| ENDOCYTOSIS AT THE SYNAPSE |
| Discussion Leader: Regis Kelly |
| John Heuser (Wash U., St. Louis) |
Landmarks of endocytic processing in the cell: EM structure and localization |
| Pietro DeCamilli (Yale, CT) |
Mechanisms of synaptic vesicle endocytosis |
| Erik Jorgensen (Utah) |
Genetic analysis of neurotransmission in C. elegans |
| MECHANISMS OF VESICLE FORMATION |
| Discussion Leader: Sandra Schmid |
| Margaret (Scottie) Robinson (Cambridge, UK) |
The role of adaptors and adaptor-related complexes in vesicle formation |
| Tom Kirchhausen (Harvard) |
Molecular interactions in coat formation and protein sorting |
| Joel Ybe (UCSF) |
Clathrin heavy chain structure: the light chain binding domain |
| Ernst ter Haar (Harvard) |
Three dimensional structure determination of clathrin heavy chain |
| Regis Kelly (UCSF, CA) |
Role of AP3 in synaptic vesicle biogenesis |
| Sanja Sever (TSRI, CA) |
Regulation of dynamin GTPase and its role in coated vesicle formation |
| Mark McNiven (Mayo Clinic) |
Participation of dynamin in non-clathrin mediated events |
| ENDOCYTIC TRANSPORT & SORTING |
| Discussion Leader: Colin Hopkins |
| David James (Brisbane, Australia) |
Regulated recycling of GLUT 4 in insulin sensitive cells |
| Ira Mellman (New Haven, CT) |
Endosomes and protein sorting in polarized cells |
| Helmut Kramer (UTSWMC, TX) |
Drosophila mutations affecting lysosomal delivery |
| Markus Maniak (Max-Planck, Germany) |
The role of F-actin and associated proteins in the formation and organization of early and late endocytic vesicles |
| John Armstrong (University of Sussex, UK) |
Endocytosis and regulated vacuole fusion in fission yeast |
| MOLECULAR INTERACTIONS AT THE ENDOSOMAL SURFACE |
| Discussion Leader: Phil Stahl |
| Mike Roth (UTSW) |
Phospholipase D and vesicle formation |
| Marino Zerial (EMBL, Germany) |
GTPases and their effectors in endocytic traffic |
| Christian Ungermann (Dartmouth, NH) |
Studies of SNARE pairs in the vacuole to vacuole fusion reaction |
| Crislyn D'Souza Schorey (St. Louis, MO) |
The ARF6 GTPase: Modulating membrane transport and cytoskeletal rearrangements at the cell periphery. |
| Yoram Altshuler (UCSF, CA) |
Arf6 and ARNO regulate dynamin and clathrin dependent endocytosis pathway at the apical surface of MDCK cells |
| Carol Renfrew-Haft (NIDDK/NIH, MD) |
Sorting nexins: mammalian homologues of yeast proteins involved in protein trafficking |
| ALTERNATE PATHWAYS TO AND FROM THE LYSOSOME |
| Discussion Leader: Kurt von Figura |
| Juan Bonifacino (NIH, MD) |
Signal-adaptor interactions in lysosomal targeting |
| Greg Payne (UCLA, CA) |
Alternative signals for endocytic and biosynthetic transport to the vacuole |
| Dan Klionsky (UC Davis, CA) |
Targeting of aminopeptidase I from the cytosol to the vacuole/lysosome |
| Hui-Ling Chiang (Boston, MA) |
Regulation of cytosol-vesicle-vacuole protein targeting pathway in yeast |
| LIPID TRAFFICKING IN THE ENDOCYTIC PATHWAY |
| Discussion Leader: Jean Gruenberg |
| Fred Maxfield (Cornell, NY) |
Endocytic sorting of lipids |
| Rob Parton (Brisbane, Australia) |
Biogenesis of caveolae and T-tubules; lipid-based systems for generation of plasma membrane subdomains |
| James Keen (Thomas Jefferson University, PA) |
Arrestin3 and AP-2 have phosphoinositide binding sites that are required for adaptor function in receptor-mediated endocytosis |
| Gideon Bach (Hadassah University Hospital, Israel) |
Abnormal transport of membranes along the lysosomal pathway in Mucolipidosus type IV disease |
| Michael Brenner (Brigham and Woman's Hospital, Boston) |
Antigen presentation by and trafficking of CD-1 molecules |
| Martin Wiedmann (Sloan Kettering, NY) |
A function for lipoxygenase in programmed organelle degradation |
| ENDOCYTOSIS AND SIGNAL TRANSDUCTION |
| Discussion Leader: John Bergeron |
| Michael Czech (UMASS Worcester, MA) |
Signaling by 3'-polyphosphoinositides through proteins containing Pleckstrin and Sec7 homology domains |
| Silvia Corvera (UMASS, Worcester) |
PI3-Kinase targets in the endocytic pathway |
| Linda Hicke (Northwestern, IL) |
Ubiquitin and phosphorylation-dependent internalization of the alpha-factor receptor in yeast |
| Ger Strous (Utrecht, NL) |
A new endocytosis motif activated by the ubiquitin-proteasome system regulates downregulation of the growth hormone receptor |
| CELLULAR AND VIRAL VIRULENCE FACTORS |
| Discussion Leader: Norma Andrews |
| Alan Aderem (University of Washington, WA) |
Mechanism of Phagolysosome maturation |
| Ralph Isberg (Tufts University, MA) |
Trafficking decisions made by Legionella pneumophila in macrophages |
| Alice Dautry-Varsat (Paris, France) |
Intracellular survival of Chlamydia psittaci in monocytes |
| Dennis Selkoe (Harvard, Boston) |
The Roles of Exocytic and EndocyticTrafficking of APP in Alzheimer's Disease |
| Mark Marsh (London, UK) |
Endocytosis and HIV infection |
| Renate Fuchs (U. Vienna, AU) |
LRP-mediated, clathrin independent entry of human rhinovirus serotype 2 (HRV2) into HeLa cell |
| NOVIKOFF LECTURE |
| Scott Emr (UCSD, CA) |
Sorting out protein trafficking in the yeast secretory pathway |
| Current controversies: an open forum discussion |
Chairs: Sandy Schmid, Hans Geuze, Juan Bonifacino |
