SUNDAY |
4:00 pm - 8:00 pm | Arrival and Check-in (Check-in Desk Closed 6:00 pm - 7:45 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | MALARIA CONTROL, ELIMINATION OR ERADICATION |
| Discussion Leader: Sir Richard Feachem (University of California, San Francisco) |
7:40 pm - 8:20 pm | Pedro Alonso (University of Barcelona)
"Control versus Eradication: which agenda, which tools" |
8:20 pm - 8:35 pm | Discussion |
8:35 pm - 9:15 pm | Anthony James (University of California, Irvine)
"Vector biology and the malaria eradication agenda" |
9:15 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | MALARIA EPIDEMIOLOGY AND MODELING |
| Discussion Leader: W. Ripley Ballou (GlaxoSmithKline Biologicals) |
9:00 am - 9:30 am | Jean-Francois Trape (Institut de Recherche pour le Développement)
"Malaria's changing epidemiology" |
9:30 am - 9:45 am | Discussion |
9:45 am - 10:15 am | Simon Hay (Oxford University)
"Using maps to help put confidence intervals on malaria models" |
10:15 am - 10:30 am | Discussion |
10:30 am | Coffee Break / Group Photo |
11:00 am - 11:30 am | Tom Smith (Swiss Tropical Institute)
"Mathematical models and planning for elimination" |
11:30 am - 11:45 am | Discussion |
11:45 am - 12:15 pm | Philip Eckhoff (Intellectual Ventures)
"New tools for modeling malaria" |
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | TARGETING THE VECTOR - FUTURE TOOLS |
| Discussion Leader: Anthony James (University of California, Irvine) |
5:30 pm - 6:00 pm | Flaminia Catteruccia (Imperial College)
"Sex and reproduction in mosquitoes, and control of malaria transmission" |
6:00 pm - 6:15 pm | Discussion |
6:15 pm - 6:25 pm | Ladslaus Mnyone (Ifakara Health Institute) "Exploiting the behavior of wild malaria vectors to achieve high infection with fungal biocontrol agents" |
6:25 pm - 6:30 pm | Discussion |
6:30 pm - 7:00 pm | Rhoel Dinglasan (Johns Hopkins University) "Transmission-blocking vaccines that target the mosquito" |
7:00 pm - 7:15 pm | Discussion |
7:15 pm - 7:25 pm | Sungano Mharakurwa (Macha Research Trust) "Emergence of Plasmodium falciparum antifolate resistance: the unnoticed role of vector mosquitoes" |
7:25 pm - 7:30 pm | Discussion |
8:00 pm | Dinner |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | SPREAD OF DRUG RESISTANT PARASITES |
| Discussion Leader: Tom Wellems (National Institute of Allergy and Infectious Diseases, NIH) |
9:00 am - 9:30 am | Arjen Dondorp (Mahidol-Wellcome Trust)
"Artemisinin-resistant parasites" |
9:30 am - 9:45 am | Discussion |
9:45 am - 10:15 am | Kevin Baird (Eijkman Oxford Clinical Trials Unit)
"Drug-resistant P. vivax" |
10:15 am - 10:30 am | Discussion |
10:30 am | Coffee Break |
11:00 am - 11:30 am | Elizabeth Winzeler (Novartis Research Foundation, Scripps Research Institute)
"Genetic analysis of drug-resistant parasites" |
11:30 am - 11:45 am | Discussion |
11:45 am - 12:15 pm | Ian Hastings (Liverpool School of Tropical Medicine)
"Evolution of drug resistance" |
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | FUTURE TECHNOLOGIES |
| Discussion Leader: Dyann Wirth (Harvard University) |
5:30 pm - 6:10 pm | David Kaslow (Merck & Co., Inc.)
