Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: It's All About the Extracellular Environment
Discussion Leader: Alberto Hidalgo (Charité Univeristätsmedizin Berlin, Germany)
3:45 pm - 4:15 pm
Lynn Schnapp (University of Wisconsin School of Medicine and Public Health, United States)
"It's All About the Extracellular Environment!"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Players and Mechanisms of Lung Injury and Regeneration
Discussion Leader: Hirofumi Kiyokawa (Boston University School of Medicine, United States)
7:30 pm - 7:45 pm
Yue (Helen) Zhang (Stanford University/HHMI, United States)
"Autocrine Insulin-like Growth Factor 2 Controls Self-renewal of Pulmonary Neuroendocrine Stem Cells"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Manwai Chan (University of Illinois at Chicago, United States)
"Sphingosine-1-Phosphate Regulate Alveolar Type I Cell Behavior During Repair Of Acute Lung Injury"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Anthea Weng (Northwestern University, United States)
"Alveolar Epithelial Vulnerabilities During Cell Division and Differentiation: Implications for Repair, Regeneration and Fibrosis"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Jessie Huang (Boston University, United States)
"Mechanisms of Alveolar Epithelial Type 2 Cell Self-Renewal in Lung Injury and Repair"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Amber Sogge (Cincinnati Children's Hospital Medical Center , United States)
"Defining Cell-Specific Epithelial Response to Influenza Infection in Lung Alveolar Organoids"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
John Russell (University of Cambridge, United Kingdom)
"Branching Towards Ex Vivo Models to Study Cell Fate and Morphogenesis in the Human Lung"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Linking Disease Mechanisms and Therapies to Promote Pulmonary Health
Discussion Leader: Rene Girard (MD Anderson Cancer Center UT Health Graduate School of Biomedical Sciences, United States)
9:00 am - 9:15 am
Helen Warheit-Niemi (Cincinnati Children's Hospital Medical Center, United States)
"Understanding the Role of Chromatin Remodeling Complex PRC2 in AEP Function and Lung Regeneration Post-viral Pneumonia"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Avery Bogart (Vanderbilt University, United States)
"Elevated Circulating Cell-Free Hemoglobin Drives Endothelial Glycocalyx Destruction and Lung Inflammation in Sepsis"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Sonia Giambelluca (Charité - Universitätsmedizin Berlin, Germany)
"Crystal-mediated Inflammation in Lung Fibrosis"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Preeti Yadav (University of California San Francisco, United States)
"Macrophages Drive Fibroblast Collagen Expression Via Arg1-dependent Ornithine Loading"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Alexia Perryman (University of California, San Diego, United States)
"Pulmonary Endothelial Specific Knockout of Hypoxia Inducible Factors (HIF) Alters Eosinophil Recruitment in Murine Model of Allergic Airway Disease"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Harish Narasimhan (University of Virginia, United States)
"Immune-Epithelial Progenitor Interactions Drive Dysplastic Lung Repair Post Viral Pneumonia"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Paths in Lung Biology
Discussion Leader: Oindrila Paul (Children's Hospital of Philadelphia, United States)
1:30 pm - 2:30 pm
Panel Discussion
The Upside of Academia
Darrell Kotton (Boston University, United States)
Susan Majka (University of Colorado-National Jewish Health, United States)
Andrew Vaughan (University of Pennsylvania, United States)
Ali May (Icahn School of Medicine at Mount Sinai, United States)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes