SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Diabetes and Metabolism |
| Discussion Leader: Mara Duncan (University of Michigan, Ann Arbor, MI, USA) |
7:40 pm - 8:00 pm | Tim McGraw (Cornell Medical School, New York, NY, USA)
"Insulin Regulation of Membrane Trafficking"
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8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:30 pm | Jeffrey Pessin (Albert Einstein College of Medicine, New York, NY, USA)
"Lysosome Regulation in Oxidative and Glycolytic Skeletal Muscle"
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8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:00 pm | Silvia Corvera (University of Massachusetts, Worcester, MA, USA)
"Diabetes and Trafficking: New Areas of Focus"
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9:00 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Zemin Yao (University of Ottawa, Ottawa, Canada)
"Lipid Droplet-Associated Small GTPases Accelerate Triglyceride Turnover in Lipid-Laden Liver Cells Treated with n-3 Fatty Acids" |
9:25 pm - 9:30 pm | Discussion |
9:30 pm - 12:00 am | Refreshments, Posters and Discussion at Snack Bar |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Endocytic Mechanisms at the Plasma Membrane and Endosomes |
| Discussion Leaders: Mary Munson (University of Massachusetts, Worcester, MA, USA) and Satdip Kaur (University of Warwick, Coventry, UK) |
9:00 am - 9:20 am | Sandra Schmid (University of Texas Southwestern Medical Center, Dallas, TX, USA)
"Regulation of Clathrin-Mediated Endocytosis"
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9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Maribel Geli (Institut de Biologia Molecular de Barcelona, Barcelona, Spain)
"Cross-Talk Between PI(4,5)P2 and CK2 Modulates Actin Polymerization During Endocytic Uptake"
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9:50 am - 10:00 am | Discussion |
10:00 am - 10:15 am | Marko Kaksonen (EMBL, Heidelberg, Germany)
"Visualizing the Dynamic Architecture of the Endocytic Machinery"
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10:15 am - 10:25 am | Discussion |
10:25 am | Coffee Break |
10:55 am - 11:15 am | Liz Conibear (University of British Columbia, Vancouver, Canada)
"Large-Scale Identification of Regulatory Interactions in the Yeast Endocytic Pathway"
|
11:15 am - 11:25 am | Discussion |
11:25 am - 11:40 am | Adam Frost (University of Utah, Salt Lake City, UT, USA)
"Near-Atomic Resolution Structure of an ESCRT-III Membrane Remodeling Assembly Determined by 3D Electron Cryo-Microscopy" |
11:40 am - 11:50 am | Discussion |
11:50 am - 12:10 pm | David Owen (CIMR, Cambridge, UK)
"Trafficking and Regulation of VAMP7"
|
12:10 pm - 12:20 pm | Discussion |
12:20 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Host-Pathogen Interactions |
7:30 pm - 7:40 pm | Discussion Leader: Mark Marsh (MRC - UK) |
7:40 pm - 8:00 pm | Marcia Goldberg (MGH, Harvard Medical School)
"Shigella Manipulation of Endocytic Pathway"
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8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:30 pm | Felix Randow (LMB, Cambridge, UK)
"Autophagy in Host-Pathogen Interactions
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8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:00 pm | Janet Iwasa (University of Utah, Salt Lake City, UT, USA)
"Animating Molecular Mechanisms"
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9:00 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Florence Niedergang (Institute Cochin, Paris, France)
"Impaired Phagolysosome Maturation in HIV-I Infected Macrophages and Development of Opportunistic Bacteria" |
