pm - 12:20 pm 
	
"Unusual Interstitial Pneumonia: How Should We Think About Fibrosis in Children?" 
 
 
 
						
12:20 pm - 12:30 pm 
	
Discussion
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 9:30 pm 
	
The Lung as a Sensory Organ 
 
 
 
						
7:30 pm - 7:50 pm 
	
"Linking Tuft Cells to Airway Damage Sensing and Repair" 
 
 
 
						
7:50 pm - 8:00 pm 
	
Discussion
 
 
						
8:00 pm - 8:15 pm 
	
"Cellular and Molecular Diversity of Peripheral Glia in the Lung and their Development" 
 
 
 
						
8:15 pm - 8:20 pm 
	
Discussion
 
 
						
8:20 pm - 8:35 pm 
	
"Sensory Mechanisms of the Mammalian Airways" 
 
 
 
						
8:35 pm - 8:40 pm 
	
Discussion
 
 
						
8:40 pm - 8:55 pm 
	
"Infection Induced Inflammatory Signal Triggers Lung Dysplastic Remodeling" 
 
 
 
						
8:55 pm - 9:00 pm 
	
Discussion
 
 
						
9:00 pm - 9:20 pm 
	
"Multiple Modes of Lung Repair in Severe Viral Pneumonia" 
 
 
 
						
9:20 pm - 9:30 pm 
	
Discussion
 
 
						
	Thursday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
8:30 am - 9:00 am 
	
Business Meeting 
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s) 
 
 
						
9:00 am - 12:30 pm 
	
Circulating Cells in the Lung-Body Dialogue 
 
 
 
						
9:00 am - 9:20 am 
	
"Molecular Pathology in Patients with SARS-CoV-2 Pneumonia Reveals Disease Pathobiology" 
 
 
 
						
9:20 am - 9:30 am 
	
Discussion
 
 
						
9:30 am - 9:45 am 
	
"TREM2 Regulates the Lung Innate Immune Response and the Severity of Hyperoxia Induced Lung Injury" 
 
 
 
						
9:45 am - 9:50 am 
	
Discussion
 
 
						
9:50 am - 10:10 am 
	
"Macrophage Heterogeneity During Repair of Acute Lung Injury" 
 
 
 
						
10:10 am - 10:20 am 
	
Discussion
 
 
						
10:20 am - 10:50 am 
	
Coffee Break
 
 
						
10:50 am - 11:10 am 
	
"Early Life Pulmonary Viral Infection Alters Long Term Function and Structure" 
 
 
 
						
11:10 am - 11:20 am 
	
Discussion
 
 
						
11:20 am - 11:35 am 
	
"Tissue-Resident Macrophage Regulation of Airway Submucosal Gland Development" 
 
 
 
						
11:35 am - 11:40 am 
	
Discussion
 
 
						
11:40 am - 11:55 am 
	
"Fatty Acid Binding Protein 5 (FABP5) Promotes the Resolution of Inflammation in a Mouse Model of Chronic Obstructive Pulmonary Disease (COPD) Exacerbations" 
 
 
 
						
11:55 am - 12:00 pm 
	
Discussion
 
 
						
12:00 pm - 12:20 pm 
	
"Profiling and Mapping of Hematopoietic Stem Cell Reservoirs in the Human Lung" 
 
 
 
						
12:20 pm - 12:30 pm 
	
Discussion
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 9:30 pm 
	
Keynote Session: The Rules and Exceptions of Pulmonary Vessels 
 
 
 
						
7:30 pm - 7:50 pm 
	
"Pulmonary Vascular Remodeling a Breakdown in Communication?" 
 
 
 
						
7:50 pm - 8:00 pm 
	
Discussion
 
 
						
8:00 pm - 8:15 pm 
	
"SIN3A Directs Lung and Pulmonary Vascular Development by Controlling the Balance of Histone Acetylation" 
 
 
 
						
8:15 pm - 8:20 pm 
	
Discussion
 
 
						
8:20 pm - 8:40 pm 
	
"Beyond Water: A Surprising Role for Aquaporin 1 in Regulating Lung Vascular Cell Function" 
 
 
 
						
8:40 pm - 8:50 pm 
	
Discussion
 
 
						
8:50 pm - 9:20 pm 
	
"Rearranging the Genome for the First Breath at Birth" 
 
 
 
						
9:20 pm - 9:30 pm 
	
Discussion
 
 
						
	Friday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am 
	
Departure