| Saturday |
| 1:30 pm - 4:30 pm | Arrival and Check-in |
| 3:00 pm - 3:15 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:15 pm - 4:00 pm | Transmission
and Epidemiology |
| Discussion Leaders: Robert Sauerwein (Radboud University Medical Center, The Netherlands) and Raul Saraiva (Johns Hopkins Bloomberg School of Public Health, USA) |
| 3:15 pm - 3:25 pm | Giulia Costa (Max Planck Institute for Infection Biology, Germany)
"Role of Mosquito Nutrient Transporters in Reproduction and Plasmodium Transmission" |
| 3:25 pm - 3:30 pm | Discussion |
| 3:30 pm - 3:40 pm | Raul Saraiva (Johns Hopkins Bloomberg School of Public Health, USA)
"Anti-Plasmodium Mechanisms of a Natural Chromobacterium Mosquito Midgut Commensal" |
| 3:40 pm - 3:45 pm | Discussion |
| 3:45 pm - 3:55 pm | Nancy Matowo (Ifakara Health Institute, Tanzania)
"Using a New Odour-Baited Device to Explore Options for Luring and Killing Outdoor-Biting Malaria Vectors: Design and Field Evaluation of the Mosquito Landing Box" |
| 3:55 pm - 4:00 pm | Discussion |
| 4:00 pm - 5:30 pm | Poster Session |
| 5:30 pm - 7:30 pm | Vaccine Development and Immunology |
| Discussion Leaders: Simon Draper (Jenner Institute, University of Oxford, United Kingdom) and Monica Rojas-Pena (Georgia Institute of Technology, USA) |
| 5:30 pm - 5:40 pm | Lila Farrington (University of California, San Francisco, USA)
"Longitudinal Loss and Dysfunction of Vd2 T-Cells Concurrent with Heavy Malaria Exposure" |
| 5:40 pm - 5:45 pm | Discussion |
| 5:45 pm - 5:55 pm | Qiao Ye Tan (Walter and Eliza Hall Institute, Australia)
"Pre-Clinical Evaluation of Glycosylphosphatidylinositol (GPI) as a Potential Multi-Stage, Pan Species Malaria Vaccine" |
| 5:55 pm - 6:00 pm | Discussion |
| 6:00 pm - 6:10 pm | Monica Rojas-Pena (Georgia Institute of Technology, USA)
"Effect of Pre-Immune Exposure on the Transcriptional Response to Plasmodium vivax in Volunteers from Colombia" |
| 6:10 pm - 6:20 pm | Discussion |
| 6:20 pm - 6:30 pm | Aida Valmaseda (ISGlobal, Spain)
"Characterization of Immune Responses Against the Merozoite Stage of P. falciparum: Association with Protection?" |
| 6:30 pm - 6:35 pm | Discussion |
| 6:35 pm - 6:45 pm | Murad Mamedov (Stanford University, USA)
"T-Cell Activation and Repertoire During Murine Malaria" |
| 6:45 pm - 6:55 pm | Discussion |
| 6:55 pm - 7:05 pm | Joshua Obiero (University of California, Irvine, USA)
"Antibody Responses Associated with Pre-Erythrocytic Immunity Induced by Controlled Human Malaria Infection Under Chloroquine Prophylaxis" |
| 7:05 pm - 7:10 pm | Discussion |
| 7:10 pm - 7:20 pm | Zenon Zenonos (Wellcome Trust Sanger Institute, United Kingdom)
"Basigin Is a Druggable Target for Host-Oriented Anti-Malarial Interventions" |
| 7:20 pm - 7:30 pm | Discussion |
| 8:00 pm | Dinner |
| Sunday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Parasite Biology and Drug Development |
| Discussion Leaders: Alexandra Rowe (University of Edinburgh, United Kingdom) and Silvie Huijben (ISGlobal, Spain) |
| 9:00 am - 9:10 am | Marvin Duvalsaint (University of South Florida, USA)
"Phytohormones and the Role of the Apicoplast in Dormancy in the Erythrocytic Stages of Plasmodium falciparum" |
| 9:10 am - 9:15 am | Discussion |
| 9:15 am - 9:25 am | Silvie Huijben (ISGlobal, Spain)
"The Ecology and Evolution of Drug-Resistant Malaria Parasites" |
| 9:25 am - 9:30 am | Discussion |
| 9:30 am - 9:40 am | Henrietta Mensah-Brown (WACCBIP, University of Ghana, Ghana)
"Analysis of Erythrocyte Invasion Mechanisms of Plasmodium falciparum Clinical Isolates Across Three Endemic Areas Within One Country" |
| 9:40 am - 9:50 am | Discussion |
| 9:50 am - 10:00 am | Heather Painter (Pennsylvania State University, USA)
"Capturing Stage-Specific Transcriptional Dynamics of the Malaria Parasite" |
| 10:00 am - 10:05 am | Discussion |
| 10:05 am - 10:15 am | Michaela Petter (University of Melbourne, Australia)
"A Novel Plasmodium falciparum Bromodomain Protein Regulates Invasion Gene Expression" |
| 10:15 am - 10:25 am | Discussion |
| 10:25 am - 10:35 am | Kim Fong (Vanderbilt University, USA)
"Target Validation of Hemozoin Inhibitors to Understand Drug Mechanism of Action Within Plasmodium falciparum" |
| 10:35 am - 10:40 am | Discussion |
| 10:40 am - 10:50 am | Nanika Coetzee (University of Pretoria, South Africa)
"Qualitative Delineation of the Histone Code of Plasmodium falciparum Across the Entire Asexual and Sexual Life Cycle Reveals Conserved and Unique Post-Translational Signatures" |
| 10:50 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Severe and Pregnancy-Associated Malaria |
| Discussion Leaders: Alfredo Mayor (Barcelona Centre for International Health Research, Spain) and Estela Shabani (University of Minnesota, Twin Cities / Indiana University - Purdue University Indianapolis, USA) |
| 1:30 pm - 1:40 pm | Yvonne Azasi (University of Edinburgh, United Kingdom)
"Lack of Evidence to Support EPCR as a Major Cytoadherence Receptor" |
| 1:40 pm - 1:45 pm | Discussion |
| 1:45 pm - 1:55 pm | Estela Shabani (University of Minnesota, Twin Cities / Indiana University - Purdue University Indianapolis, USA)
"The Endothelial Protein C Receptor (EPCR) rs867186-GG Genotype Is Associated with Increased Levels of Soluble EPCR and Protection from Cerebral Malaria in Ugandan Children" |
| 1:55 pm - 2:00 pm | Discussion |
| 2:00 pm - 2:10 pm | Whitney Harrington (University of Washington / Seattle Children's Hospital, USA)
"MHC Class II Alleles Predict Susceptibility to Placental Malaria and Malaria During Infancy in an East African Cohort" |
| 2:10 pm - 2:15 pm | Discussion |
| 2:15 pm - 2:25 pm | Sarah Boudova (Center for Malaria Research, Institute for Global Health, University of Maryland, Baltimore, USA)
"The Effect of Malaria During Pregnancy on Infant Susceptibility to Malaria" |
| 2:25 pm - 2:30 pm | Discussion |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
| 3:00 pm | Seminar Concludes |
