Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Conceptual Advances in Lymphatic Vessel Biology
Discussion Leader: Kathleen Caron (University of North Carolina at Chapel Hill, United States)
7:40 pm - 8:00 pm
Taija Makinen (Uppsala University, Sweden)
"Principles of Endothelial Resilience in Lymphatic Capillaries"
8:00 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
Late-Breaking Topic
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Jonathan Kipnis (Washington University in St. Louis, United States)
"Meningeal Lymphatics Control Brain Function"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Gou Young Koh (Institute for Basic Science / Korea Advanced Institute of Science and Technology, South Korea)
"Exploring Novel Lymphatics for CSF Outflow or Brain Clearance"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
New Paradigms in Lymphatic Development
Discussion Leaders: Friedemann Kiefer (European Institute for Molecular Imaging, University of Münster, Germany) and Ching-Ling (Ellen) Lien (Children's Hospital Los Angeles / University of Southern California, United States)
9:00 am - 9:20 am
Oliver Stone (University of Oxford, United Kingdom)
"Developmental Origins of Lymphatic Endothelium"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
Short Talk Selected from Poster Abstracts
9:40 am - 9:45 am
Discussion
9:45 am - 10:05 am
Guillermo Oliver (Northwestern University, United States)
"Molecular Characterization of the Functional Roles of Lymphatics Secreted Reelin in Cardiac Growth and Repair"
10:05 am - 10:15 am
Discussion
10:15 am - 10:25 am
Short Talk Selected from Poster Abstracts
10:25 am - 10:30 am
Discussion
10:30 am - 10:55 am
Coffee Break
10:55 am - 11:05 am
Short Talk Selected from Poster Abstracts
11:05 am - 11:10 am
Discussion
11:10 am - 11:30 am
Karina Yaniv (Weizmann Institute of Science, Israel)
"Formations and Malformations of Lymphatic Vessels"
11:30 am - 11:40 am
Discussion
11:40 am - 11:50 am
Short Talk Selected from Poster Abstracts
11:50 am - 11:55 am
Discussion
11:55 am - 12:15 pm
Nathan Lawson (University of Massachusetts Chan Medical School, United States)
"Implementing Conditional Genetics in Zebrafish to Study Lymphatic Development"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizers: Hasina Outtz Reed (Weill Cornell Medicine, United States), Dennis Jones (Boston University Chobanian and Avedisian School of Medicine, United States) and Karina Yaniv (Weizmann Institute of Science, Israel)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Understanding and Targeting Lymphatic Vessels in Disease
Discussion Leaders: Melody Swartz (University of Chicago, United States) and Selen Catania (National Heart, Lung, and Blood Institute, NIH, United States)
7:30 pm - 7:50 pm
Barbara Garmy-Susini (INSERM, France)
"Resolution of Inflammation in Lymphedema, a Novel Therapeutic Pathway for an Unmet Medical Need"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Short Talk Selected from Poster Abstracts
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
Paul Riley (University of Oxford, United Kingdom)
"The Role of the Cardiac Lymphatics During Neonatal Heart Regeneration"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Short Talk Selected from Poster Abstracts
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Susan Quaggin (Northwestern University, United States)
"Mechanosensation and FOXO1: Tied Together in the Lymphatics"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Lymphatic Vessel Drainage, Mechanics and Function
Discussion Leaders: Maike Frye (University Medical Center Hamburg-Eppendorf, Germany) and Michael Davis (University of Missouri, United States)
9:00 am - 9:20 am
Kari Alitalo (University of Helsinki / Wihuri Research Institute, Finland)
"Manipulating VEGF-C and its Signaling Sidekick"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
Short Talk Selected from Poster Abstracts
9:40 am - 9:45 am
Discussion
9:45 am - 10:05 am
Joseph Rutkowski (Texas A&M University School of Medicine, United States)
"Lymphatics and Lymphangiogenesis in Kidney Pathophysiology"
10:05 am - 10:15 am
Discussion
10:15 am - 10:25 am
Short Talk Selected from Poster Abstracts
10:25 am - 10:30 am
Discussion
10:30 am - 10:55 am
Coffee Break
10:55 am - 11:05 am
Short Talk Selected from Poster Abstracts
11:05 am - 11:10 am
Discussion
11:10 am - 11:30 am
Steven Proulx (University of Bern, Switzerland)
"High-Resolution Imaging of Cerebrospinal Fluid Clearance Pathways to Lymphatics"
11:30 am - 11:40 am
Discussion
11:40 am - 11:50 am
Short Talk Selected from Poster Abstracts
11:50 am - 11:55 am
Discussion
11:55 am - 12:15 pm
Jerome Breslin (University of South Florida, United States)
"Obesity, Metabolic Syndrome, and Lymphatic Dysfunction"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
The Lymphatic System, Stem Cells and Metabolism
Discussion Leaders: Xiaolei Liu (Temple University, United States) and Jorge Castorena (Tulane University, United States)
7:30 pm - 7:50 pm
Shiri Gur-Cohen (School of Medicine, University of California San Diego, United States)
"Beyond Boundaries: Lymphatic Vascular Niches Expand Stem Cell Potency"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Short Talk Selected from Poster Abstracts
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
Late-Breaking Topic
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Short Talk Selected from Poster Abstracts
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Anne Eichmann (Yale School of Medicine, United States)
"Organ-Specific Lymphatic Development"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Emerging Insights on Lymphatics in Vascular and Cardiovascular Disease
Discussion Leaders: Young Hong (University of Southern California, United States) and Stefan Schulte-Merker (Westfälische Universität Münster, Germany)
9:00 am - 9:20 am
Pia Ostergaard (St George's, University of London, United Kingdom)
"Deep Phenotyping in Primary Lymphatic Anomalies"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
Short Talk Selected from Poster Abstracts
9:40 am - 9:45 am
Discussion
9:45 am - 10:05 am
Late-Breaking Topic
10:05 am - 10:10 am
Discussion
10:10 am - 10:20 am
Short Talk Selected from Poster Abstracts
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:15 am
Mariona Graupera (Josep Carreras Leukaemia Research Institute, Spain)
"Insights on PI3K Mutations in Lymphatic Malformations"
11:15 am - 11:25 am
Discussion
11:25 am - 11:35 am
Short Talk Selected from Poster Abstracts
11:35 am - 11:40 am
Discussion
11:40 am - 12:00 pm
Miikka Vikkula (Institute de Duve / UCLouvain, Belgium)
"Primary Lymphedema: Expanding the Complex Genetic Background and Pathophysiological Pathways"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:15 pm
Short Talk Selected from Poster Abstracts
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Lymphatics in Cancer and Metastasis
Discussion Leaders: Michael Detmar (ETH Zurich, Switzerland) and Shan Liao (University of Calgary, Canada)
7:30 pm - 7:50 pm
Late-Breaking Topic
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:15 pm
Dennis Jones (Boston University Chobanian and Avedisian School of Medicine, United States)
"Extracellular Matrix and Regulation of Anti-Tumor Immunity"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:30 pm
Short Talk Selected from Poster Abstracts
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
Timothy Padera (Mass General Hospital, Harvard Medical School, United States)
"Transcriptional Changes in Lymphatic Muscle Cells with Age"
8:55 pm - 9:05 pm
Discussion
9:05 pm - 9:25 pm
Late-Breaking Topic
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Immunomodulatory and Hematopoietic Lymphatic Vessels
Discussion Leaders: Brandon Dixon (Georgia Institute of Technology, United States) and Kaska Koltowska (Uppsala University, Sweden)
9:00 am - 9:20 am
Cornelia Halin Winter (ETH Zurich, Switzerland)
"New Insights into the Regulation of Lymphatic CCL21 Gradients"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
Short Talk Selected from Poster Abstracts
9:40 am - 9:45 am
Discussion
9:45 am - 10:05 am
Gwendalyn Randolph (Washington University in St. Louis, United States)
"Dynamic Tracking of Interstitial and Lymphatic Outflow Using Endogenous and Exogenous Tracers"
10:05 am - 10:10 am
Discussion
10:10 am - 10:20 am
Short Talk Selected from Poster Abstracts
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:15 am
Natasha Harvey (University of South Australia, Australia)
"Defining the Mechanisms by which PROX1 Represses Haematopoiesis in the Lymphatic Vasculature"
11:15 am - 11:25 am
Discussion
11:25 am - 11:35 am
Short Talk Selected from Poster Abstracts
11:35 am - 11:40 am
Discussion
11:40 am - 12:00 pm
Late-Breaking Topic
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:25 pm
Late-Breaking Topic
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Lymphatic Vessel Diversity and Heterogeneity in Health and Disease
Discussion Leader: Mark Kahn (University of Pennsylvania, United States)
7:30 pm - 7:40 pm
Short Talk Selected from Poster Abstracts
7:40 pm - 7:45 pm
Discussion
7:45 pm - 8:05 pm
Anjali Kussumbe (University of Oxford, United Kingdom)
"Lymphatics and Lymphangiocrine Signaling in Bones"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
Late-Breaking Topic
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:45 pm
Short Talk Selected from Poster Abstracts
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:10 pm
Late-Breaking Topic
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Short Talk Selected from Poster Abstracts
9:25 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure
