Session 1: Sun PM - June 15, 1997

Issues in Mammary Gland Biology.

1. Barbara Vonderhaar, NIH, Bethesda MD, USA - "Perspectives on Mammary Gland Biology into the next Millennium"
2. Polly Newcomb, Fred Hutchinson Cancer Research Center, Seattle, WA, USA - "Pregnancy, Lactation, and Breast Cancer Risk in Women."
3. Dan Medina, Baylor Univ., Houston, TX, USA - "Mammary Development and Neoplasia."

Welcoming Reception - 9:30 pm

Session 2: Mon AM - June 16, 1997

Genetic Basis for Breast Cancer.

1. Lewis Chodosh, Univ. Pennsylvania School of Medicine, Philadelphia PA, USA - "Tumor suppressor genes in normal and neoplastic mammary development."
2. Wen-Hwa Lee, Univ. Texas Health Science Center, San Antonio TX, USA - "Biological function of BRCA1."
3. Roy A. Jensen, Vanderbilt U., Nashville TN, USA - "Cell Biology of the BRCA1 gene product."
4. Bonnie Asch, Roswell Park Cancer Institute, Buffalo, NY - "Loss of Gelsolin in Human and Rodent Breast Cance."

Session 3: Mon PM - June 16, 1997

Estrogens in Mammary Development and Cancer.

1. Christina Teng, National Institute of Environmental Health Science, Research Triangle, NC, USA - "Molecular basis for species differences in estrogen and growth factor regulation of lactoferrin."
2. Steven Safe, Texas A&M University, College Station, TX, USA - "Estrogenic and Antiestrogenic activity for Xenoestrogens."
3. David Kleinberg, N Y Univ. Med Ctr, NY, NY USA - "Estrogen, IGF-1, and growth hormone interactions in mammary development."

Session 4: Tues AM - June 17, 1997

Prolactin in Mammary Regulation

1. Charles Brooks, Ohio St. Univ, Columbus OH, USA - "Growth hormone and prolactin: Identification of the lactogenic motif."
2. Paul Kelly , INSERM, Paris, FRANCE - "Prolactin receptor signal transduction and phenotypes in Prl-R knockout mice."
3. Bernd Groner ,University of Freiburg ,Freiburg, GERMANY - "STAT5/MGF: a central mediator of prolactin signaling in the mammary gland."
4. Steve Anderson, Univ. Colo. Health Sci Ctr, Denver CO, USA - "Prolactin signaling and autocrine regulation in mammary cancer cells."

Session 5: Tues PM - June 17, 1997

Transcription Factors & Cell Signaling in Mammary Regulation

1. Wolfgang Doppler, University of Innsbruck, Innsbruck, AUSTRIA - "C/EBP isoforms and glucocorticoid receptor regulation of mammary genes in pregnancy and lactation."
2. Charles Streuli , U. Manchester, Manchester UK - "STAT5 in mediation of mammary cell-ECM signaling."
3. Zena Werb, UCSF, San Francisco CA, USA - "Regulation of scheduled and unscheduled apoptosis in the mammary gland."
4. Xiuwen Liu, National Institutes of Health, Bethesda, MD - "Short Topic: JAK-STAT Signaling in Mammary Development and Physiology."

Session 6: Wed AM - June 18, 1997

Autocrine and Paracrine Factors in Mammary Development

1. Yael Friedmann, Hadassah University Hospital, Jerusalem ISRAEL - "Hox Genes in mammary development."
2. Walter Birchmeier, Max-Delbruck Ctr for Molelcular Med., Berlin GERMANY - "HGF and NDF in Mammary Development."
3. Kermit Carraway, Univ. Miami School of Medicine, Miami FL, USA - "Sialomucin/ErbB-2 ligand complex (ASGP-1/ASGP-2) in the mammary gland."
4. John Wysolmerski, Yale University School of Medicine, New Haven, Conn. USA - "PTHrP in mammary development."

Session 7: Wed PM - June 18, 1997

Secretion of Milk Components

1. Michelle Olivier-Bousquet, Biologie Cellulaire et Moleculaire, INRA, Jouy-en-Josas, FRANCE - "Transcytosis and the exocytotic pathway in the mammary cell."
2. Robert Burgoyne, Univ. Liverpool, Liverpool, UK - "Constitutive & Regulated Secretion Pathways in the Mammary Cell."
3. Tom Keenan, Virginia Polytechnic Institute and University, Blacksburg, VA, USA - "Role of adipocyte proteins in milk fat microdroplet synthesis & translocation."

Session 8: Thurs AM - June 19, 1997

Bioactive Components in Milk

1. David Newburg, Shriver Center for Mental Retardation, Waltham, MA, USA - "Human milk oligosaccharides and glycoconjugates inhibit human pathogens."
2. Jeremy Brock, Western Infirmary, Glasgow, Scotland UK - "Antimicrobial, immunoregulatory, & iron-scavenging activity of lactoferrin. "
3. Pedro Prieto, Ross Laboratories, Columbus OH, USA - "Human glycosyl transferase in transgenic mice makes 'human' oligosaccharides in milk."
4. Andrea Mastro, Penn. State University, University Park, PA, USA - "Is milk prolactin a modulator of immunological development in neonatal rats?"

Session 9: Thurs PM - June 19, 1997

Keynote Address

1. Jean-Claude Mercier, INRA, Jouy-en-Josas, FRANCE - "Milk proteins: from protein sequence to gene regulation."