Saturday
1:30 pm - 4:30 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm
Keynote Session: Expanding Frontiers of Lymphatic Research
Discussion Leader: Sinem Karaman (Wihuri Research Institute / University of Helsinki, Finland)
3:15 pm - 3:50 pm
Taija Makinen (Uppsala University, Sweden)
"Organ-Specific Origins, Regulation and Functions of the Lymphatic Vasculature"
3:50 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Origin and Formation of Lymphatic Vessels
Discussion Leaders: Kaska Koltowska (Uppsala University, Sweden) and Janette Kazenwadel (University of South Australia, Australia)
5:30 pm - 5:45 pm
Shing Hu (Cornell University, USA)
"The Left-Right Transcription Factor Pitx2 Regulates Intestinal Lymphatic Development"
5:45 pm - 5:50 pm
Discussion
5:50 pm - 6:05 pm
Erin Lucas (University of Colorado Anschutz Medical Campus, USA)
"PD-L1 Regulates Lymph Node Lymphatic Endothelial Cell Division During an Acute Immune Response"
6:05 pm - 6:10 pm
Discussion
6:10 pm - 6:25 pm
Kerstin Wilhelm (Max Planck Institute for Heart and Lung Research, Germany)
"FOXOs Coordinate Cell Cycle Behavior and Differentiation of Lymphatic Endothelial Cells"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:45 pm
Eleftheria Michalaki (Stanford University, USA)
"Spatiotemporally Varying Wall Shear Stress Modulates Lymphatic Endothelial Cell Alignment and Transcriptional Regulation"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:05 pm
Shann Yu (University of Chicago, USA)
"Sterile Dermal Lymphangiogenesis Promotes ILC2-Mediated Type-2 Immune Responses"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
Simone Laupheimer (Institute of Medical Biology (IMB), A*STAR, Singapore)
"Loss-of-Function Mutations in Carboxypeptidase D Cause a New Syndrome with Lymphedema and Sensorineural Hearing Loss"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Lymphatic Vessel Function in Health and Disease
Discussion Leaders: Rene Haegerling (St. George's, University of London, United Kingdom) and Elizabeth Haining (University of Birmingham, United Kingdom)
9:00 am - 9:15 am
William Repicci (Lymphatic Education & Research Network, USA)
"The Lymphatic Researcher as Advocate in an International Movement"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Claire Trincot (University of North Carolina at Chapel Hill, USA)
"Adrenomedullin Induces Cardiac Lymphangiogenesis After Myocardial Infarction and Regulates Cardiac Edema via Cx43"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Joshua Hooks (Georgia Institute of Technology, USA)
"Characterization and Implementation of a Novel Synthetic Hydrogel Lymphatic"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Ines Martinez-Corral (Uppsala University, Sweden)
"New Insights into Mechanisms Underlying PIK3CA-Driven Vascular Malformations"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Jorge Arasa Aparici (ETH Zurich, Switzerland)
"Transcriptional Profiling of Afferent Lymphatic Capillaries and Collectors Reveals a New Entry Site for Dendritic Cell Migration to Lymph Nodes in Inflammation"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Kim Pin Yeo (National University of Singapore, Singapore)
"Dysfunctional Aortic Lymphatic Vessel in Experimental Atherosclerosis"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
New Trends and Tools in Lymphatic Research
Discussion Leaders: Ruben Fernandez-Rodriguez (Icahn School of Medicine at Mount Sinai, USA) and Paul "Li-Hao" Huang (Washington University in St. Louis School of Medicine, USA)
1:30 pm - 1:45 pm
Gracia Gracia (Monash Institute of Pharmaceutical Sciences, Monash University, Australia)
"High Density Lipoprotein as a Novel Lymph-Directing Platform for Immunotherapies Delivery"
1:45 pm - 1:50 pm
Discussion
1:50 pm - 2:05 pm
Kevin Campbell (University of California, Davis, USA)
"Alginate Systems for Potential Therapeutic Lymphangiogenic Applications"
2:05 pm - 2:10 pm
Discussion
2:10 pm - 2:25 pm
Witold Kilarski (University of Chicago, USA)
"Study of the Migratory Phase of Filaria Infection as an Example Application of Tissue Whole-Mount Imaging Techniques"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes