Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: A Pivot Point for Malaria Treatment, Control and Eradication
Discussion Leader: Faith Osier (Imperial College London, United Kingdom)
7:40 pm - 8:05 pm
Abdisalan Noor (World Health Organization, Switzerland)
"Malaria Eradication: Facts, Factions and the Future"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
Kevin Marsh (University of Oxford, United Kingdom)
"Malaria Vaccines, Looking Back, Looking Forward"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
Ify Aniebo (HSDF & African Centre of Excellence for Genomics of Infectious Diseases (ACEGID) , Nigeria)
"Country Ownership in Global Health"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Visualizing Malaria Pathogenesis: The Real Deal versus Model Systems
Discussion Leader: Sam Wassmer (London School of Hygiene & Tropical Medicine, United Kingdom)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
Christopher Moxon (University of Glasgow, United Kingdom)
"Explosions and Broken Barriers: Neutrophils and The Brain in Human Cerebral Malaria"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
Mara Lawniczak (Wellcome Sanger Institute, United Kingdom)
"The Malaria Cell Atlas and its Utility for Exploring Transmission Biology in Endemic Settings"
9:55 am - 10:05 am
Discussion
10:05 am - 10:35 am
Coffee Break
10:35 am - 10:55 am
Chet Joyner (University of Georgia, United States)
"Using Nonhuman Primate Models of Malaria to Understand 'The Real Deal'"
10:55 am - 11:05 am
Discussion
11:05 am - 11:15 am
Brandon Wilder (Oregon Health and Science University, United States)
"Plasmodium-Specific, Liver-Resident Immunity at the Single Cell Level During Whole Sporozoite Immunization in Non-Human Primates"
11:15 am - 11:20 am
Discussion
11:20 am - 11:40 am
Kevin Couper (University of Manchester, United Kingdom)
"Pathways Controlling the Development and Recovery from Experimental Cerebral Malaria"
11:40 am - 11:50 am
Discussion
11:50 am - 12:10 pm
Maria Bernabeu (EMBL Barcelona, Spain)
"Modelling Cerebral Malaria with 3D Blood-Brain Barrier Models"
12:10 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizers: Kim Lindblade (PATH, Switzerland) and Amy Bei (Yale School of Public Health, United States)
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Malaria Pathogenesis
Discussion Leader: Chandy John (Indiana University School of Medicine, United States)
6:00 pm - 6:05 pm
Introduction by Discussion Leader
6:05 pm - 6:20 pm
Kamija Phiri (Kamuzu University of Health Sciences, Malawi)
"Severe Malarial Anaemia: Pathogenesis to Prevention"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:45 pm
Andrea Conroy (Indiana University School of Medicine, United States)
"Exposing the Silent Burden and Consequences of Acute Kidney Injury in Pediatric Severe Malaria"
6:45 pm - 6:55 pm
Discussion
6:55 pm - 7:10 pm
Richard Idro (Makerere University College of Health Sciences, Uganda)
"Pathogenesis of Cerebral Malaria; Any New Insights?"