9:25 pm - 9:30 pm | Discussion |
9:30 pm - 12:00 am | Refreshments, Posters and Discussion at Snack Bar |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Signaling: Endocytic Trafficking in Cancer and Cellular Physiology |
| Discussion Leaders: Christopher Burd (Yale University, New Haven, CT, USA) and Linton Traub (University of Pittsburgh, PA, USA) |
9:00 am - 9:20 am | Alexander Sorkin (University of Pittsburgh, PA, USA)
"EGF Receptor Endocytosis: Mechanisms and Role in Signaling"
|
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Johanna Ivaska (Turku Centre for Biotechnology, Turku, Finland)
"Integrin and RTK Trafficking Pathways in Cancer"
|
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Mark Von Zastrow (UCSF, San Francisco, CA, USA)
"GPCR Signaling Along the Endocytic Pathway"
|
10:20 am - 10:30 am | Discussion |
10:30 am | Coffee Break |
11:00 am - 11:20 am | JoAnn Trejo (University of California at San Diego, La Jolla, CA, USA)
"A Novel Role for Ubiquitin in GPCR Signaling"
|
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Robbie Loewith (University of Geneva, Geneva, Switzerland)
"The Intimate Relationship Between Sphingolipids and TORC2 in Yeast"
|
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:15 pm | Aimee Edinger (University of California at Irvine, Irvine, CA, USA)
"Starving Cancer Cells to Death with Sphingolipids that Limit Nutrient Access and Autophagy" |
12:15 pm - 12:25 pm | Discussion |
12:25 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Endocytic Regulation in Neurons |
| Discussion Leaders: Victor Faundez (Emory University, Atlanta, GA, USA) and Phyllis Hanson (Washington University, St. Louis, MO, USA) |
7:30 pm - 7:50 pm | Tim Ryan (Cornell Medical School, New York, NY, USA)
"The Cost of Doing Business: The Metabolic Burden of the Synaptic Vesicle Cycle"
|
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Pietro De Camilli (Yale University, New Haven, CT, USA)
"Regulatory Mechanisms in the Last Stages of Clathrin-Mediated Endocytosis"
|
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Rejji Kuruvilla (Johns Hopkins University, Baltimore, MD, USA)
"Endocytic Trafficking and Signaling of Neurotrophins in Neural Development"
|
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Avital Rodal (Brandeis University, Waltham, MA, USA)
"Endosomal Traffic in the Drosophila Immune and Nervous Systems"
|
9:20 pm - 9:30 pm | Discussion |
9:30 pm - 12:00 am | Refreshments, Posters and Discussion at Snack Bar |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Autophagy, Endosomes and Lysosomes |
| Discussion Leader: Santiago Di Pietro (Colorado State, Fort Collins, CO, USA) and Graça Raposo (Institut Curie, Paris, France) |
9:00 am - 9:20 am | Jim Hurley (University of California, Berkeley, CA, USA)
"How Vps4 Recycles ESCRT-III" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Lois Weisman (University of Michigan, Ann Arbor, MI, USA)
"Dynamic Regulation of the Signaling Lipid Phosphatidylinositol 3.5-Bisphosphate"
|
9:50 am - 10:00 am | Discussion |
10:00 am - 10:15 am | Christian Ungermann (University of Osnabrueck, Osnabrueck, Germany)
"A Novel Role of the Rab7 GTPase Ypt7 in Signaling and Membrane Dynamics at the Vacuole" |
10:15 am - 10:25 am | Discussion |
10:25 am | Coffee Break |
10:55 am - 11:15 am | Scott Emr (Cornell University, Ithaca, NY, USA)
"Keeping Your Lysosomes Sparkling Clean: Lysosomal Membrane Protein Turnover"
|
11:15 am - 11:25 am | Discussion |
11:25 am - 11:45 am | Jonathan Weissman (UCSF, San Francisco, CA, USA)
"High Density Genetic Interaction Maps Reveal the Routes of Toxin Entry" |
11:45 am - 11:55 am | Discussion |
11:55 am - 12:15 pm | Anjon Audhya (University of Wisconsin-Madison, Madison, WI, USA)
"Spiraling Toward the Mechanism of Vps32/CHMP4 Polymer Assembly"
|
12:15 pm - 12:25 pm | Discussion |
12:25 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | Breaking Developments / New Directions |
| Discussion Leader: Frances Brodsky (University of California, San Francisco, CA, USA) and Roberto Weigert (National Institutes of Health, Bethesda, MD, USA) |
7:30 pm - 7:45 pm | Alex Ritter (University of Cambridge and NIH)
"Reciprocal Regulation of Cortical Actin and Lytic Granule Secretion in Cytotoxic T Cells"
|
7:45 pm - 7:50 pm | Discussion |
7:50 pm - 8:05 pm | Megan Dennis (Children's Hospital of Philadelphia / University of Pennsylvania, Philadelphia, PA, USA)
"Tubule-Dependent Transport into and out of Melanosomes" |
8:05 pm - 8:10 pm | Discussion |
8:10 pm - 8:25 pm | Rob Piper (University of Iowa, Iowa City, IA, USA)
"A Developmentally Regulated Family of Yeast Tetraspanin-Like Proteins Promotes MVB Sorting" |
8:25 pm - 8:30 pm | Discussion |
8:30 pm - 8:45 pm | Natalie Porat-Shliom (National Institutes of Health, Bethesda, MD, USA)
"Linking Cellular Bioenergetics and Membrane Trafficking In Vivo" |
8:45 pm - 8:50 pm | Discussion |
8:50 pm - 9:05 pm | Anne Kenworthy (Vanderbilt University School of Medicine, Nashville, TN, USA)
"Microtubule Motors Drive Membrane Tubulation in Clathrin-Independent Endocytosis" |
9:05 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Steve Caplan (University of Nebraska Medical Center, Omaha, NE, USA)
"C-Terminal EHD Proteins and Mechanisms Controlling the Biogenesis and Vesiculation of Tubular Recycling Endosomes" |
9:25 pm - 9:30 pm | Discussion |
9:30 pm - 12:00 am | Refreshments, Posters and Discussion at Snack Bar |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Lessons from Evolutionary Conservation |
| Discussion Leaders: Mickey Marks (University of Pennsylvania, Philadelphia, PA, USA) and Sandra Lemmon (University of Miami, Miami, FL, USA) |
9:00 am - 9:20 am | Mark Field (Cambridge University, Cambridge, UK)
"Evolution of Clathrin-Mediated Endocytosis: Insights from Trypanosomes"
|
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Maria Carolina Touz (University of Buenos Aires, Buenos Aires, Argentina)
"The Early-Diverging Protist Giardia lamblia Possesses a Monomeric Adaptor Protein with Dual Epsin-Like Function"
|
9:50 am - 10:00 am | Discussion |
10:00 am - 10:15 am | Kyle Cunningham (Johns Hopkins University, Baltimore, MD, USA)
"Programmed Rupture of the Lysosomal Membrane, from Mammals to Yeast" |
10:15 am - 10:25 am | Discussion |
10:25 am | Coffee Break |
10:55 am - 11:15 am | Jenny Hirst (Cambridge University, Cambridge, UK)
"Where Do Adaptor Proteins Come From?"
|
11:15 am - 11:25 am | Discussion |
11:25 am - 11:45 am | Maya Schuldiner (Weizmann Institute, Rehovot, Israel)
"A VaCuoLAr/Mitochondrial Patch (vCLAMP) in Yeast Mediates Communication Between the Two Organelles"
|
11:45 am - 11:55 am | Discussion |
11:55 am - 12:15 pm | Gia Voeltz (University of Colorado, Boulder, CO, USA)
"New Roles for the ER at Endosome Contact Sites"
|
12:15 pm - 12:25 pm | Discussion |
12:25 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Keynote Session |
7:30 pm - 7:45 pm | Discussion Leader: Beverly Wendland (Johns Hopkins University, Baltimore, MD, USA)
"Introduction and History" |
7:45 pm - 8:45 pm | Tom Kirchhausen (Harvard University, Boston, MA, USA)
"Dynamics of Endocytosis"
|
8:45 pm - 9:10 pm | Discussion |
9:10 pm - 9:30 pm | General Discussion and Closing Remarks |
9:30 pm - 12:00 am | Refreshments, Posters and Discussion at Snack Bar |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |