Frontiers of Mammalian Genomic Stability in Human Health

The DNA in our cells constantly changes its structure and chemical composition in the course of endogenous processes and in response to exogenous challenges. The 2017 Mammalian DNA Repair GRC will expose researchers at all levels (faculty, researchers from industry, postdoctoral fellows, graduate students) to new frontiers of this rapidly progressing research field. DNA repair pathways are intimately linked to genome sequence and all aspects of DNA metabolism from replication, transcription to dynamic chromatin structural changes throughout the cell cycle. This meeting will focus on the balance between the normal cellular processes and DNA repair events in mammals to illustrate how genome integrity is safeguarded and what causes various types of instability and malady.

The speakers will outline new ideas, approaches and results at the frontiers of DNA mammalian repair. Many of the invited speakers are outstanding women scientists and young faculty. In addition, several long and many short talks will be selected from the abstract submissions. Trainees will have ample opportunities to give oral presentations and to lead and participate in both formal and informal discussions. We aim to have an open, lively and delightful atmosphere for scientific exchange and making personal connections.