Safeguarding Fertility for the Present and Future

August 13 - 14, 2022

Chairs

and

Conference Description

Declining fertility in humans together with unknown causes of reproductive disease, effects of environmental stressors, and threats to survival of endangered species, all call for the continual advancements in reproductive biology research. This trainee-led seminar will provide a unique forum for graduate students, postdoctoral fellows, and veterinary and medical residents/fellows to discuss their recent discoveries, cutting-edge technologies, and vision for the future while presenting original work pertinent to mammalian reproduction. This multi-disciplinary seminar welcomes research spanning from gamete development to parturition, including novel studies describing reproductive disease, fertility preservation, environmental trans-generational effects, and innovative contraceptive strategies. Trainees will have opportunities to network, collaborate, and receive insight from successful senior investigators offering inspiration in the pursuit of scientific careers amid the rapidly changing scientific culture.

Young researchers attending this Gordon Research Seminar have the valuable opportunity, and are strongly encouraged, to also attend the associated Gordon Research Conference. Furthermore, financial support may be available for selected presenters and/or exceptional attendees from abroad. Please contact the organizers for more details.

Related Meeting

This GRS will be held in conjunction with the "Mammalian Reproduction" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:00 pm - 5:00 pm	Arrival and Check-in
3:30 pm - 3:45 pm	Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm	Keynote Session: Forefronts and Lessons in Reproduction Discussion Leader:
3:45 pm - 3:50 pm	Introduction by Discussion Leader
3:50 pm - 4:05 pm	"Here by Accident: Don’t be Afraid to Notice an Unanticipated Open Door"
4:05 pm - 4:10 pm	Discussion
4:10 pm - 4:25 pm	"Fertility Preservation for Kids"
4:25 pm - 4:30 pm	Discussion
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Developmental Mechanisms Driving Successful Reproduction Discussion Leaders: and
7:30 pm - 7:45 pm	"Regulation of Uterine NK Cell Subsets by Reproductive Hormones"
7:45 pm - 7:50 pm	Discussion
7:50 pm - 8:05 pm	"Modeling Human Trophoblasts: A Single-Cell Transcriptomic Characterization"
8:05 pm - 8:10 pm	Discussion
8:10 pm - 8:25 pm	"Comparative Analysis of Oocyte Development in Female Mice with Different Genetic Backgrounds"
8:25 pm - 8:30 pm	Discussion
8:30 pm - 8:45 pm	"Enhanced Naïve Pluripotent Stem Cells for Modelling Early Human Development"
8:45 pm - 8:50 pm	Discussion
8:50 pm - 9:05 pm	"Investigating Active Demethylation Pathways in Germline Epigenetic Reprogramming Using Novel Tet1 Mouse Mutants"
9:05 pm - 9:10 pm	Discussion
9:10 pm - 9:25 pm	"Is There a Second Sperm Factor in Mouse Sperm?"
9:25 pm - 9:30 pm	Discussion
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Impacts of Disease, Damage and Aging on Reproduction Discussion Leaders: and
9:00 am - 9:15 am	"FOXC1 Functions as a Proinflammatory Transcriptional Regulator in Endometriotic Lesions"
9:15 am - 9:20 am	Discussion
9:20 am - 9:35 am	"The Trials and Tribulations of Blocking PUMA for Fertility Preservation Against Chemotherapy-Induced Ovarian Damage"
9:35 am - 9:40 am	Discussion
9:40 am - 9:55 am	"Single Cell RNA Sequencing Shed Light on the Cellular and Molecular Alterations Behind Two Distinct Types of Male Infertility"
9:55 am - 10:00 am	Discussion
10:00 am - 10:15 am	"Activation of T Cells and Macrophages in Placenta Diagnosed with Villitis of Unknown Etiology Using Spatial Profiling"
10:15 am - 10:20 am	Discussion
10:20 am - 10:35 am	"Erectile Dysfunction on the Rise: Is Exposure to Endocrine-Disrupting Chemicals a Risk Factor?"
10:35 am - 10:40 am	Discussion
10:40 am - 10:55 am	"A Germline Gene Editing Approach to Address Iatrogenic Infertility and Disease Transmittance Using Sickle Cell Disease Models"
10:55 am - 11:00 am	Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Mentorship Component: Pursuing a Career in the Reproductive Sciences Discussion Leaders: and
1:30 pm - 2:30 pm	Panel Discussion Pursuing a Career in the Reproductive Sciences
2:30 pm - 3:00 pm	Evaluation Period Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm	Seminar Concludes

Contributors

Research reported in this publication was supported by the Eunice Kennedy Shriver National Institute Of Child Health & Human Development of the National Institutes of Health under Award Number R13HD102099. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Conference Links

Conference History Mammalian Reproduction

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