7:10 pm - 7:20 pm
Discussion
7:20 pm - 7:30 pm
Nuria Sima Teruel (Barcelona Institute for Global Health (ISGlobal), Hospital Clínic - Universitat de Barcelona, Spain)
"Organ-on-a-Chip Technology to Study Extracellular Vesicles Mediated Cryptic Infections in Malaria"
7:30 pm - 7:35 pm
Discussion
7:35 pm - 7:50 pm
Julie Gutman (Centers for Disease Control and Prevention, United States)
"Malaria in Pregnancy: What Comes Next?"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Enhancing Antimalarial Immunity, Up to But Not Including Vaccines
Discussion Leader: Yaw Bediako (Yemaachi Biotech, Ghana)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
Prasanna Jagannathan (Stanford University, United States)
"Immunologic Consequences of Early Life Malaria Exposure"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
Faith Osier (Imperial College London, United Kingdom)
"IgG Fc-Mediated Mechanisms are Strong Predictors of Protection against Plasmodium Falciparum Malaria"
9:55 am - 10:05 am
Discussion
10:05 am - 10:35 am
Coffee Break
10:35 am - 10:55 am
Teun Bousema (Radboud University Medical Center, The Netherlands)
"Strong Transmission-blockade or Weak Gametocyte Responses: Understanding Naturally Acquired Sexual Stage Immunity to P. falciparum "
10:55 am - 11:05 am
Discussion
11:05 am - 11:15 am
Gonzalo Acevedo (University of California, San Francisco, United States)
"Targets of CD4 T Cell Responses Against Liver Stage P. falciparum Antigens in Ugandan Children Exposed to Malaria"
11:15 am - 11:20 am
Discussion
11:20 am - 11:40 am
Hedda Wardemann (German Cancer Research Center, Germany)
"Immune Response to Plasmodium falciparum Circumsporozoite Protein"
11:40 am - 11:50 am
Discussion
11:50 am - 12:00 pm
Kayentao Kassoum (University of Sciences, Techniques and Technologies of Bamako, Mali)
"Safety and Efficacy of Anti-Sporozoite Monoclonal Antibodies in Africa"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:20 pm
General Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Vaccine-Mediated Immunity
Discussion Leader: Ashley Birkett (PATH, United States)
6:00 pm - 6:05 pm
Introduction by Discussion Leader
6:05 pm - 6:20 pm
Georgia Tomaras (Duke, United States)
"Antibody Dynamics as Correlates of Protection"
6:20 pm - 6:25 pm
Discussion
6:25 pm - 6:40 pm
Neville Kisalu (PATH, United States)
"Identification of RTS,S Biomarkers Associated with Protection to Guide the Development of Next-Generation Malaria Vaccines"
6:40 pm - 6:45 pm
Discussion
6:45 pm - 7:00 pm
Michelle Boyle (Burnet Institute, Australia)
"Host-directed Treatment to Improve Anti-parasitic Immunity in Volunteers Experimentally Infected with Blood-stage Malaria"
7:00 pm - 7:05 pm
Discussion
7:05 pm - 7:20 pm
Adrian Hill (University of Oxford, United Kingdom)
"Progress with Malaria Vaccines Against Sporozoites"
7:20 pm - 7:25 pm
Discussion
7:25 pm - 7:40 pm
Simon Draper (University of Oxford, United Kingdom)
"Timing Is ... Well, Not Everything, But is Important"
7:40 pm - 7:50 pm
Discussion
7:50 pm - 8:00 pm
General Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Advances in Vector Biology
Discussion Leader: Mara Lawniczak (Wellcome Sanger Institute, United Kingdom)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:35 am
Flaminia Catteruccia (Harvard T.H. Chan School of Public Health, United States)
"Blood, Drugs and Parasites: Blocking Plasmodium Transmission by Anopheles Mosquitoes"
9:35 am - 9:50 am
Discussion
9:50 am - 10:20 am
Elena Levashina (Max Planck Institute for Infection Biology, Germany)
"Targeting Malaria Parasites Inside the Mosquito Vector"
10:20 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:15 am
Tanwee Das De (Indian Institute of Science Education and Research, India)
"Chronobiology of Mosquito Olfaction: Understanding the Differential Molecular Rhythm and Perireceptor Events of Diurnal and Nocturnal Mosquitoes"
11:15 am - 11:20 am
Discussion
11:20 am - 11:50 am
