Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: New Paradigms for Modeling Development, Disease and Aging in the Lung
Discussion Leader: Susan Guttentag (Vanderbilt University, USA)
3:45 pm - 4:10 pm
Jin-Ah Park (Harvard University, USA)
"Mechanical Force, Airway Remodeling and Epithelial Cell Unjamming"
4:10 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
Aaron Weiner (University of Pennsylvania, USA)
"Mesenchyme-Free Expansion and Transplantation of Alveolar Progenitor Cells: A Step Toward Cell-Based Regenerative Therapies"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Keynote Session: Preclinical Models of Developmental Lung Disease / The Role of the Lung Microenvironment in Development and Aging
Discussion Leader: Anne-Karina Perl (Cincinnati Children's Hospital Medical Center, USA)
7:30 pm - 7:55 pm
Anne Hilgendorff (Comprehensive Pneumology Center, Ludwig Maximilian University of Munich / Helmholtz Zentrum München, Germany)
"Translatable Findings Identified by Preclinical Models of Neonatal Lung Disease"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:15 pm
Semil Choksi (University of California, San Francisco, USA)
"Transcriptional Networks Regulating Multiciliogenesis in the Mammalian Airway"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:35 pm
Yan Hu (University of Colorado Denver, USA)
"Identification of Wnt/β-Catenin Responsive Epithelial Progenitor Cells in the Adult Lung"
8:35 pm - 8:40 pm
Discussion
8:40 pm - 8:55 pm
Rhiannon Werder (Center for Regenerative Medicine, Boston University, USA)
"A CRISPRi Approach to Investigate Lung Function Risk Alleles in iPS-Derived Lung Epithelial Cells"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:15 pm
Sarah Wicher (Mayo Clinic, USA)
"Proteostasis and Senescence in the Aging Lung"
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Approaches to Complex Signaling Networks in Lung Development and Lung Injury
Discussion Leader: Melanie Koenigshoff (University of Colorado Denver, USA)
9:00 am - 9:15 am
Aja Aravamudhan (Mayo Clinic, USA)
"Targeting TBK1 to Reduce Fibroblast Activation"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Rita Costa (Comprehensive Pneumology Center, Helmholtz Zentrum München, Germany)
"Drug Repurposing for Wnt/β-Catenin Induced Lung Repair in Chronic Obstructive Pulmonary Disease"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Luisa Morales-Nebreda (Northwestern University, USA)
"Age Determines the Tissue Protective Function of Regulatory T-Cells During Influenza A Virus-Induced Lung Injury"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Prestina Smith (Emory University, USA)
"Effects of Different Routes of Endotoxin Injury on Barrier Function in Alcoholic Lung Syndrome"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Cody Aros (David Geffen School of Medicine at UCLA, USA)
"A Dynamic Wnt-Secreting Niche Regulates Proximal Airway Regeneration"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Colleen Bartman (Mayo Clinic, USA)
"Oxygen Exposure and Circadian Biology in the Premature Developing Airway"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Exploring Career Opportunities in Lung Biology in Academia and Industry
Discussion Leader: Daniel Tschumperlin (Mayo Clinic, USA)
1:30 pm - 2:30 pm
Panel Discussion
Exploring Career Opportunities in Lung Biology in Academia and Industry
Namasivayam Ambalavanan (University of Alabama at Birmingham, USA)
Costanza Casiraghi (Chiesi Farmaceutici SpA, Italy)
Melanie Koenigshoff (University of Colorado Denver, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
