Mechanisms and Consequences of Genome Instability

Genomic DNA is constantly exposed to endogenous and exogenous DNA damaging agents and if left unrepaired, DNA damage can lead to mutagenesis and genomic instability. Cells have evolved specific DNA repair pathways to recognize and remove DNA damage. Defects in these repair pathways are associated with several pathologies such as cancer and neurodegeneration.

This year, the Mammalian DNA Repair GRS will be focused on understanding the mechanisms of DNA repair and the consequences of DNA damage on the genome. Additionally, the oral and poster presentations will encourage discussions on recent or unpublished developments in the field of mammalian DNA repair. The program includes a keynote seminar by a leading expert in the field and a mentorship component which will allow participants to interact with panelists from diverse scientific areas including academia, industry, science communication and publishing.