Marta Ferreira Maia (KEMRI Wellcome Trust, Kenya)
"MALDI TOF MS for Malaria Vector Surveillance"
11:50 am - 12:05 pm
Discussion
12:05 pm - 12:15 pm
Christine Markwalter (Duke University, United States)
"Quantifying Female Anopheline Biting Bias in a Community Setting with High Transmission of Plasmodium Falciparum in Western Kenya"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Identifying, Tracking and Treating Silent Reservoirs of Infection
Discussion Leader: Brian Greenwood (London School of Hygiene & Tropical Medicine, United Kingdom)
6:00 pm - 6:05 pm
Introduction by Discussion Leader
6:05 pm - 6:25 pm
Alassane Dicko (MRTC- University of Bamako, Mali)
"Protection Against Seasonal Malaria for Five Years with Vaccination and Chemoprevention"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
Lauren Cohee (University of Maryland School of Medicine, United States)
"School-Age Children as Reservoirs of Infection and Targets for Transmission Reduction"
6:50 pm - 6:55 pm
Discussion
6:55 pm - 7:15 pm
Steven Kho (Menzies School of Health Research, Australia)
"Hidden Splenic Reservoirs of Plasmodium Falciparum and Plasmodium Vivax "
7:15 pm - 7:20 pm
Discussion
7:20 pm - 7:30 pm
Jordi Landier (IRD - French National Research Institute for Sustainable Development, France)
"Seasonal Dynamics of Plasmodium Falciparum Asymptomatic Reservoir in Sahelian Africa"
7:30 pm - 7:35 pm
Discussion
7:35 pm - 7:55 pm
Photini Sinnis (Johns Hopkins Bloomberg School of Public Health, United States)
"Changing the Epidemiological Paradigm: Parasite Numbers in the Mosquito Matter"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Malaria Morbidity: The Burden of Disease in Survivors
Discussion Leader: Ruth Namazzi (Makerere University College of Health Sciences, Uganda)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
Chandy John (Indiana University School of Medicine, United States)
"Long-Term Complications of Severe Malaria: A Hidden Burden"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
Gretchen Birbeck (UNIVERSITY OF ROCHESTER, United States)
"Malarial Epileptogenesis: The Pathophysiology and Epidemiology of Malaria’s Contribution to the Global Burden of Epilepsy"
9:55 am - 10:05 am
Discussion
10:05 am - 10:35 am
Coffee Break
10:35 am - 10:45 am
Karen Jacobson (Stanford School of Medicine, United States)
"Association Between Malaria Parasitemia and SARS-CoV-2 Infection in Pregnant Ugandan Women Enrolled in a Malaria Chemoprevention Trial"
10:45 am - 10:50 am
Discussion
10:50 am - 11:10 am
Paul Bangirana (Makerere University, Uganda)
"Malaria Effect on the Brain: Studies from Prenatal to Early Adulthood"
11:10 am - 11:20 am
Discussion
11:20 am - 11:40 am
Amina Abubakar (Aga Khan University, Kenya)
"Neurobehavioral Sequelae of Malaria Infection: Recent Advances and Future Opportunities"
11:40 am - 11:50 am
Discussion
11:50 am - 12:10 pm
Ryan D'Arcy (HealthTech Connex, Canada)
"Can’t Treat What You Can’t Measure: Portable Brain Vital Sign Evaluation of Computer-Based Cognitive Rehabilitation in Brain Injury and Disease"
12:10 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Keynote Session: Anticipating Opportunities and Challenges
Discussion Leader: Ify Aniebo (HSDF & African Centre of Excellence for Genomics of Infectious Diseases (ACEGID) , Nigeria)
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:40 pm
Abdoulaye Djimde (University of Sciences, Techniques and Technologies of Bamako, Mali)
"Malaria Genomics Diversity: From Public Health To Single Cell"
6:40 pm - 6:55 pm
Discussion
6:55 pm - 7:05 pm
Don Mathanga (Kamuzu University of Health Sciences, Malawi)
"Barriers to Bednet Use"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:30 pm
Kenny Evans (McCann Health New York, United States)
"Overcoming Barriers to Bednet Use"
7:30 pm - 7:40 pm
Discussion
7:40 pm - 7:55 pm
General Discussion
7:55 pm - 8:00 pm
Closing Remarks
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure