| SUNDAY |
| PM Session | Transport at the trans Golgi |
| Discussion Leader: Greg Payne (University of California, Los Angeles) |
| Juan Bonifacino (National Institutes of Health, Bethesda, MD)
Protein Coats Involved in Sorting at the TGN |
| Gary Thomas (Oregon Health Science Institute, Portland, OR)
The Furin Sorting Pathway and HIV-1 Immunoevasion |
| Suzanne Pfeffer (Stanford University, CA)
Rabs at the late endosome/Golgi interface |
| Vivek Malhotra (University of California, San Diego)
Budding transport carriers from the TGN: Regulation by trimeric G protein and PKD |
| MONDAY |
| AM Session | Protein/Receptor Sorting in the Endosomal/Vacuolar System |
| Discussion Leader: Jim Keen (Thomas Jefferson University, Philadephia, PA) |
| Howard Reizman (Biozentrum-University of Basel, Switzerland)
Role of lipids in the internalization step of Endocytosis or Protein sorting upon exit from the endoplasmic reticulum |
| Marino Zerial (Max Planck Institute, Dresden, Germany)
Rab-domains in endosome organization and function |
| Michel Desjardins (Universite De Montreal/Caprion, Canada)
Endoplasmic reticulum involvement
in phagosome formation and phagolysosome biogenesis |
| Elizabeth Conibear (University of British Columbia, Vancouver, Canada)
Function of the Golgi-Associated Retrograde Protein (GARP) complex in vesicle fusion at the yeast trans-Golgi. |
| Bill Wickner (Dartmouth Medical School, Hanover, NH)
Vacuole Homotypic Fusion Needs 5 SNARES, 4 Chaperones, 3 GTPases, 2 phosphoinositides, and actin |
| Lois Greene (National Institutes of Health, Bethesda, MD)
Adaptor and clathrin exchange at the plasma membrane and trans-Golgi network |
| Randy Schekman (University of California, Berkeley)
Clathrin and AP-1 control the sorting of a set of proteins that cycle between the trans Golgi and early endosome in yeast |
| PM Session | Mechanisms of Endocytosis and Developmental Signaling |
| Discussion Leader: Alexander Sorkin (University Colorado, Boulder, CO) |
| Pier Paolo Di Fiore (European Institute of Oncology, Milano, Italy)
Differential regulation of ligand-induced versus constitutive endocytosis by proteins of the EH network |
| Temo Kurzchalia (Max Planck Institute, Dresden, Germany)
Physiology of caveolae-deficient mice |
| Harvey McMahon (Medical Research Council, Cambridge, UK)
Protein Lipid Interactions in Clathrin-mediated endocytosis |
| Marc Muskavitch (Boston College, MA)
Endocytic Elements of Delta-Notch Signalling |
| TUESDAY |
| AM Session | Ubiquitin and Phosphoinositides in Endocytosis and Endosomal Sorting |
| Discussion Leader: Ann Hubbard (Johns Hopkins Medical School, Baltimore, MD) |
| Linda Hicke (Northwestern University, Chicago, IL)
The functions of ubiquitin-binding proteins in the endocytic pathway |
| Beverly Wendland (Johns Hopkins University, Baltimore, MD)
Domain analysis and regulation of the yeast epsins |
| Ger Strous (Utrecht University, The Netherlands)
Growth Hormone Receptor Traffic Control |
| Chris Stefan (University of California, San Diego)
Essential role for PI3P and ubiquitin in MVB sorting |
| Philip Woodman (University of Manchester, UK)
Mammalian Class E VPS Proteins and Endocytic Sorting |
| Harald Stenmark (The Norwegian Radium Hospital, Montebello, Norway)
Role for HRS in endosomal sorting |
| PM Session | Mechanisms of Autophagy |
| Discussion Leader: Suresh Subramani (University of California, San Diego) |
| Daniel Klionsky (University of Michigan, Ann Arbor)
Regulation of autophagy in yeast |
| Yoshinori Ohsumi (National Institute for Basic Biology, Okazaki, Japan)
Components of the autophagy machinery |
| Suresh Subramani (University of California, San Diego)
Peroxisome turnover by autophagy |
| Patrice Codogno (INSERM U504, Cedex, France)
Regulation of mammalian macroautophagy |
| Beth Levine (Columbia University, New York, NY)
Autophagy Regulation by Evolutionarily Conserved Signaling Pathways |
| WEDNESDAY |
| AM Session | Viral Budding and Sorting at the Late Endosome/MVB |
| Discussion Leader: Carol Carter (SUNY at Stony Brook, NY) |
| Ira Mellman (Yale University School of Medicine, New Haven, CT)
Protein Sorting in Polarized Epithelial Cells |
| Eva Neuhaus (Ruhr-Universitat Bochum, Germany)
Role of a myosin I in the maturation of macropinosomes and phagosomes |
| Yosef Yarden (Wiezmann Institute of Science, Israel)
Targeting of Oncogenic Receptors in Degradation |
| Sudha Shenoy (Duke University, Durham, NC)
Roles of b-arrestin and receptor ubiquitination in G-protein coupled receptor trafficking |
| Carol Carter (SUNY at Stony Brook, NY)
Tsg101 and Nedd4 Roles in Retroviral Budding |
| Wesley Sundquist (University of Utah School of Medicine)
Tsg101 and Vacuolar Protein Sorting in HIV-1 Budding |
| PM Session | Structural Studies along the Endocytic Pathway |
| Discussion Leader: Tom Kirchhausen (Harvard, Boston, MA) |
| Michael Overduin (University of Colorado Health Sciences Center, Denver)
Biological NMR studies of membrane and protein recognition in endocytosis and signal transduction |
| Jenny Hinshaw (National Institutes of Health, Bethesda, MD)
The Three Dimensional Structure of Dynamin in the Constricted State |
| James H. Hurley (National Institutes of Health, Bethesda, MD)
Sorting receptors and VHS domains: recognition and phosphoregulation |
| David Owen (University of Cambridge, CIMR, UK)
The molecular architecture and function of the endocytic AP2 complex |
| THURSDAY |
| AM Session | Pathogens and Disorders in the Endosomal/Lysosomal System |
| Discussion Leader: Caroline Enns (Oregon Health and Science University, Portland, OR) |
| Barth D. Grant (Rutgers University, New Brunswick, NJ)
Endocytosis and Recycling in Caenorhabditis Elegans |
| Michael Marks (University of Pennsylvania, Philaelphia, PA)
Biogenesis of Melanosomes and their precursors |
| Lucas Pelkmans (Swiss Federal Institute of Technology, Zurich, Switzerland)
Caveolar endocytosis of Simian Virus 40 |
| Alice Dautry-Varsat (Institut Pasteur, Paris France)
Chlamydia infection and its interactions with Host cells or Trafficking of IL2 and T cell Receptors |
| Norma Andrews (Yale University School of Medicine, New Haven, CT)
Regulated exocytosis of lysosomes |
| Jan Cerny (Harvard Medical School, CBR, Boston, MA)
Perturbations in the endosomal system by Chemical Genetics |
| PM Session | Alex Novikoff Lecture |
| Pietro De Camilli (Yale University School of Medicine, New Haven, CT)
Molecular mechanisms in endocytosis at the synapse |
| | Reception at the old chapel |
