| SATURDAY |
| 1:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Keynote Session |
| Discussion Leaders: Beverly Wendland (John Hopkins University, Baltimore, USA) and Lena Wartosch (Cambridge Institute for Medical Research, Cambridge, UK) |
| 3:45 pm - 4:15 pm | Frances Brodsky (University of California, San Francisco, CA, USA) |
| 4:15 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Endocytic and Trafficking Mechanisms |
| Discussion Leaders: Mara Duncan (University of Michigan, Ann Arbor, MI, USA) and Matthew Gallon (University of Bristol, UK) |
| 7:30 pm - 7:45 pm | Amanda Sadacca (University College London, UK)
"Mapping CHC22 Clathrin Function in the GLUT4 Pathway"
|
| 7:45 pm - 7:50 pm | Discussion |
| 7:50 pm - 8:05 pm | Matteo Giani (University of Twente, Netherlands)
"Simulating the Self-Assembly of Clathrin Cages"
|
| 8:05 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:25 pm | David Busch (University of Texas at Austin, Austin, USA)
"Probing the Role of Steric Pressure in Determining the Shape and Content of Clathrin-Coated Vesicles"
|
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:45 pm | Emily Messelaar (Brandeis University, Massachusetts, USA)
"SH3-Dependent Intramolecular Inhibition of Higher-Order Assembly Regulates F-BAR-Mediated Membrane Deformation"
|
| 8:45 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:05 pm | Luana Sasso (University of Nottingham, UK)
"In Vitro Uptake Studies of Cell Targeting Agents and Nanoparticles"
|
| 9:05 pm - 9:10 pm | Discussion |
| 9:10 pm - 9:25 pm | Mojca Mattiazzi Usaj (University of Toronto, Canada)
"Exploring the Endocytic Pathway by Combining High-Throughput Genetics and High-Content Microscopy"
|
| 9:25 pm - 9:30 pm | Discussion |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 10:00 am | Sorting Pathways in the Endolysosomal System |
| Discussion Leaders: Derek Prosser (John Hopkins University, Baltimore, USA) and Ariana Mullin (Emory University, Atlanta, USA) |
| 9:00 am - 9:15 am | Katherine Varandas (University of California, San Francisco, CA, USA)
"Elucidating Selective Transport Through the Endosomal Retromer Complex"
|
| 9:15 am - 9:20 am | Discussion |
| 9:20 am - 9:35 am | James Reinecke (University of Nebraska Medical Center, Omaha, Nebraska, USA)
"Novel Functions for the Endocytic Recycling Proteins MICAL-L1 and EHD1 in Mitosis"
|
| 9:35 am - 9:40 am | Discussion |
| 9:40 am - 9:55 am | Michael Dores (University of California, San Francisco, CA, USA)
"Regulation of the ALIX Lysosomal Sorting Pathway"
|
| 9:55 am - 10:00 am | Discussion |
| 10:00 am - 11:00 am | Building your Career |
| Discussion Leader: Colin Ratcliffe (McGill University, Canada) |
| Speakers:
- Beverly Wendland (John Hopkins University, Baltimore, USA)
- Roberto Weigert (National Institutes of Health, Bethesda, USA)
- Mara Duncan (University of Michigan, Ann Arbor, MI, USA)
- Frances Brodsky (University of California, San Francisco, CA, USA)
|
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Endocytosis and Lysosomes in Physiology and Disease |
| Discussion Leaders: Frances Brodsky (University of California, San Francisco, CA, USA) and Yui Jin (University of Michigan, Ann Arbor, MI, USA) |
| 1:30 pm - 1:45 pm | Shiuan Wang (Baylor College of Medicine, Houston, USA)
"The Retromer Complex is Required for Rhodopsin Recycling and Its Loss Leads to Photoreceptor Degeneration"
|
| 1:45 pm - 1:50 pm | Discussion |
| 1:50 pm - 2:05 pm | Ralf Leonhardt (Yale University, New Haven, CT, USA)
"Critical Residues in the PMEL N-Terminus Direct the Hierarchical Assembly of Melanosomal Fibrils"
|
| 2:05 pm - 2:10 pm | Discussion |
| 2:10 pm - 2:25 pm | Samantha Dykes (LSU Health Shreveport, USA)
"Peripheral Lysosome Positioning is Dictated by NHE1 and Zeb1 Expression and is Necessary for EMT-Mediated Protease Secretion and Tumor Invasion"
|
| 2:25 pm - 2:30 pm | Discussion |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
| 3:00 pm | Seminar Concludes |
