Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Forefronts and Lessons in Reproduction
Discussion Leader: Yong Song (Michigan State University, United States)
3:45 pm - 3:50 pm
Introduction by Discussion Leader
3:50 pm - 4:05 pm
Joan Jorgensen (University of Wisconsin-Madison, United States)
"Here by Accident: Don’t be Afraid to Notice an Unanticipated Open Door"
4:05 pm - 4:10 pm
Discussion
4:10 pm - 4:25 pm
Kyle Orwig (University of Pittsburgh, United States)
"Fertility Preservation for Kids"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Developmental Mechanisms Driving Successful Reproduction
Discussion Leaders: Omar Jose (National Institutes of Health, United States) and Amy Winship (Monash Biomedicine Discovery Institute, Australia)
7:30 pm - 7:45 pm
Bruna Tatematsu (Loyola University Chicago, United States)
"Regulation of Uterine NK Cell Subsets by Reproductive Hormones"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Matthew Shannon (University of British Columbia, Canada)
"Modeling Human Trophoblasts: A Single-Cell Transcriptomic Characterization"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Ruby Boateng (The Jackson Laboratory, United States)
"Comparative Analysis of Oocyte Development in Female Mice with Different Genetic Backgrounds"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Shafqat Khan (Washington University School of Medicine, United States)
"Enhanced Naïve Pluripotent Stem Cells for Modelling Early Human Development"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Rexxi Prasasya (University of Pennsylvania, United States)
"Investigating Active Demethylation Pathways in Germline Epigenetic Reprogramming Using Novel Tet1 Mouse Mutants"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Neha Gupta (University of Massachusettes, United States)
"Is There a Second Sperm Factor in Mouse Sperm?"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Impacts of Disease, Damage and Aging on Reproduction
Discussion Leaders: In Cho (University of Georgia, United States) and Claire Stenhouse (Texas A&M University, United States)
9:00 am - 9:15 am
Gregory Burns (Michigan State University, United States)
"FOXC1 Functions as a Proinflammatory Transcriptional Regulator in Endometriotic Lesions"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Lauren Alesi (Monash University, Australia)
"The Trials and Tribulations of Blocking PUMA for Fertility Preservation Against Chemotherapy-Induced Ovarian Damage"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Sara Di Persio (University hospital Münster, Germany)
"Single Cell RNA Sequencing Shed Light on the Cellular and Molecular Alterations Behind Two Distinct Types of Male Infertility"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Petra Lothert (Mayo Clinic Graduate School of Biomedical Sciences, United States)
"Activation of T Cells and Macrophages in Placenta Diagnosed with Villitis of Unknown Etiology Using Spatial Profiling"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Samuel Cripps (The University of Melbourne, Australia)
"Erectile Dysfunction on the Rise: Is Exposure to Endocrine-Disrupting Chemicals a Risk Factor?"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Mitch Harancher (Magee Women's Research Institute, University of Pittsburgh School of Medicine, United States)
"A Germline Gene Editing Approach to Address Iatrogenic Infertility and Disease Transmittance Using Sickle Cell Disease Models"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Pursuing a Career in the Reproductive Sciences
Discussion Leaders: Klementina Fon Tacer (Texas Tech University, United States) and Margeaux Marbrey (University of North Carolina at Chapel Hill, United States)
1:30 pm - 2:30 pm
Panel Discussion
Pursuing a Career in the Reproductive Sciences
Thomas Spencer (University of Missouri, United States)
Karina Rodriguez (National Institute of Environmental Health Sciences, NIH, United States)
Gregory Kopf (FHI 360, United States)
Daniel Johnston (National Institutes of Health, United States)
Sue Hammoud (University of Michigan, United States)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes