Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: New Frontiers in Pulmonary Health and Disease
Discussion Leader: Susan Guttentag (Vanderbilt University, USA)
3:45 pm - 3:55 pm
Introduction by Discussion Leader
3:55 pm - 4:20 pm
Gisli Jenkins (University of Nottingham, United Kingdom)
"Can Breathing Promote Lung Fibrosis? The Role of Mechanotransduction and Integrins in the Development of Pulmonary Fibrosis"
4:20 pm - 4:25 pm
Discussion
4:25 pm - 4:30 pm
General Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Linking Lung Development, Injury and Repair: Lessons from In Vitro and In Vivo Studies
Discussion Leader: Andreas Guenther (Justus Liebig University Giessen, Germany)
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:50 pm
Leonor Gouveia (Uppsala University, Sweden)
"Lung-Specific Deletion of Pdgfa Leads to Alveolar Development Arrest"
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:10 pm
Veronika Winkelmann (University of Ulm, Germany)
"Barrier Disturbances of the Alveolar-Capillary Barrier"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:30 pm
Yue Ren (University of Rochester Medical Center, USA)
"Regulation of Connective Tissue Type Mast Cells and Their Role in Bronchopulmonary Dysplasia"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:50 pm
Yan (Tina) Zhang (University of California, San Diego, USA)
"E3 Ubiquitin Ligase FBXW7 Controls Airway Cell Fate"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:10 pm
Nathalie Fuentes (Penn State College of Medicine, USA)
"Estrogen Regulation of Inflammatory Mediators and Pulmonary Function in Ozone-Induced Inflammation"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:30 pm
General Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Insights from Basic
Research Paving the Way for New Therapies
Discussion Leader: Kent Pinkerton (University of California, Davis, USA)
9:00 am - 9:20 am
Stephania Cormier (University of Tennessee Health Science Center, USA)
"Exposure of the Developing Lung to Environmental Pollutants and the Development of Asthma"
9:20 am - 9:25 am
Discussion
9:25 am - 9:40 am
Sander van Riet (Leiden University Medical Center, The Netherlands)
"Generation of Alveolar Epithelial Cells and Endothelial Cells from Human Induced Pluripotent Stem Cells"
9:40 am - 9:45 am
Discussion
9:45 am - 10:00 am
Jared Mereness (University of Rochester, USA)
"Type IV Collagen Promotes Pulmonary Epithelial Spreading and Wound-Closure via Integrin 1 and PI3K"
10:00 am - 10:05 am
Discussion
10:05 am - 10:20 am
Jennifer Sucre (Vanderbilt University, USA)
"Hyperoxia Exposure of Developing Lung Epithelium Promotes Activated Wnt Signaling in Underlying Mesenchyme"
10:20 am - 10:25 am
Discussion
10:25 am - 10:40 am
Prajakta Oak (Comprehensive Pneumology Center, Helmholtz Zentrum Muenchen, Germany)
"Monocyte-Centered Inflammatory Responses Driving Pulmonary Injury in Neonatal Chronic Lung Disease"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
Ankita Burman (Vanderbilt University, USA)
"ER Stress Effector C/EBP Homologous Protein (CHOP) Augments AEC Apoptosis and Worsens Lung Fibrosis"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Careers Opportunities with a PhD: Academia, Government and Industry
Discussion Leader: Jason Rock (Boston University School of Medicine, USA)
1:30 pm - 1:40 pm
Introduction by Discussion Leader: An Academic Perspective
1:40 pm - 2:30 pm
Panel Discussion
Careers Opportunities with a Ph.D. - Point of Views of the Industry (Pharma) and the Government (NHLBI)
James Kiley (National Heart, Lung and Blood Institute, NIH, USA)
Paul Levesque (Bristol-Myers Squibb, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes