| Saturday |
| 2:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Keynote Session: Exploring the Lymphatics, Follow the Guide! |
| Opening lecture by an expert internationally recognized in the Lymphatics field for his core accomplishments. |
| Discussion Leader: Amelie Sabine (University of Lausanne, Switzerland) |
| 3:45 pm - 4:15 pm | Dontscho Kerjaschki (Medical University of Vienna, Austria)
"Lymphangiogenesis and Renal Transplant Tolerance" |
| 4:15 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Targeting Lymphatic Function for Potential Therapies |
| Discussion Leaders: Joshua Scallan (University of South Florida, USA) and Maike Frye (Uppsala University, Sweden) |
| 7:30 pm - 7:45 pm | Maximilian Nitschke (University of California, San Francisco, USA)
"Cause
and Consequences of Chylothorax Formation in a Mouse Model of Adipocyte-Specific VEGF-C Overexpression" |
| 7:45 pm - 7:50 pm | Discussion |
| 7:50 pm - 8:05 pm | Timothy Norman (Boston University School of Medicine, USA)
"Origin
and Maturation of Pulmonary Lymphatic Endothelial Cells" |
| 8:05 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:25 pm | Samia Bachmann (ETH Zurich, Switzerland)
"In Vivo Regulation of Lymphatic Vessel Function by the Autonomic Nervous System" |
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:45 pm | Scott Zawieja (University of Missouri, USA)
"The
Ca2+-Activated Cl- Channel TMEM16A (ANO1) Modulates Stretch Sensitive Chronotropy in Mouse Collecting Lymphatic Vessels" |
| 8:45 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:05 pm | Samira Jamalian (Imperial College London, United Kingdom)
"Lymphatic Suction Pressure in Collecting Lymphatic Vessels" |
| 9:05 pm - 9:10 pm | Discussion |
| 9:10 pm - 9:25 pm | Li-Hao Huang (Washington University School of Medicine in St. Louis, USA)
"Novel Approaches to Study High-Density Lipoprotein Transport from Tissues" |
| 9:25 pm - 9:30 pm | Discussion |
| Sunday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | New Lymphatic Regulators in Mouse and Fish |
| Discussion Leaders: Kaska Koltowska (Institute for Molecular Bioscience, University of Queensland, Australia) and Jeremiah Bernier-Latmani (University of Lausanne, Switzerland) |
| 9:00 am - 9:15 am | Yvonne Padberg (Institute for Cardiovascular Organogenesis and Regeneration, University of Münster, Germany)
"Novel
and Essential Gene Functions that Govern Lymphatic Formation in Zebrafish and Mice" |
| 9:15 am - 9:20 am | Discussion |
| 9:20 am - 9:35 am | Ajit Muley (Columbia University, USA)
"Notch
and MMPs: Functional Partners in Guiding Lymphatic Development?" |
| 9:35 am - 9:40 am | Discussion |
| 9:40 am - 9:55 am | Enyuan Cao (Monash University, Australia)
"Targeting
Intestinal Lymphatic Lymphocytes: A Potential Route to Treat Immune-Metabolic Diseases" |
| 9:55 am - 10:00 am | Discussion |
| 10:00 am - 10:15 am | Hung Bui (University of Pennsylvania, USA)
"Proteolytic Activation by ADAMTS3 Defines Distinct Mechanisms of Lymphangiogenesis Mediated by VEGFC and VEGFD" |
| 10:15 am - 10:20 am | Discussion |
| 10:20 am - 10:35 am | Sebastien Gauvrit (Max Planck Institute for Heart and Lung Research, Germany)
"A New Role for the Transcription Factor Hhex During Lymphangiogenesis in Zebrafish
and Mouse" |
| 10:35 am - 10:40 am | Discussion |
| 10:40 am - 10:55 am | Xiaolei Liu (Northwestern University, USA)
"Rasip1
in Lymphatic Morphogenesis" |
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Lymphatics in Pathologies |
| Discussion Leaders: Ying Yang (University of South Florida, USA) and Aleksanteri Aspelund (University of Helsinki / Wihuri Research Institute, Finland) |
| 1:30 pm - 1:45 pm | Mirela Berisa (Icahn School of Medicine at Mount Sinai, USA)
"Lymphatic Endothelium Exerts Antioxidant Activity and Protects Breast Cancer Cells from Apoptosis" |
| 1:45 pm - 1:50 pm | Discussion |
| 1:50 pm - 2:05 pm | Chi Nguyen (University of Vienna, Austria)
"12(S)-HETE
and Lymph Node Metastasis: Its Generation in MDA-MB231 Breast Cancer Cells
and Its Signaling in Lymphendothelial Cells" |
| 2:05 pm - 2:10 pm | Discussion |
| 2:10 pm - 2:25 pm | Antoine Louveau (University of Virginia, USA)
"Role of
the Meningeal Lymphatic Vasculature in the Development and Maintenance of Experimental Autoimmune Encephalomyelitis" |
| 2:25 pm - 2:30 pm | Discussion |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
| 3:00 pm | Seminar Concludes |