"Prospects for transmission blocking vaccines for malaria" |
6:10 pm - 6:30 pm | Discussion |
6:30 pm - 7:10 pm | Manuel Llinás (Princeton University)
"Insights from parasite metabolomics" |
7:10 pm - 7:30 pm | Discussion |
8:00 pm | Dinner |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | HOST DIVERSITY |
| Discussion Leader: Dominic Kwiatkowski (Oxford University / Sanger Center) |
9:00 am - 9:40 am | Lucio Luzzatto (Istituto Toscano Tumori)
"Human genetics, disease, and malaria: Implications for interventions" |
9:40 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 11:10 am | David Modiano (University of Rome)
"Human variation and malaria transmission" |
11:10 am - 11:30 am | Discussion |
11:30 am - 12:10 pm | Ken Vernick (Institut Pasteur)
"Mosquito heterogeneity and complexity of malaria transmission" |
12:10 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | FUNCTIONAL GENOMICS OF MALARIA AND VECTOR |
| Discussion Leader: Brendan Crabb (Burnet Institute) |
5:30 pm - 6:00 pm | Philip Felgner (University of California, Irvine) "Predicting humoral immunity to malaria on a genome wide scale" |
6:00 pm - 6:10 pm | Discussion |
6:10 pm - 6:40 pm | Larry Zwiebel (Vanderbilt University)
"The mosquito olfactory system" |
6:40 pm - 6:50 pm | Discussion |
6:50 pm - 7:00 pm | Jonas King (Vanderbilt University) "The SGS protein family forms a major immunogenic component of mosquito saliva" |
7:00 pm - 7:05 pm | Discussion |
7:05 pm - 7:20 pm | Karine LeRoch (University of California, Riverside) "Epigenomics and virulence in the human malaria parasites: a system biology approach to understand the parasite infection cycle" |
7:20 pm - 7:30 pm | Discussion |
7:30 pm - 8:00 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
8:00 pm | Dinner |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | MALARIA IMMUNOPATHOGENESIS AND IMMUNITY |
| Discussion Leader: Odile Puijalon (Institut Pasteur) |
9:00 am - 9:30 am | Douglas Golenbock (University of Massachusetts Medical School) "Sensing AT-rich DNA stem-loop motif causes inflammation during malaria" |
9:30 am - 9:40 am | Discussion |
9:40 am - 9:55 pm | Silvia Portugal (National Institute of Allergy and Infectious Diseases, NIH) "Upregulation of Plasmodium falciparum-specific anti-inflammatory response after acute malaria" |
9:55 pm - 10:00 pm | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:45 am | Leyla Bustamante (Evimalar, Wellcome Trust Sanger Institute) "A systematic screen identifies an erythrocyte receptor that is essential for Plasmodium falciparum invasion" |
10:45 am - 10:50 am | Discussion |
10:50 am - 11:05 am | Gladys Keitany (Seattle Biomedical Research Institute) "A conserved Plasmodium falciparum protein mediates placental sequestration of malaria parasites" |
11:05 am - 11:10 am | Discussion |
11:10 am - 11:25 am | Sophie Uyoga (Evimalar, University of Torino) "Transfer of 4-hydroxynonenal from parasitized to non-parasitized erythrocytes in rosettes. Role in severe malaria anemia." |
11:25 am - 11:30 am | Discussion |
11:30 am - 11:45 am | Michal Fried (National Institute of Allergy and Infectious Diseases, NIH) "Plasmodium falciparum parasites that cause severe malaria bind the extracellular matrix molecule laminin" |
11:45 am - 11:50 am | Discussion |
11:50 am - 12:05 pm | Freya Fowkes (Burnet Institute) "Using antibodies as markers of exposure to malaria during pregnancy in low transmission settings" |
12:05 pm - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | Bartholomew Nyangahu (Maseno University) "Stable antibody frequencies to MSP-142 and GLURP-R2 in a period of absent malaria in highland areas unstable seasonal transmission, western Kenya" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | INTERRUPTING TRANSMISSION |
| Discussion Leader: Allan Saul (Novartis Vaccines Institute) |
5:30 pm - 5:45 pm | Bakary Fofana (University of Bamako) "Impact of Artemisinin-based combination therapy on malaria transmission in Mali"
|
5:45 pm - 5:50 pm | Discussion |
5:50 pm - 6:05 pm | Elizabeth Nardin (New York University School of Medicine)
"P. falciparum Circumsporozoite repeat peptide conjugated to meningococcal outer membrane protein complex elicits sporozoite neutralizing antibodies in mice and rhesus monkeys"
|
6:05 pm - 6:10 pm | Discussion |
6:10 pm - 6:30 pm | Sebastian Mikolajczak (Seattle Biomedical Research Institute) "Towards improved models for P. falciparum liver stage infection" |
6:30 pm - 6:40 pm | Discussion |
6:40 pm - 7:15 pm | Robert Sauerwein (University Medical Centre Nijmegen) "Live organism vaccination for malaria" |
7:15 pm - 7:30 pm | Discussion |
8:00 pm | Dinner |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |