Sunday |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Environmental Impacts upon Reproduction and
Offspring Health |
| Discussion Leader: Amander Clark (University of California, Los Angeles, USA) |
7:40 pm - 7:50 pm | Introduction by Discussion Leader |
7:50 pm - 8:15 pm | Patricia Hunt (Washington State University, USA) "The Perils of Making Gametes in the 21st Century" |
8:15 pm - 8:25 pm | Discussion |
8:25 pm - 8:50 pm | Jodi Flaws (University of Illinois, USA) "Environmental Chemicals and the Female Reproductive System" |
8:50 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Douglas Kwon (Massachusetts Institute of Technology / Harvard University, USA) "The Role
of Genital Inflammation and the Vaginal Microbiome in HIV Acquisition Risk" |
9:20 pm - 9:30 pm | Discussion |
Monday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Genetic Regulation of Reproductive Outcomes |
| Discussion Leader: Margaret (Peggy) Petroff (Michigan State University, USA) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Kjersti Aagaard (Baylor College of Medicine, USA) "Unexpected
Beginnings: How the Intrauterine and Maternal Microbial and Metabolic Environments
Influence Offspring Health" |
9:35 am - 9:45 am | Discussion |
9:45 am - 10:10 am | Alex Bortvin (Carnegie Institution for Science, USA) "Sex-Specific
Strategies and Outcomes of Transposon Control in Germ Cells" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:30 am | Wenfeng An (South Dakota State University, USA) "The Missing Link Between Retrotransposon Activation and Meiotic Failure in piRNA-Deficient Mice" |
10:30 am - 10:35 am | Discussion |
10:35 am - 11:05 am | Group Photo / Coffee Break |
11:05 am - 11:15 am | Kathryn Grive (Cornell University, USA) "TAF4b Regulates Oocyte-Specific Genes Essential for Meiosis and Primordial Follicle Development" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:30 am | Hieu Nguyen (University of Hawaii at Manoa, USA) "A New Found Function of the DNA Licensing Protein ORC4 on Polar Body Extrusion" |
11:30 am - 11:35 am | Discussion |
11:35 am - 12:00 pm | Monika Ward (University of Hawaii, USA) "To Be or
Not to Be: Essential and Not So Essential Roles of Mouse Y Chromosome Genes in
Germline Regulation" |
12:00 pm - 12:10 pm | Discussion |
12:10 pm - 12:20 pm | Sylvia Hewitt (National Institute of Environmental Health Sciences, NIH, USA) "Negative Elongation Factor Subunit B (NELF-B) Is Essential for Endometrial Function" |
12:20 pm - 12:25 pm | Discussion |
12:25 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
3:00 pm - 4:00 pm | Power Hour |
| The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring. |
| Organizer: Margaret (Peggy) Petroff (Michigan State University, USA) |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Editing the Genes of Gametes and Embryos |
| Discussion Leader: Francesco Demayo (National Institute of Environmental Health Sciences, NIH, USA) |
7:30 pm - 7:40 pm | Introduction by Discussion Leader |
7:40 pm - 8:05 pm | John Schimenti (Cornell University, USA) "Genetic Variation and Human Fertility" |
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | F. Kent Hamra (Universtity of Texas Southwestern Medical Center, USA) "Integrating
Genome Editing Technologies into Robust Rattus norvegicus Spermatogenesis
Colony Forming Assays" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Randall Prather (University of Missouri-Columbia, USA) "Editing the Pig Genome for Agriculture and Biomedicine" |
9:15 pm - 9:25 pm | Discussion |
9:25 pm - 9:30 pm | General Discussion |
Tuesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Epigenetic Regulation in Reproduction |
| Discussion Leader: John McCarrey (University of Texas at San Antonio, USA) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Marisa Bartolomei (University of Pennsylvannia, USA) "Regulation of Genomic Imprinting in
Development and Disease" |
9:35 am - 9:45 am | Discussion |
9:45 am - 10:10 am | Myriam Hemberger (Babraham Institute, United Kingdom) "Epigenetic and Transcriptional Networks Controlling Trophoblast Stem
Cells – The Stepping Stone for Normal Placentation and Reproductive Health" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:30 am | Felipe Vilella (FundaciĆ³n IVI / INCLIVA, Spain) "Maternal Endometrial Hsa-miR-30d Is Necessary for Embryo Implantation" |
10:30 am - 10:35 am | Discussion |
10:35 am - 11:05 am | Coffee Break |
11:05 am - 11:15 am | Steen Ooi (University College London, United Kingdom) "A Novel Role for Microprocessor Component Drosha in Cytosine Methylation" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:30 am | Qi Chen (University of Nevada, Reno School of Medicine, USA) "Sperm tsRNAs and RNA Modifications in Diet-Induced Epigenetic Inheritance" |
11:30 am - 11:35 am | Discussion |
11:35 am - 12:00 pm | Sue Hammoud (University of Michigan Medical School, USA) "Chromatin Dynamics and Its Role in Developing Germ Cells" |
12:00 pm - 12:10 pm | Discussion |
12:10 pm - 12:20 pm | Christopher Payne (Feinberg School of Medicine, Northwestern University, USA) "Dicer1-Mediated Silencing of INSM1 in Spermatogonia Permits the Expression of PHD Finger Protein 1 and Global Polycomb Group Methyltransferase Activity" |
12:20 pm - 12:25 pm | Discussion |
12:25 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Stem Cells in Reproduction |
| Discussion Leader: Wei Yan (University of Nevada School of Medicine, USA) |
7:30 pm - 7:40 pm | Introduction by Discussion Leader |
7:40 pm - 8:05 pm | Jan Brosens (University of Warwick, United Kingdom) "Endometrial Stem Cell Deficiency and Recurrent Pregnancy Loss" |
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | Brian Hermann (University of Texas at San Antonio, USA) "Defining the Mammalian Spermatogonial Stem Cell Pool" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Harry Leitch (MRC Clinical Sciences Centre, Medical Research Council, United Kingdom) "Nanog, Pluripotency and the Germline Revisited" |
9:15 pm - 9:25 pm | Discussion |
9:25 pm - 9:30 pm | General Discussion |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Bioengineering and Reproductive Health |
| Discussion Leader: Kyle Orwig (University of Pittsburgh, USA) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Daniela Ulrich (Medical University of Graz, Austria) "Bioengineering
of the Lower Female Reproductive Tract - New Approaches for Treating Pelvic
Organ Prolapse" |
9:35 am - 9:45 am | Discussion |
9:45 am - 10:10 am | Mats Hellstrom (University of Gothenburg, Sweden) "Uterus Transplantation Followed by Bioengineering of the Uterus" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:30 am | Yasushi Hirota (The University of Tokyo, Japan) "STAT3 Promotes Uterine Regeneration in a Mouse Model of Decellularized Uterine Matrix Transplantation" |
10:30 am - 10:35 am | Discussion |
10:35 am - 11:05 am | Coffee Break |
11:05 am - 11:15 am | Chris Geyer (East Carolina University, USA) "Retinoid Catabolism Regulates Spermatogonial Fate in the Mouse Testis" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:30 am | Enrique Sosa (University of California, Los Angeles, USA) "Developing a Non-Human Primate Model for Stem Cell and Germline Research" |
11:30 am - 11:35 am | Discussion |
11:35 am - 12:00 pm | Joanna Burdette (University of Illinois at Chicago, USA) "Engineering
the Female Reproductive Tract Using Microfluidics" |
12:00 pm - 12:10 pm | Discussion |
12:10 pm - 12:20 pm | Ripla Arora (University of California, San Francisco, USA) "Imaging the Implanting Embryo and the Uterine Environment in Three-Dimensions" |
12:20 pm - 12:25 pm | Discussion |
12:25 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | Reproductive Transcription and Signaling Pathways |
| Discussion Leader: Diana Laird (University of California, San Francisco, USA) |
7:30 pm - 7:40 pm | Introduction by Discussion Leader |
7:40 pm - 8:05 pm | Blanche Capel (Duke University, USA) "Committing to Testis or Ovary Fate" |
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | Shuangbo Kong (State Key Laboratory of Stem Cell and Reproductive Biology, China) "Molecular Determinants of Uterine Receptivity" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Aleksandar Rajkovic (University of Pittsburgh, USA) "Reproductive Aging and
Overall Health: Is There a Link?" |
9:15 pm - 9:25 pm | Discussion |
9:25 pm - 9:30 pm | General Discussion |
Thursday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Continuing Challenges to Human Reproductive
Health |
| Discussion Leader: Xiujun Fan (Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, China) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Jacquetta Trasler (McGill University, Canada) "Epigenetic Targets of
Environmental and Drug Exposures in Germ Cells and Embryos" |
9:35 am - 9:45 am | Discussion |
9:45 am - 10:10 am | Michal Neeman (Weizmann Institute of Science, Israel) "Recent Developments in MRI Analysis of Maternal Angiogenesis During Early
Pregnancy in Mice" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:30 am | Ernesto Figueiro-Filho (Federal University of Mato Grosso do Sul, Brazil) "White Matter Diffusion Tensor Imaging (DTI) and Resting State Functional Connectivity (rs-fMRI) Differ in Children Born from Preeclamptic Gestations" |
10:30 am - 10:35 am | Discussion |
10:35 am - 11:05 am | Coffee Break |
11:05 am - 11:15 am | Melissa Pepling (Syracuse University, USA) "Oocyte Survival and Follicle Formation in an Estrogen Deficient Environment" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:30 am | Nava Dekel (Weizmann Institute of Science, Israel) "Hyaluronic Acid: Anti-Angiogenic Shield for the Post-Implantation Embryo" |
11:30 am - 11:35 am | Discussion |
11:35 am - 12:00 pm | Andrew Sharkey (University of Cambridge, United Kingdom) "HLA-KIR Associations in Human Reproductive Success" |
12:00 pm - 12:10 pm | Discussion |
12:10 pm - 12:20 pm | Gunter Wagner (Yale University, USA) "The Role of Inflammation in the Evolution of Mammalian Pregnancy" |
12:20 pm - 12:25 pm | Discussion |
12:25 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | Keynote Session: Milestones in Reproductive
Biology |
| Discussion Leaders: Jon Oatley (Washington State University, USA) and Humphrey Yao (National Institute of Environmental Health Sciences, NIH, USA) |
5:30 pm - 5:40 pm | Introduction by Discussion Leader |
5:40 pm - 6:10 pm | Mitch Eddy (National Institute of Environmental Health Sciences, NIH, USA) "The Ark of Life: The Germ
Line - Past, Present and Future" |
6:10 pm - 6:25 pm | Discussion |
6:25 pm - 6:35 pm | Introduction by Discussion Leader |
6:35 pm - 7:05 pm | Marilyn Renfree (University of Melbourne, Australia) "Reproduction
Down Under: The 6% Solution" |
7:05 pm - 7:20 pm | Discussion |
7:20 pm - 7:25 pm | General Discussion |
7:25 pm - 7:30 pm | Closing Remarks |
8:00 pm | Dinner |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |