Monday Morning
SESSION 1:
GENES INVOLVED IN NORMAL MAMMARY GLAND DEVELOPMENT AND BREAST CANCER
Session Chair: Dr. Barbara Weber, University of Michigan Medical Center
"WNT-1 protein, a secreted factor and its role in cell proliferation and differentiation.", Dr. Jacqueline Papkoff,
SUGEN, Inc., California
"Role of the p53 suppressor gene in normal cells and deregulation in its activity in cancer cells.", Dr. Varda
Rotter, The Weizmann Institute, Israel
"BRCA1 - A breast cancer susceptibility gene.", Dr. Barbara Weber, University of Michigan Medical Center
Monday Evening
SESSION 2:
CELLULAR GROWTH MECHANISMS AND APOPTOSIS
Session Chair: Dr. Nancy Davidson, Johns Hopkins Oncology Center, Maryland
"Role of cyclins and cyclin-dependent kinases in the hormonal control of cell proliferation in normal and
neoplastic human mammary epithelium.", Dr. Robert Sutherland, Garvan Institute of Medical Research,
Australia
"Isolation and evaluation of cDNAs associated with apoptotic cell death of mammary epithelium",. Dr. Robert
Strange, AMC Cancer Research Center, Colorado
"Programmed cell death in human breast cancer cells.", Dr. Nancy Davidson, Johns Hopkins Oncology Center,
Maryland
Tuesday Morning
SESSION 3:
HORMONES AND GROWTH FACTORS
Session Chair: Dr. Gloria Heppner, Michigan Cancer Foundation
"Regulation of prolactin cell differentiation by a milk-borne peptide.", Dr. Stephen Frawley, University of South
Carolina
"The MCF-10AneoT xenograft model of preneoplastic proliferative breast disease." Dr. Gloria Heppner,
Michigan Cancer Foundation
"The biological significance of variant estrogen receptor expression.", Dr. Leigh Murphy, The University of
Manitoba, Canada
"Agonist effects of antagonist-occupied progesterone B-receptors: New models of hormone-resistant breast
cancer." Dr. Kathryn Horwitz, University of Colorado School of Medicine
Tuesday Evening
SESSION 4:
EPITHELIAL-STROMAL INTERACTIONS
Session Chair: Dr. Sandra Haslam, Michigan State University
"Epithelial-stromal cell interactions and ovarian hormones in growth factor regulated normal mammary gland
growth.", Dr. Sandra Haslam, Michigan State University
"Matrix-degrading metalloproteinases in mammary gland development.", Dr. Lynn Matrisian, Vanderbilt
University, Tennessee
"Epithelial-stromal interaction in human breast cancer.", Dr. Ole Petersen, University of Copenhagen, Denmark
Wednesday Morning
SESSION 5:
SIGNAL TRANSDUCTION PATHWAYS
Session Chair: Dr. Mina Bissell, Lawrence Berkeley Laboratory, California
"Looking at breast cancer from a different angle: Lessons from normal tissues.", Dr. Mina Bissell, Lawrence
Berkeley Laboratory, California
"Receptors of the tyrosine kinase family and the cytokine super-family cooperate to promote differentiation of
the mammary gland." Dr. Nancy Hynes, Friedrick Miescher Institut, Switzerland
"Significance of the co-expression of the erbB-2/4 receptor and gp30/heregulin in breast cancer progression.",
Dr. Ruth Lupu, Lombardi Cancer Research Center, Georgetown University, Washington, D.C.
Wednesday Afternoon
WORKSHOP:
DISCUSSION OF SELECTED POSTERS PRESENTED BY GRADUATE STUDENTS AND
POSTDOCTORAL FELLOWS
Session Chairs: Dr. Bonnie Asch, Roswell Park Cancer Institute, New York and Dr. Craig Baumrucher,
Pennsylvania State University
Wednesday Evening
SESSION 6:
LIFESTYLES AND BREAST CANCER
Session Chair: Dr. Henry Thompson, AMC Cancer Research Center, Colorado
"Mammary cancer prevention by minor dietary constituents.", Dr. Clement Ip, Roswell Park Cancer Institute,
New York
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