| SATURDAY |
| 2:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Keynote Lecture |
| 3:45 pm - 4:15 pm | Michael Marks (University of Pennsylvania)
"Molecular mechanisms underlying sorting and organelle maturation in the endolysosomal system" |
| 4:15 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Advances in Endosomal and Lysosomal Biology |
| Discussion Leaders: Sergio Grinstein (University of Toronto, Canada) and William Lamanna (University of California, San Diego)
|
| 7:30 pm - 7:50 pm | Sabrina Jabs (Max Delbruck Center for Molecular Medicine, Germany)
"Proton-Driven Lysosomal Chloride-Accumulation is required for Lysosomal Function" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Braden Lobingier (University of Washington)
"SNARE and SNARE Complex Binding by the SM Protein Vps33 and the HOPS Complex" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:50 pm | Christine Becker (Massachusetts General Hospital/Harvard Medical School)
"Rab39a links caspase-1 activation to phagosome acidification and cellular defense" |
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Emma Martinez (UMC Utrecht, the Netherlands)
"AP-3 and rabip4 coordinately regulate spatial distribution of lysosomes" |
| 9:20 pm - 9:30 pm | Discussion |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Mechanisms of Endocytosis |
| Discussion Leaders: Sandra Schmid (University of Texas Southwestern Medical Center) and Cheryl Chia (University of Melbourne, Australia)
|
| 9:00 am - 9:20 am | Hongying Shen (Yale University)
"Lipid metabolism and the dynamics of endophilin, a N-BAR protein" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Lymarie Maldonado-Baez (National Institutes of Health - NHLBI)
"Hook1 and Rab22 Mediate the Endosomal Sorting of CIE Cargo Proteins into Recycling Tubules" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Steve Jean (University of California, San Diego)
"Coordination of PI(3)P and Rab21 in membrane trafficking" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am - 10:50 am | Natsuko Jin (University of Michigan)
"Modulation of the TORC1 pathway via the signaling lipid phosphatidylinositol 3,5 bis phosphate" |
| 10:50 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Managing career transitions: the dos and don'ts of advancing in an academic job |
| Discussion Leader: Brenda Watt (University of Pennsylvania) |
| Speakers: Sergio Grinstein (University of Toronto, Canada), Michael Marks (University of Pennsylvania), Sandra Schmid (University of Texas Southwestern Medical Center), Beverly Wendland (Johns Hopkins University) |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
| 3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |
